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All Journal Berkala Ilmiah Kedokteran Duta Wacana Callosum Neurology Journal : Jurnal Berkala Neurologi Bali Journal Of Widya Medika Junior
Lothar Matheus Manson Vanende Silalahi
Medical Faculty, Universitas Kristen Duta Wacana
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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HEMORRHAGIC STROKE PROFILE ON SALATIGA REGIONAL PUBLIC HOSPITAL PATIENTS Garudadwiputra, Ian A; Silalahi, Lothar M M V; Manus, Widya C
JOURNAL OF WIDYA MEDIKA JUNIOR Vol 4, No 1 (2022): January
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwmj.v4i1.3584

Abstract

ABSTRACTIntroduction: There is an increasing number of new hemorrhagic stroke cases from 2017 to 2018 on The Province of Central Java and Salatiga. A study of demographics, laboratory examination, radiology, outcome, risk factor, and clinical presentation on hemorrhagic stroke patients are rarely done at Salatiga Regional Public Hospital. Objectives: This study aims to describe the hemorrhagic stroke profile on Salatiga Regional Public Hospital patients. Materials and Methods: Hemorrhagic stroke inpatient of Salatiga Regional Public Hospital in the period between October 2018 and October 2019 is studied. Demographic, laboratory examination, radiology, outcome, risk factor, and clinical presentation data are reported. Results: From a total of 192 data gathered, 120 meet the inclusion and exclusion criteria. 47,5% male and 52,5% female with highest age range (55-64) 33%. The majority of patients came from outside of Salatiga city 71,7%. Patients with blood pressure classification stage 1 11,7%; stage 2 80%. Laboratory examination data shows 52,5% high leucocyte count; normal thrombocyte count; normal lymphocyte count; normal monocyte count; 72,5% high neutrophil count; 71,7% high Neutrophil-Lymphocyte Ratio; 89,2% high ureum level; normal creatine serum; 80% not at risk based on eGFR. Types of hemorrhages are ICH, IVH, and SAH with percentages 68,7%; 25,3%; 6% respectively. Basal Ganglia (48,1%) are the most common location for ICH and lateral ventricle (61,9%) are the highest for IVH. Clinical presentation for GCS (14-15) are the highest 58%. Patients with mortality are dominant in males with mean age 59,61 (year); followed by high counts of leucocyte, neutrophil, NLR, and ureum. Conclusion: Hemorrhagic stroke patients at Salatiga Regional Public Hospital are mainly female with the age range of 55-64 are the highest, came from outside of Salatiga city. The most frequent risk factor is hypertension. Most patients have GCS of 14-15 and stage 2 blood pressure classification. Most of the patient have leucocytosis, neutrophillia, high NLR and ureum level. ICH is the highest stroke subtype with the most frequent location of basal ganglia. More patients with good outcomes compared with a bad outcome.
TUMOR OTAK METASTASIS DARI KANKER PAYUDARA Lothar Silalahi; Eli Rahmi; Sri Sutarni
Berkala Ilmiah Kedokteran Duta Wacana Vol 3, No 1 (2018): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (4157.702 KB) | DOI: 10.21460/bikdw.v3i1.116

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Tumor intrakranial metastasis lebih banyak insidensinya dibandingkan tumor intrakranial primer. Kanker payudara merupakan penyebab ke dua terbanyak tumor otak metastasis.Melaporkan sebuah kasus tumor otak metastasis dari kanker payudara. Laporan kasus. Perempuan usia 36 tahun, dengan riwayat terdiagnosis kanker payudara, menjalani terapi pembedahan dan kemoterapi 1 tahun sebelumnya, datang dengan keluhan nyeri kepala kronik progresif.Tumor otak metastasi dari kanker payudara dapat muncul pada rentang usia produktif sampai usia tua, dengan gejala klinis paling banyak adalah nyeri kepala. Jenis histologis, jumlah lesi metastasis, performa klinis serta usia saat terdiagnosis kanker payudara dapat menjadi faktor prognosis tumor otak metastasis dari kanker payudara.
VIPERIDAE SNAKE BITE: KASUS SERIAL Alfi Rizky Medikanto; Lothar Matthaeus Manson Vanende Silalahi; Sri Sutarni
Berkala Ilmiah Kedokteran Duta Wacana Vol 2, No 2 (2017): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (520.361 KB) | DOI: 10.21460/bikdw.v2i2.61

Abstract

Latar Belakang: Gigitan ular merupakan salah satu kegawatdaruratan medis dan penyakit akibat okupasi yang sering diabaikan oleh tenaga medis, paramedis maupun pemangku kebijakan kesehatan sehingga sangat terbatas untuk dipelajari karena sistem pelaporan yang lemah. Ular golongan Viperidae sering ditemukan di wilayah Asia Tenggara memiliki bisa dengan kandungan hematotoksin dengan mekanisme aktivasi faktor koagulasi, trombositopenia, hiperfibrinolisis, dan koagulasi intravaskular luas. Laporan Kasus: Dilaporkan dua kasus gigitan ular golongan Viperidae. Kasus pertama seorang pria, 73 tahun datang dengan gigitan ular pada pergelangan kaki kiri. Pasien mengalami penurunan kesadaran, anemia, koagulopati, insufisiensi renal, dan perdarahan saluran kemih. Pemeriksaan funduskopi dan CT scan kepala tidak didapatkan perdarahan. Kasus kedua adalah seorang pria, 58 tahun datang dengan gigitan ular pada pergelangan kaki kanan. Pasien mengalami penurunan kesadaran, anemia, gangguan fungsi hati, koagulopati, perdarahan saluran kemih, dan hiponatremia. Kesimpulan: Manifestasi klinis gigitan ular Viperidae dapat berefek pada sistem koagulasi dan jika tidak ditangani dengan tepat dapat menyebabkan gangguan sistem saraf pusat, kardiovaskular dan urogenital
DIFFUSE-WEIGHTED MAGNETIC RESONANCE IMAGING (DW-MRI) FOR CRYPTOGENIC STROKE DIAGNOSIS IN YOUNG ADULT FEMALE: A CASE REPORT Lothar Matheus Manson Vanende Silalahi
Berkala Ilmiah Kedokteran Duta Wacana Vol 5, No 1 (2020): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v5i1.165

Abstract

Background: Ischaemic stroke is caused by various aetiology. Cryptogenic stroke diagnosis is established when no aetiologies are discovered although clinical manifestations are consistent with acute stroke. Diffusion-weighted magnetic resonance imaging (DW-MRI) is one neuroimaging modalities which could be useful in exploring aetiology instead of excluding intracranial haemorrhage. There are many conflicting pieces of evidence of the benefit using DW-MRI to confirm the presence or the absence of brain lesions. Objective: To report a clinical case of ischemic stroke with negative evaluation on advanced neuroimaging studies (DW-MRI). Case Description: A female, 35 years old, presented to the emergency unit with a 6 hours history of prickling sensation before admission. There were no risk factors of stroke, and no other neurological symptoms. The neurologic examination reveals left hemihypesthesia, with normal results on laboratory examination for stroke risk factors and negative ischemic lesion on brain DW-MRI. Explorative examination on cardiac aetiologies was negative. Patient was given a standard regimen for acute stroke management despite the negative results and established as a cryptogenic stroke case. Conclusion: Diagnosis of ischemic stroke should rely mainly on clinical findings, with consideration of cryptogenic stroke when there is no aetiology found after thorough examination. Nevertheless, comprehensive examination on cardiac function and coagulation tests should be performed whenever possible to determine the cause of ischaemic stroke.
PEDIATRIC HEALTHCARE SERVICE FOR AS A PART OF INDONESIAN FUTURE Lothar Matheus Manson Vanende Silalahi
Berkala Ilmiah Kedokteran Duta Wacana Vol. 6 No. 1 (2021): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v6i1.302

Abstract

Continuing and accelerating child health are issues stated in Sustainable Development Goals (SDG) by United Nation (UN). Targets in improving child health in SDG are by decreasing neonatal and pediatric mortality. Reducing risk and prevention of neonatal mortality may be achieved by monitoring intrauterine fetal development. High burden of pediatric mortality may be seen in pediatric genetic, neoplasm and infectious disease. In this COVID-19 pandemic era, SARS-COV2 infection in children add more challenge in improving child health. In this issue, we proudly present articles on pediatric genetic, neoplasm and infectious disease especially in clinical manifestation, diagnostic and therapeutic challenge.
PERAN PEMERIKSAAN ELEKTROFISIOLOGI DALAM DIAGNOSIS SINDROM MILLER-FISHER Ahmad Asmedi; Sekar Satiti; Lothar Matheus Manson Vanende Silalahi
Callosum Neurology Vol 3 No 2 (2020): Callosum Neurology Journal
Publisher : The Indonesia Neurological Association Branch of Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (182.556 KB) | DOI: 10.29342/cnj.v3i2.104

Abstract

Sindrom Miller-Fisher merupakan salah satu varian Sindrom Guillain-Barre yang memiliki gambaran klinis unik dengan trias klasik optalmoplegia, ataksia dan arefleksia. Pemeriksaan penunjang pada Sindrom Miller-Fisher berperan penting karena beberapa kondisi penyakit juga dapat bermanifestasi seperti trias klasik Sindrom Miller-Fisher. Penunjang berupa analisis cairan serebrospinal, pencitraan otak, biomarker antibodi GQ1b telah banyak digunakan untuk menegakkan diagnosis Sindrom Miller-Fisher namun memiliki keterbatasan. Pemeriksaan elektrofisiologi kemudian banyak diteliti karena selain menunjang diagnosis dapat menjelaskan proses penyakit Sindrom Miller-Fisher. Penulisan ini bertujuan untuk membahas peran pemeriksaan elektrofisiologi dalam diagnosis Sindrom Miller-Fisher. Hasil studi menunjukkan bahwa abnormalitas amplitude Sensory Nerve Action Potential (SNAP) dan H-reflex secara konsisten terjadi pada Sindrom Miller-Fisher. Abnormalitas amplitudo SNAP akan membaik dengan cepat dan reversibel sehingga diperlukan juga pemeriksaan elektrofisiologi serial untuk dapat menunjang diagnosis Sindrom Miller-Fisher. Temuan tersebut dapat diperkuat dengan hasil pemeriksaan konduksi saraf motorik, konduksi saraf sensorik dan F-wave yang normal. Kata Kunci: Sindrom Miller-Fisher, Elektrofisiologi, Diagnosis
Co-Authors Ahmad Asmedi Alfi Rizky Medikanto Eli Rahmi Garudadwiputra, Ian A Manus, Widya Christine Sekar Satiti Sri Sutarni