Erlinda Widyastuti, Erlinda
Department Of Health, Faculty Of Vocational Education, Universitas Airlangga, Surabaya, Indonesia

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Jumlah Leukosit, Trombosit, dan Kadar Kreatinin Pada Pasien Sepsis Covid-19 Di RSUD Genteng Banyuwangi Pada Periode 2020-2021 Rezita Nurul Magfiroh; Nur Septia Handayani; Erlinda Widyastuti; Belgis Belgis
Jurnal Medika Nusantara Vol. 2 No. 2 (2024): Mei : Jurnal Medika Nusantara
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/medika.v2i2.991

Abstract

One of the medical conditions that leads to the highest death rate worldwide is sepsis. In the presence of several variables and concomitant conditions, the mortality rate from sepsis keeps rising in proportion to the severity of the condition. It is quite concerning when sepsis patients have proven COVID-19. Some patient subgroups and inflammatory mediators may have increased cytokine release as a result of the SARS-CoV-2 virus. A number of laboratory tests can be used to diagnose COVID-19 and sepsis, one of which is counting leukocytes, platelets, and creatinine levels as indicators of organ failure. The purpose of this study is to characterize the platelet, leukocyte, and creatinine levels in individuals who have been diagnosed with COVID-19 sepsis. This study's methodology employed a descriptive observational technique using 36 patient samples from Genteng Banyuwangi General Hospital, selected based on laboratory examination results (leukocyte count, platelets, and creatinine levels), as well as characteristics related to gender, age, comorbidities, and hospital discharge status. The findings revealed that female patients aged 20 (55.6%) made up the bulk of patients with confirmed COVID-19 sepsis, whereas the largest age group consisted of 9 (56.25%) individuals who were over 60. Twenty-two (61.1%) sepsis patients with proven COVID-19 had a high leukocyte count, and of those with confirmed COVID-19 and sepsis, the majority had normal platelets depending on the platelet count. Nine (56.25%) male patients with confirmed COVID-19 sepsis had elevated creatinine levels, whereas 10 (50%) female patients had normal findings. Patients with sepsis who had verified COVID-19 were generally deceased upon hospital release, with no comorbidities in 14 patients (or 50% of the total), and diabetes mellitus in 13 patients (or 46.4%).
LAMELLAR BODY COUNT WITH CELL DYN EMERALD AND CELL DYN RUBY METHODS ON PRETERM BIRTH Widyastuti, Erlinda; Imandiri, Ario
Journal of Vocational Health Studies Vol. 1 No. 1 (2017): July 2017 | JOURNAL OF VOCATIONAL HEALTH STUDIES
Publisher : Faculty of Vocational Studies, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jvhs.V1.I1.2017.7-10

Abstract

Background: Lamellar bodies are produced by pneumocyte type II cells in the lung alveoli. Lamellar bodies are present in amniotic fluid in increasing quantities as gestation advances, 1 – 5 µm in size, similar in size to small platelets and can be counted on most electronic cell counters in hematology analyzer. Lamellar body count is useful for prediction of fetal lung maturity and neonatal respiratory distress syndrome. The current gold standard for determination of fetal lung maturity is the evaluation of phospholipids in amniotic fluid samples by thin-layer chromatography, but it is time-consuming and not continuously available at most institutions. In this study we compare Cell Dyn Emerald and Cell Dyn Ruby method, which is expected to be a review for lamellar body count method. Purpose:  The aim of this study was to analyze lamellar body count with Cell Dyn Emerald and Cell Dyn Ruby method on preterm birth. Method: This was a cross sectional study. Thirty three samples study were inpatient's amniotic fluid with premature rupture of membranes in Obstetry and Gynecology ward emergency room Dr. Soetomo Hospital Surabaya. Lamellar body count was counted with Cell Dyn emerald and Cell Dyn Ruby method. The statistical differences were assessed using the ANOVA test . Result: The results showed significant differences (t=49,04), lamellar body count with Cell Dyn Ruby method was much lower than Cell  Dyn Emerald method. The lowest result with Cell Dyn Ruby method was 3.38 x 103/µL and 17 x 103/ µL with Cell Dyn Emerald method. The highest results with Cell Dyn Ruby method was 98,2 x 103/ µL and 221 x 103/ µL with Cell Dyn Emerald method. Conclusion: Lamellar body count with impedance method (Cell Dyn Emerald) is significantly higher than optic method (Cell Dyn Ruby).
STATE ANXIETY INVENTORY SCORE AMONG STUDENTS WITH FINAL ASSIGNMENT Imandiri, Ario; Widyastuti, Erlinda; Jonosewojo, Arijanto
Journal of Vocational Health Studies Vol. 1 No. 1 (2017): July 2017 | JOURNAL OF VOCATIONAL HEALTH STUDIES
Publisher : Faculty of Vocational Studies, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jvhs.V1.I1.2017.11-14

Abstract

Background: Students final assignment is a scientific work requires precision, time consuming, energy as well as concentrations. Students may experience stress within the process of completing the final assignment, which can lead to variety of disorder; physical, emotional, intellectual and interpersonal. Purpose: The aim of this study was to determine the state anxiety inventory scores among final students with scientific project. Those score were then being used as preliminary data to decide the next step of the study which are giving acupuncture therapies to those students with high score of anxiety.  Method: This was a descriptive study with one shot/cross sectional study, using questionnaires distributed to respondents for data completion. Respondents were 100 students from Faculty of Vocational Education Universitas Airlangga who were taking the final assignment subject. Result: The results of State Anxiety Inventory Score were obtained as average score of 53.03 with standard deviation of 10.4. Conclusion: The mean values showed a reasonably anxious outcome.
CORRELATION BETWEEN SGOT AND SGPT LEVELS WITH POSITIVE HBsAg LEVELS Rosyidah, Nisa'ur; Widyastuti, Erlinda; Rahman, Annisa Auliya; Handayani, Nur Septia; Belgis
Journal of Vocational Health Studies Vol. 8 No. 1 (2024): July 2024 | JOURNAL OF VOCATIONAL HEALTH STUDIES
Publisher : Faculty of Vocational Studies, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jvhs.V8.I1.2024.1-6

Abstract

Background: Serum Glutamic Oxaloacetate Transaminase (SGOT) and Serum Glutamic Pyruvic Transaminase (SGPT) are transaminase enzymes used to determine liver damage. The increase in both enzymes can indicate the level of liver cell damage. Hepatitis B surface antigen (HBsAg) is an antigen that can indicate an acute infection or a chronic carrier. Purpose: This study aims to determine the correlation between SGOT and SGPT levels with positive HBsAg levels. Method: It is a cross-sectional study using medical records from patients with positive HBsAg who performed SGOT and SGPT examinations at the Haji Public Hospital, East Java Province, in 2021. The correlation analysis used in this study is Kendall's tau correlation because the data contains outliers and is not normally distributed. Result: Based on the results, it is known that there is no significant correlation between SGOT and SGPT levels with positive HBsAg levels. The correlation coefficient for each is 0.110 and 0.144. Conclusion: It can happen because HBsAg levels vary between the disease's different phases, the patient's characteristics, and the levels of SGOT and SGPT.
THE TOTAL LEUKOCYTE COUNT OF ELDERLY PATIENTS CONFIRMED COVID-19 WITH/WITHOUT A VENTILATOR IN A SURABAYA GENERAL HOSPITAL IN 2021 Fitriani, Safira Indah; Handayani, Nur Septia; Widyastuti, Erlinda; Kurniati, Anita
Journal of Vocational Health Studies Vol. 7 No. 1 (2023): July 2023 | JOURNAL OF VOCATIONAL HEALTH STUDIES
Publisher : Faculty of Vocational Studies, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jvhs.V7.I1.2023.55-62

Abstract

Background: Coronavirus is a virus that attacks the immune system, especially the human respiratory system. The elderly are at high risk of being infected with Coronavirus Disease-19 (COVID-19), and as they get older, they are at risk of experiencing severe symptoms when infected with COVID-19. Leukocytes play a role in the immune system against foreign objects. The leukocyte count will decrease in the elderly. On the other hand, the increase of leukocytes plays a role as a clinical sign that is useful to be a predictor of body immunity when infected with COVID-19. Purpose: To determine the total leukocyte count in elderly patients that were confirmed COVID-19 and hospitalized with and without a ventilator. Method: This study was a cross-sectional design study involving 93 elderly patients in General Hospital Surabaya. Result: The results showed no difference in the total leukocyte count in elderly hospitalized patients with and without a ventilator (p-value = 0.756). Age above 70 years old increases the risk of patients requiring a ventilator up to 1.7 times compared to patients under 70 years old. The highest leukocyte count was 20.880/mm3, and the lowest was 3.760/mm3. The ratio of leukocyte count in elderly patients with a ventilator group is 1 : 3 for low and high leukocyte counts, respectively. Conclusion: Leukocyte count is an important parameter as the predictor of the progression of the disease and helps in the decision regarding treatment strategy to prevent the cytokine storm.