Budapest International Research in Exact Sciences (BirEx Journal)
Vol 3, No 4 (2021): Budapest International Research in Exact Sciences, October

Initial Screening of Thyroid Function Test in Premature and Term Infants at General Hospital Dr. Zainoel Abidin Banda Aceh

Pretyca Yudra Perdana (Departement of Child Health, Faculty of Medicine, Univesitas Syiah Kuala/Zainal Abidin General Hospital, Banda Aceh, Indonesia)
Dora Darussalam (Departement of Child Health, Faculty of Medicine, Univesitas Syiah Kuala/Zainal Abidin General Hospital, Banda Aceh, Indonesia)
Rusdi Andid (Departement of Child Health, Faculty of Medicine, Univesitas Syiah Kuala/Zainal Abidin General Hospital, Banda Aceh, Indonesia)
Mulya Safri (Departement of Child Health, Faculty of Medicine, Univesitas Syiah Kuala/Zainal Abidin General Hospital, Banda Aceh, Indonesia)
Syafruddin Haris (Departement of Child Health, Faculty of Medicine, Univesitas Syiah Kuala/Zainal Abidin General Hospital, Banda Aceh, Indonesia)
Nora Sovira (Departement of Child Health, Faculty of Medicine, Univesitas Syiah Kuala/Zainal Abidin General Hospital, Banda Aceh, Indonesia)



Article Info

Publish Date
14 Oct 2021

Abstract

Congenital hypothyroidism (CH) is the most common cause of mental retardation which can be prevented by early diagnosis and treatment. Premature infants have a higher risk of developing HK than term infants. Screening for CH in every newborn is important, however, in premature babies screening for CH using the TSH examination is often found to have normal levels in the first week of examination. This study is a cross sectional study where the research sample amounted to 62 infants who were divided into 2 groups, namely premature babies (n = 31) and term infants (n = 31). Statistical analysis used is Independent sample t test and Mann-Whitney U test. This study aims to assess the comparison of thyroid function (FT4 and TSHs) between premature infants and term infants at the first examination in the age range of 2 -6 days. The results showed that 90% (28/31) premature infants had hypothyroxinemia with lower FT4 levels than term infants (18.70 ± 6.50, 95% CI). TSHs levels in premature infants were higher than term infants (5.70 ± 5.27, 95% CI). This study concluded that FT4 is better at detecting thyroid function disorders in premature infants while TSHs are better at detecting abnormal thyroid function in term infants.

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Journal Info

Abbrev

birex

Publisher

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Physics Transportation

Description

Budapest International Research in Exact Sciences (BirEx-Journal) is a peer reviewed journal published in January, April, July, October welcome research paper in Medical Science, Agriculture Science, Biological Science, Engineering Science and other related areas and it is published in both online ...