Liza Meutia Sari
Department of Oral Medicine, Faculty of Dentistry, Universitas Syiah Kuala

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Catechin: Molecular mechanism of Anti-Cancer Effect: Katekin: Mekanisme Molekular Efek Antikanker Sari, Liza Meutia
Dentika: Dental Journal Vol. 22 No. 1 (2019): Dentika Dental Journal
Publisher : TALENTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (381.156 KB) | DOI: 10.32734/dentika.v22i1.683

Abstract

Over the recent decade, attention has been focused on the pathologic role of free radicals in a variety of diseases, which are most related to the carcinogenesis process. Carcinogenesis is a multi-step process that is induced primarily by carcinogens leading to the development of cancer. Extensive research in the last few years has revealed that regular consumption of certain fruits and vegetables can reduce the risk of acquiring specific cancers. Catechins are phytochemical compounds found in high concentrations in a variety of plant-based foods and beverages. Studies with cell lines have demonstrated that catechins affect signal transduction pathways, inhibit cell proliferation and induce apoptosis. More mechanistic studies in these areas will help us to understand the inhibitory action of catechin against carcinogenesis and provide background for evaluating the effects of catechin on human carcinogenesis.
Bacterial growth assessment of extraction pliers following tooth extraction in culturing bacterial on various media: a quasi-experimental study Chairunas, Chairunas; Sinta, Gian Salsabila; Sari, Liza Meutia; Suhanda, Rachmad; Zainul Abidin, Siti Nur Nabihah
Padjadjaran Journal of Dentistry Vol 36, No 2 (2024): July 2024
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol36no2.53803

Abstract

ABSTRACTIntroduction: Tooth extraction injury potentially creating an entry point for bacteria that may cause infection. Dental extraction tools that come into contact with a patient's oral cavity contain many bacteria which can be opportunistic and pathogenic. The purpose of this study was to examine the bacterial growth on tooth extraction pliers following tooth extraction in culturing bacteria on various media. Methods: Type of study is a quasi-experimental research design, using pre and post-test analysis. It was conducted in September–October 2021 at the Teeth and Mouth Dentistry Hospital (RSGM), Universitas Syiah Kuala, focusing on the swab sampling of tooth extraction pliers. The sample examination stage was conducted at the Faculty of Dentistry Laboratory. The study involved culturing bacterial on various media, including NA (Nutrient Agar), MHA (Mueller Hinton Agar), TSA (Triptic Soy Agar), TYS20B (Trypticase Soy-Yeast 20% Sukrose with Bacitracin), and performing gram staining under a microscope. Results: NA media: out of 16 samples cultured, 8 were not covered by bacteria, while the other 8 were. MHA media: all samples were overgrown with bacteria, but each 8 had different characteristics. 9 samples of TYS20B medium were overgrown with bacteria, while the other seven did not show signs of bacterial overgrowth. On TSA media, 5 samples were not overgrown with bacteria, 9 samples were overgrown with bacteria exhibiting solid, yellowish white, and not slimy, and the other 2 samples contained bacteria that were soft, yellowish white, and slimy. Conclusion: Bacillus sp., Diphtheroid basil sp., and Streptococcus mutans were found grown on the agar media.  In general, MHA media is the most effective general growth medium, while TYS20B media is the best media for Streptococcus mutans growth.
The Correlation Between the Recurrent Aphthous Stomatitis Lesion and Quality of Life Among Productive-Age Patients Sari, Liza Meutia; Rezeki, Sri; Rambe, Sarinah; Novita, Cut Fera; Herwanda, Herwanda; Fasya, Safira
Journal of Syiah Kuala Dentistry Society Vol 8, No 2 (2023): December 2023
Publisher : Dentistry Faculty

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jds.v8i2.35017

Abstract

Background: Recurrent Aphthous Stomatitis (RAS) is an ulcerative disease in oral mucosa. These lesions are usually located on the non-keratinized oral mucosa with the characteristics of recurrent ulcerated lesions and the presence of pain. Some people affected by RAS will have various impacts on speech, swallowing, and chewing functions. Patients with RAS usually experience pain, and this impact greatly affects their quality of life. Objective: This study examined the relationship between RAS and patients' quality of life. Materials and Methods: This study is a cross-sectional observational study. The method of taking the subjects was done using consecutive sampling with 32 subjects. Data collection was carried out with objective and subjective data. Results: A significant relationship exists between RAS and patient quality of life p = 0.044 (Fisher's Exact Test,p0.05). There is a significant correlation between RAS and patient quality of life Spearman's correlation test, significance p0.05) with a value of p = 0.018 with a strength level of a correlation coefficient of 0.415, which means that it has a moderate level and a direction of the correlation is positive. Conclusion: Aspects of social functioning limitation and bodily pain are most influenced by the emergence of RAS lesions. There is a positive correlation between RAS and patients' quality of life.