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Yorva Sayoet
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POLA RESISTENSI KUMAN PENYEBAB DIARE TERHADAP ANTIBIOTIKA Yusri Dianne Jurnalis; Yorva Sayoet; Aslinar Aslinar
Majalah Kedokteran Andalas Vol 33, No 1: April 2009
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (430.867 KB) | DOI: 10.22338/mka.v33.i1.p%p.2009

Abstract

AbstrakResistensi kuman terhadap antibiotika sangat dipengaruhi oleh intensitas pemaparan antibiotika. Penggunaan antibiotika yang tidak rasional pada penyakit diare cenderung akan meningkatkan resistensi kuman yang semula sensitif. Perkembangan resistensi kuman terhadap antibiotika perlu dipantau agar dalam pengobatan penyakit diare dengan antibiotika dapat dilakukan pemilihan obat yang tepat.Untuk mengetahui pola resistensi kuman terhadap antibiotika pada pasien diare yang dirawat di bangsal IKA RS Dr. M. Djamil Padang dari Januari-Desember 2008.Data penelitian diperoleh dari catatan medik pasien diare yang dirawat di bangsal IKA dan dilakukan kultur dan sensitivitas dari sampel feses. Dilakukan uji resistensi terhadap kuman yang terdeteksi dengan antibiotika Ampisilin (Amp), Tetrasiklin (TE), Sulfametoxazole-Trimetoprim (STX), sebagai antibiotik ang paling banyak digunakan pada pasien diare.Dari hasil uji kultur dan sensitivitas pada 173 sampel feses didapatkan 3 jenis kuman yang terbanyak yaitu E.Coli sebanyak 92 (51.4%), Klebsiela sp 30 (16.8%), dan kuman Enterobacter sp 28 (15.6%). Resistensi kuman E.Coli terhadap antibotika AMP sebesar 53.3%, terhadap TE 67.4% dan terhadap STX 87%. Resistensi kuman Klebsiela sp terhadap antibiotika AMP sebesar 46%, terhadap TE 40% dan terhadap STX 73.3%. Dan resistensi kuman Enterobacter sp terhadap antibotika AMP sebesar 64.3%, terhadap TE 75% dan terhadap STX 82,1%.Kuman penyebab diare menunjukkan resistensi yang tinggi terhadap Sulfametoxazole-Trimetoprim (STX).Kata kunci. resistensi, antibiotika, diareAbstractMicroorganisme resistance against antibiotic is highly influenced by intensity of antibiotics exposure. Irrational use of antibiotics in diarrhea tends to increase resistance of previously sensitive microorganism. Monitoring in antibiotics development resistance is required to achieve appropriate diarrhea therapy.ARTIKEL PENELITIAN42To assess microorganism resistance pattern against antibiotics in diarrhea patients hospitalized at Dr. M. Djamil General Hospital pediatric ward from January – December 2008.Study data obtained from culture of feces of diarrhea patients hospitalized in pediatric ward. Resistance test were performed using antibiotics Ampicillin (Amp), tetracycline (TE), sulphamethoxazole-trimethoprim (SXT), as the 3 most common antibiotic used for diarrhea.There were 173 feces samples performed culture and sensitivity test. Three microorganism species found frequently were E. coli (92; 51.4%), Klebsiella sp. (30; 16.8%), Enterobacter sp. (28; 15.6%). E. coli resistance to AMP were 53.3%, TE 67.4%, and SXT 87%. Resistance of Klebsiella sp. to AMP 46.7%, TE 40%, and SXT 73.3%. Enterobacter sp. resistance were 64.3%, 75%, and 82.1%, respectively.Sulphamethoxazole-trimethoprim was the highest resistance antibiotics against microorganism in acute diarrhea patients.Keywords : resistance, antibiotics, diarrhea
HELICOBACTER PYLORI INFECTION IN CHILDREN Yusri Dianne Jurnalis; Yorva Sayoet; Sari Dewi
Majalah Kedokteran Andalas Vol 35, No 1 (2011): Published in April 2011
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (200.749 KB) | DOI: 10.22338/mka.v35.i1.p43-49.2011

Abstract

AbstrakFaktor risiko infeksi Helicobacter pylori adalah tinggal di negara berkembang, kondisi sosial ekonomi yang rendah, jumlah anggota keluarga yang banyak, etnik dan genetik. Tatalaksana dan diagnosis Helicobacter pylori belum memuaskan karena adanya resistensi antibiotik pada pasien Helicobacter pylori. Kami melaporkan seorang pasien perempuan usia 8 tahun 6 bulan yang terinfeksi Helicobacter pylori. Diagnosis ditegakkan berdasarkan anamnesis, pemeriksaan fisik, dan hasil laboratorium. Pasien diduga terinfeksi Helicobacter pylori karena mengalami nyeri perut berulang. Dari laboratorium didapatkan serologi IgG Helicobacter pylori positif. Pada hasil endoskopi biopsi ditemukan kuman Helicobacter pylori. Pasien mendapat therapi eradikasi lini pertama untuk infeksi Helicobacter pylori yaitu amoksisilin, klaritromisin dan omeprazol selama dua minggu. Setelah dua minggu pengobatan keluhan pasien tidak ada.Kata kunci: Helicobacter pylori, anak, nyeri perut berulangAbstractRisk factors for acquiring Helicobacter pylori infection include residency of developing country, poor socioeconomic conditions, crowded family, and possibly an ethnic or genetic as predispositions. The diagnosis and management Helicobacter pylori has not been satisfied yet, however, there is problem of increasing resistancy antibiotic due to Helicobacter pylori. Objective: We report a 8 year and 6 month old girl who suffered from Helicobacter pylori. The diagnosis was based on history, clinical finding, and laboratory work-up. Suspicion on the presence of Helicobacter pylori was started when the girl had recurrent abdominal pain. Serology IgG Helicobacter pylori was positive and we had done endoscopic examination and biopsy. Therapy this patient was first line eradication Helicobacter pylori which give amoxicillin, clarithromycin and omeprazole for two weeks. There are no sympthoms after two weeks therapyKey word: Helicobacter pylori, children, recurrent abdominal painLAPORAN KASUS
Co-Authors Aslinar Aslinar Sari Dewi Yusri Dianne Jurnalis