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All Journal Berkala Ilmiah Kedokteran Duta Wacana MEDICINUS
Christiane Marlene Sooai
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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DEPRESI PASCA SKIZOFRENIA Christiane Marlene Sooai
Berkala Ilmiah Kedokteran Duta Wacana Vol 1, No 3 (2016): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (169.025 KB) | DOI: 10.21460/bikdw.v1i3.19

Abstract

Gangguan jiwa merupakan masalah kesehatan yang menglobal, berdasarkan data WHO pada tahun 2013, terdapat 450 juta orang yang mengalami gangguan jiwa atau setidaknya 1 dari 4 orang di dunia mengalami masalah mental dan masalah kesehatan jiwa. Menurut sumber yang sama, Skizofrenia merupakan salah satu bentuk gangguan jiwa berat yang dialami 21 juta orang diseluruh dunia. Psikosis, termasuk skizofrenia dengan karakteristik gangguan pada pola berpikir, persepsi, emosi, bahasa, serta kesadaran diri dan tingkah laku. Gejala psikotik yang biasa ditemukan adalah halusinasi pendengaran, penglihatan, dan delusi.
Association Between Neutrophil-to-Lymphocyte Ratio (NLR) and Dengue Severity in Patients Treated at Bethesda Hospital, Yogyakarta Jingan, Forensius; Christiane Marlene Sooai; Loury Priskila; Pradita Sri Mitasari; Wiwiek Probowati; Priskila, Loury
MEDICINUS Vol. 38 No. 10 (2025): MEDICINUS
Publisher : PT Dexa Medica

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56951/11a64f98

Abstract

Background: Dengue fever, a mosquito borne viral infection, remains a major public health concern in Indonesia, with the challenges in early identification of severe cases. The neutrophil-to-lymphocyte ratio (NLR) has emerged as a potentialbiomarker for assessing the disease severity.Objective: This study aimed to investigate the association between NLR and dengue severity in patients treated at Bethesda Hospital, Yogyakarta.Methods: A cross-sectional, quantitative study was conducted using medical record data from dengue patients admitted between 2022 to 2024. The NLR values were calculated from complete blood count results and disease severity was classified according to WHO guidelines. Statistical analysis was performed using the chi-square test and Fisher’s exact test.Results: Among the 68 patient samples, a significant association was found between NLR and dengue severity (p<0.001). Patients with lower NLR values were more likely to develop dengue hemorrhagic fever (DHF) compared to those with higher NLR values.Conclusion: The NLR plays a role in determining the severity of dengue infection and may serve as a predictive biomarker. This examination can be a practical tool in the clinical management of dengue fever patients, particularly for early detectionand optimizing therapeutic decision-making.
Co-Authors Jingan, Forensius Loury Priskila Pradita Sri Mitasari Priskila, Loury Wiwiek Probowati