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All Journal Agropolitan Journal of Global Pharma Technology
Andi Emelda
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Agriculture, Biological Sciences & Forestry Chemistry Medicine & Pharmacology Other

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PENDAPATAN USAHA TERNAK SAPI POTONG DI DESA TAMBOO KECAMATAN TILONG KABILA KABUPATEN BONE BOLANGO Hadjarati Amna; Andi Emelda
Agropolitan Vol 2 No 3: Agropolitan Issue Juli 2015
Publisher : Fakultas Pertanian Universitas Ichsan Gorontalo

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Antimicrobial Activity Test of Ginseng bugis (talinum paniculatum gaertn.) Leaves Ethanol Extract against Pseudomonas aeruginosa, Propionibacterium Acnes, Streptococcus Mutans and Candida Albicans Andi Emelda
Journal of Global Pharma Technology Volume 12 Issue 10 (2020) Oct. 2020
Publisher : Journal of Global Pharma Technology

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Ginseng bugis (Talinum panicullatum Gaertn.) leaf is traditionally used in the treatment of diarrhea, ulcers, wounds and skin infections by the people of South Sulawesi province. The leaves contain chemical compounds such as saponins, alkaloids, tannins, flavonoids and triterpenes which can be a source of antioxidants and bactericidal. This study aims to determine the antimicrobial activity of ginseng bugis leaf extract against the microbes. The test microbes used were Pseudomonas aeruginosa, Propionibacterium acnes, Streptococcus mutans, and Candida albicans which has been matured. The antimicrobial activity test used agar well diffusion method with ginseng bugis leaf extract solution with a concentration variation of 0.1%; 0.5%; 1%; 2%; 4%; 8%; 16%; and 32%. The inhibition zone observations were carried out on bacteria incubated at 37oC for 24 hours and fungi incubated at 25oC for 72 hours. The results of the inhibition zone measurement showed that the higher the concentration of the test solution for the ethanol extract of ginseng bugis leaves, the greater the inhibition zone given. Based on the results, the ethanol extract of ginseng bugis leaves had antimicrobial activity at the minimum inhibitory concentration of 1% against Pseudomonas aeruginosa, Propionibacterium acne, Candida albicans and a minimum inhibitory concentration of 4% against Streptococcus mutans. Keywords: Antimicrobial, Ethanol Extract, Talinum panicullatum Gaertn.
Immunomodulator Activity and Antirheumatoid Arthritis Extract of Ethyl Acetate Ginseng Bugis Talinum Paniculatum (jacq.) Gaertn) Andi Emelda
Journal of Global Pharma Technology Volume 12 Issue 02 (2020) Feb. 2020
Publisher : Journal of Global Pharma Technology

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The Immunomodulator is one of the compounds that can improve immune system. Chemical compounds work through the immune system to prevent and treat disease. Rheumatoid arthritis is an autoimmune disease that is chronic-systemic inflammation. The purpose of this study was to determine the effects of imonomodulator and antirheumatoid arthritis of ethyl acetate extracts of ginseng bugis leaves (Talinum Paniculatum (Jacq.) Gaertn). This study was divided into 2 groups, namely the immunomodulatory testing using sheep red blood cells and CFA-induced antirhematoid. This study used wistar rats which divided into 6 groups for immunomodulatory activity and 5 groups for antirematoid arthritis. The dose of ethyl acetate extract used was 0.05 g/KgBW; 0.1 g/KgBW, and 0.15 g/KgBW. Statistical test results for immunomodulatory activity showed significantly different results between the extract group doses of 0.05 g/KgBW; 0.1 g/KgBW, and 0.15 g/KgBW (p <0.05) with a negative control group. Rheumatoid arthritis testing showed (p <0.05) to the foot volume and arthritis index. The results showed that ethyl acetate extract of ginseng bugis leaves have immunomodulatory and antirheumatoid arthritis activity.Keywords: Immunomodulator, Anti Rheumatoid arthritis, Ethyl acetate, Talinum Paniculatum (Jacq.) Gaertn.
Co-Authors Hadjarati Amna