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All Journal Berkala Ilmiah Kedokteran Duta Wacana Callosum Neurology Journal : Jurnal Berkala Neurologi Bali Journal Of Widya Medika Junior Aesculapius Medical Journal Journal of Pain, Vertigo and Headache Jurnal Atma Inovasia Proceeding ISETH (International Summit on Science, Technology, and Humanity) Cermin Dunia Kedokteran Journal of Neurointervention and Stroke (JNeViS)
Lothar Matheus Manson Vanende Silalahi
Medical Faculty, Universitas Kristen Duta Wacana
Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Education Engineering Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health Social Sciences Other

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HEMORRHAGIC STROKE PROFILE ON SALATIGA REGIONAL PUBLIC HOSPITAL PATIENTS Garudadwiputra, Ian A; Silalahi, Lothar M M V; Manus, Widya C
JOURNAL OF WIDYA MEDIKA JUNIOR Vol 4, No 1 (2022): January
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwmj.v4i1.3584

Abstract

ABSTRACTIntroduction: There is an increasing number of new hemorrhagic stroke cases from 2017 to 2018 on The Province of Central Java and Salatiga. A study of demographics, laboratory examination, radiology, outcome, risk factor, and clinical presentation on hemorrhagic stroke patients are rarely done at Salatiga Regional Public Hospital. Objectives: This study aims to describe the hemorrhagic stroke profile on Salatiga Regional Public Hospital patients. Materials and Methods: Hemorrhagic stroke inpatient of Salatiga Regional Public Hospital in the period between October 2018 and October 2019 is studied. Demographic, laboratory examination, radiology, outcome, risk factor, and clinical presentation data are reported. Results: From a total of 192 data gathered, 120 meet the inclusion and exclusion criteria. 47,5% male and 52,5% female with highest age range (55-64) 33%. The majority of patients came from outside of Salatiga city 71,7%. Patients with blood pressure classification stage 1 11,7%; stage 2 80%. Laboratory examination data shows 52,5% high leucocyte count; normal thrombocyte count; normal lymphocyte count; normal monocyte count; 72,5% high neutrophil count; 71,7% high Neutrophil-Lymphocyte Ratio; 89,2% high ureum level; normal creatine serum; 80% not at risk based on eGFR. Types of hemorrhages are ICH, IVH, and SAH with percentages 68,7%; 25,3%; 6% respectively. Basal Ganglia (48,1%) are the most common location for ICH and lateral ventricle (61,9%) are the highest for IVH. Clinical presentation for GCS (14-15) are the highest 58%. Patients with mortality are dominant in males with mean age 59,61 (year); followed by high counts of leucocyte, neutrophil, NLR, and ureum. Conclusion: Hemorrhagic stroke patients at Salatiga Regional Public Hospital are mainly female with the age range of 55-64 are the highest, came from outside of Salatiga city. The most frequent risk factor is hypertension. Most patients have GCS of 14-15 and stage 2 blood pressure classification. Most of the patient have leucocytosis, neutrophillia, high NLR and ureum level. ICH is the highest stroke subtype with the most frequent location of basal ganglia. More patients with good outcomes compared with a bad outcome.
TUMOR OTAK METASTASIS DARI KANKER PAYUDARA Lothar Silalahi; Eli Rahmi; Sri Sutarni
Berkala Ilmiah Kedokteran Duta Wacana Vol 3, No 1 (2018): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (4157.702 KB) | DOI: 10.21460/bikdw.v3i1.116

Abstract

Tumor intrakranial metastasis lebih banyak insidensinya dibandingkan tumor intrakranial primer. Kanker payudara merupakan penyebab ke dua terbanyak tumor otak metastasis.Melaporkan sebuah kasus tumor otak metastasis dari kanker payudara. Laporan kasus. Perempuan usia 36 tahun, dengan riwayat terdiagnosis kanker payudara, menjalani terapi pembedahan dan kemoterapi 1 tahun sebelumnya, datang dengan keluhan nyeri kepala kronik progresif.Tumor otak metastasi dari kanker payudara dapat muncul pada rentang usia produktif sampai usia tua, dengan gejala klinis paling banyak adalah nyeri kepala. Jenis histologis, jumlah lesi metastasis, performa klinis serta usia saat terdiagnosis kanker payudara dapat menjadi faktor prognosis tumor otak metastasis dari kanker payudara.
VIPERIDAE SNAKE BITE: KASUS SERIAL Alfi Rizky Medikanto; Lothar Matthaeus Manson Vanende Silalahi; Sri Sutarni
Berkala Ilmiah Kedokteran Duta Wacana Vol 2, No 2 (2017): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (520.361 KB) | DOI: 10.21460/bikdw.v2i2.61

Abstract

Latar Belakang: Gigitan ular merupakan salah satu kegawatdaruratan medis dan penyakit akibat okupasi yang sering diabaikan oleh tenaga medis, paramedis maupun pemangku kebijakan kesehatan sehingga sangat terbatas untuk dipelajari karena sistem pelaporan yang lemah. Ular golongan Viperidae sering ditemukan di wilayah Asia Tenggara memiliki bisa dengan kandungan hematotoksin dengan mekanisme aktivasi faktor koagulasi, trombositopenia, hiperfibrinolisis, dan koagulasi intravaskular luas. Laporan Kasus: Dilaporkan dua kasus gigitan ular golongan Viperidae. Kasus pertama seorang pria, 73 tahun datang dengan gigitan ular pada pergelangan kaki kiri. Pasien mengalami penurunan kesadaran, anemia, koagulopati, insufisiensi renal, dan perdarahan saluran kemih. Pemeriksaan funduskopi dan CT scan kepala tidak didapatkan perdarahan. Kasus kedua adalah seorang pria, 58 tahun datang dengan gigitan ular pada pergelangan kaki kanan. Pasien mengalami penurunan kesadaran, anemia, gangguan fungsi hati, koagulopati, perdarahan saluran kemih, dan hiponatremia. Kesimpulan: Manifestasi klinis gigitan ular Viperidae dapat berefek pada sistem koagulasi dan jika tidak ditangani dengan tepat dapat menyebabkan gangguan sistem saraf pusat, kardiovaskular dan urogenital
DIFFUSE-WEIGHTED MAGNETIC RESONANCE IMAGING (DW-MRI) FOR CRYPTOGENIC STROKE DIAGNOSIS IN YOUNG ADULT FEMALE: A CASE REPORT Lothar Matheus Manson Vanende Silalahi
Berkala Ilmiah Kedokteran Duta Wacana Vol 5, No 1 (2020): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v5i1.165

Abstract

Background: Ischaemic stroke is caused by various aetiology. Cryptogenic stroke diagnosis is established when no aetiologies are discovered although clinical manifestations are consistent with acute stroke. Diffusion-weighted magnetic resonance imaging (DW-MRI) is one neuroimaging modalities which could be useful in exploring aetiology instead of excluding intracranial haemorrhage. There are many conflicting pieces of evidence of the benefit using DW-MRI to confirm the presence or the absence of brain lesions. Objective: To report a clinical case of ischemic stroke with negative evaluation on advanced neuroimaging studies (DW-MRI). Case Description: A female, 35 years old, presented to the emergency unit with a 6 hours history of prickling sensation before admission. There were no risk factors of stroke, and no other neurological symptoms. The neurologic examination reveals left hemihypesthesia, with normal results on laboratory examination for stroke risk factors and negative ischemic lesion on brain DW-MRI. Explorative examination on cardiac aetiologies was negative. Patient was given a standard regimen for acute stroke management despite the negative results and established as a cryptogenic stroke case. Conclusion: Diagnosis of ischemic stroke should rely mainly on clinical findings, with consideration of cryptogenic stroke when there is no aetiology found after thorough examination. Nevertheless, comprehensive examination on cardiac function and coagulation tests should be performed whenever possible to determine the cause of ischaemic stroke.
PEDIATRIC HEALTHCARE SERVICE FOR AS A PART OF INDONESIAN FUTURE Lothar Matheus Manson Vanende Silalahi
Berkala Ilmiah Kedokteran Duta Wacana Vol. 6 No. 1 (2021): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v6i1.302

Abstract

Continuing and accelerating child health are issues stated in Sustainable Development Goals (SDG) by United Nation (UN). Targets in improving child health in SDG are by decreasing neonatal and pediatric mortality. Reducing risk and prevention of neonatal mortality may be achieved by monitoring intrauterine fetal development. High burden of pediatric mortality may be seen in pediatric genetic, neoplasm and infectious disease. In this COVID-19 pandemic era, SARS-COV2 infection in children add more challenge in improving child health. In this issue, we proudly present articles on pediatric genetic, neoplasm and infectious disease especially in clinical manifestation, diagnostic and therapeutic challenge.
PERAN PEMERIKSAAN ELEKTROFISIOLOGI DALAM DIAGNOSIS SINDROM MILLER-FISHER Ahmad Asmedi; Sekar Satiti; Lothar Matheus Manson Vanende Silalahi
Callosum Neurology Vol 3 No 2 (2020): Callosum Neurology Journal
Publisher : The Indonesia Neurological Association Branch of Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (182.556 KB) | DOI: 10.29342/cnj.v3i2.104

Abstract

Sindrom Miller-Fisher merupakan salah satu varian Sindrom Guillain-Barre yang memiliki gambaran klinis unik dengan trias klasik optalmoplegia, ataksia dan arefleksia. Pemeriksaan penunjang pada Sindrom Miller-Fisher berperan penting karena beberapa kondisi penyakit juga dapat bermanifestasi seperti trias klasik Sindrom Miller-Fisher. Penunjang berupa analisis cairan serebrospinal, pencitraan otak, biomarker antibodi GQ1b telah banyak digunakan untuk menegakkan diagnosis Sindrom Miller-Fisher namun memiliki keterbatasan. Pemeriksaan elektrofisiologi kemudian banyak diteliti karena selain menunjang diagnosis dapat menjelaskan proses penyakit Sindrom Miller-Fisher. Penulisan ini bertujuan untuk membahas peran pemeriksaan elektrofisiologi dalam diagnosis Sindrom Miller-Fisher. Hasil studi menunjukkan bahwa abnormalitas amplitude Sensory Nerve Action Potential (SNAP) dan H-reflex secara konsisten terjadi pada Sindrom Miller-Fisher. Abnormalitas amplitudo SNAP akan membaik dengan cepat dan reversibel sehingga diperlukan juga pemeriksaan elektrofisiologi serial untuk dapat menunjang diagnosis Sindrom Miller-Fisher. Temuan tersebut dapat diperkuat dengan hasil pemeriksaan konduksi saraf motorik, konduksi saraf sensorik dan F-wave yang normal. Kata Kunci: Sindrom Miller-Fisher, Elektrofisiologi, Diagnosis
CLINICAL MANIFESTATIONS OF ISCHEMIC STROKE IN VERTEBROBASILARY ARTERY INSUFICIENCY USING NON-CONTRAST CT-SCAN Hanson, Jevenzley Maxvell; S, Sudharmaji; Lestari, Dewi; Silalahi, Lothar Matheus Manson Vanende
Journal of Pain, Headache and Vertigo Vol. 5 No. 2 (2024): September
Publisher : PERDOSNI (Perhimpunan Dokter Spesialis Neurologi Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jphv.2024.005.02.03

Abstract

Stroke was the highest cause of death in the world in 2015. Stroke was the highest cause of death in Indonesia in 2019. DIY Province was ranked 2nd in most stroke cases in Indonesia in 2018. The severity level of the clinical manifestation of ischemic stroke due to vertebrobasilar artery insufficiency is the worst compared to other areas. This research uses a quantitative descriptive method with a retrospective design. The subjects of this research were ischemic stroke patients at Bethesda Hospital Yogyakarta for the period January 2023. This research used a total sampling technique. Vertebrobasilar artery insufficiency data was obtained from non-contrast CT-scan readings in an umbrella study by dr. Sudharmaji, Sp.Rad. Data on clinical manifestations were obtained from medical records. Data were analyzed using univariate tests with Microsoft Excel. There were 30 research samples with distribution of infarct locations in the cerebellum (6), medulla oblongata (1), occipital lobe (8), pons (15), thalamus (3), and patients whose focal parenchymal lesions were not clearly visualized (3). The distribution of clinical manifestations found was right ipsilateral hemiparesis (11), dysarthria (11), vertigo (11), left ipsilateral hemiparesis (8), alternans hemiparesis (1), dysphagia (2), diplegia (1), drop attack (1), polyuria (1), and others (1). The distribution of the most clinical manifestations is ipsilateral right hemiparesis, dysarthria, and vertigo.
JOGJA SAPA LANSIA Silalahi, Lothar Matheus Manson Vanende; The Maria Meiwati Widagdo; Mitra Andini Sigilipoe
Jurnal Atma Inovasia Vol. 5 No. 1 (2025)
Publisher : Lembaga Penelitian dan Pengabdian pada Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24002/jai.v5i1.10224

Abstract

Pendahuluan. Lanjut usia (lansia) dengan disabilitas mempunyai keluhan kesehatan paling tinggi. Meskipun keluhan kesehatannya paling tinggi, lansia dengan disabilitas merupakan populasi yang memiliki persentase paling tinggi yang tidak melakukan pengobatan. Minimnya pengobatan kesehatan ini juga menjadi risiko munculnya masalah kesehatan lain. Badan Perencanaan Pembangunan Daerah (Bappeda) Kota Yogyakarta berkolaborasi dengan Dinas Sosial Tenaga Kerja dan Transmigrasi (Dinsosnakertrans) Kota Yogyakarta melakukan kegiatan bertajuk “Jogja Sapa Lansia” berfokus pada lansia dengan disabilitas. Tujuan. Sebagai perwujudan Kota Yogyakarta ramah lansia. Metode. Program service learning bersama mahasiswa. Kegiatan yang dilakukan adalah dalam bentuk kunjungan ke lansia tirah baring. Dalam kunjungan mahasiswa melakukan observasi langsung dan eksplorasi masalah mengenai pemenuhan kebutuhan lansia. Asesmen menggunakan kuesioner short CANE (Camberwell Assessment Of Need For The Elderly). Hasil. Dilakukan kunjungan kepada sembilan lansia yang tirah baring dan didapatkan kebutuhan dominan yang belum terpenuhi adalah kebutuhan pendengaran/penglihatan, mobilitas dan dukungan sosial. Dari sisi caregiver kebutuhan lansia yang belum terpenuhi adalah kebutuhan informasi kondisi kesehatan. Mahasiswa kemudian melakukan edukasi sesuai dengan kondisi lansia. Kesimpulan. Lansia dengan tirah baring perlu dukungan lebih pada kondisi penglihatan/pendengaran, mobilitas, sosial dan informasi kondisinya.
Efektivitas Citicoline sebagai Terapi Gangguan Kognitif pada Stroke Iskemik Akut Lothar Matheus Manson Vanende Silalahi; Pradita Sri Mitasari
Cermin Dunia Kedokteran Vol 51 No 2 (2024): Dermatologi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v51i2.971

Abstract

Background: Cognitive impairment in acute ischemic stroke is associated with disability, poor functional outcome, and mortality, hence requires effective management. Citicoline is one of pharmacotherapy for central nervous system disorders. This study aims to evaluate current evidence of the effectiveness of citicoline for cognitive impairment in acute ischemic stroke. Methods: Systematic review and meta-analysis on randomized controlled trials searched in PubMed, Cochrane, and Google Scholar databases. Screening was done on 518 articles according to inclusion and exclusion criteria, 3 articles were qualified for review. Results: Cano-Cuenca, et al, (2015) found that citicoline was associated with a mini-mental state examination (MMSE) score of >25 at 12 weeks. Pinzon & Asanyi (2018) found that the use of citicoline can prevent cognitive impairment at 6 and 12 months, especially in attention and temporal orientation. Bonvicini, et al, (2022) found that citicoline is associated with good cognitive outcomes as measured with global cognitive impairment. Conclusion: Citicoline is effective as a therapy for cognitive impairment in acute ischemic stroke.
High Blood Osmolality is Associated with Poor Neurological Status in Acute Ischemic Stroke Patient on Admission Silalahi, Lothar Matheus Manson Vanende; Sutarni, Sri; Gofir, Abdul
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5519

Abstract

Purpose: The purpose of this study is to evaluate the association between high blood osmolality and neurological status in acute ischemic stroke. Methodology: This is a cross-sectional study. Subjects of this study are acute ischemic stroke patients admitted at Dr. Sardjito Hospital. Subjects who met the inclusion and exclusion criteria were analysed mainly the blood osmolality and NIHSS score at the time of admission. Results: The study involved 58 participants, with 29 (50%) exhibiting blood osmolality exceeding 300 mOsm/kg. A bivariate analysis revealed several factors significantly linked to poor neurological condition upon admission. These included elevated blood osmolality (OR=5,296, p=0,014, 95% CI, 1,29-21,7), presence of infection (OR=11,67, p=0,007, 95% CI, 1,95-6,99), increased white blood cell count (OR=4,750, p=0,028, 95% CI, 1,21-18,5), and an ASPECT Score below 7 (OR=14, p<0,001, 95%CI, 3,34-59). Multivariate analysis revealed that high blood osmolality (p=0,031) significantly associated with poor neurological status at the time of hospital admission. Applications: This study highlighted the importance of evaluating blood osmolality in acute ischemic stroke patients as it is associated with neurological deficit.
Co-Authors ., Subandi Abdul Gofir Ahmad Asmedi Alfi Rizky Medikanto Angelina Vivi Maharani Dewi Lestari Eli Rahmi Garudadwiputra, Ian A Hanson, Jevenzley Maxvell Loury Priskila Manus, Widya Christine Mitra Andini Sigilipoe Pradita Sri Mitasari Pradita Sri Mitasari S, Sudharmaji Sekar Satiti Sri Sutarni Sri Sutarni The Maria Meiwati Widagdo