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All Journal Jurnal Farmasi Higea

Fitra Fauziah

Sekolah Tinggi Ilmu Farmasi (STIFARM) Padang

Author-ID : 3768674

Medicine & Pharmacology

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Penetapan Kadar Vitamin B1 Pada Kacang Kedelai dan Tempe Yang Beredar di Pasar Raya Padang Secara Spektrofotometri Visibel Fitra Fauziah; Roslinda Rasyid; Angga Prawina Akbar
Jurnal Farmasi Higea Vol 8, No 1 (2016)
Publisher : STIFARM Padang

It has been the research about determination level of vitamin B1 in soy bean and tempe. The determination level of vitamin B1 was measured by spectrophotometry visible method. The result is level of vitamin B1 in soy bean higher than level of vitamin B1 in tempeh. Which level of vitamin B1 in soy bean and tempeh is about 1.0213 % ±0.0188% and 0.2960 % ±0.0095%. It show that the proces manufacturing, like washing, bathing, boiling can affect the level of vitamin B1. Statistic analyze anova one way by using SPSS 17 program shows there are significant different (p<0.05) in the level from each sample.

Pengaruh Ekstrak Etanol Daun Belimbing Wuluh (Averrhoa Bilimbi L.) Terhadap Kadar Kolesterol Total Dan LDL Pada Mencit Putih Jantan Hiperkolesterolemia Fitra Fauziah; Rahimatul Uthia; Melani Musdar
Jurnal Farmasi Higea Vol 10, No 2 (2018)
Publisher : STIFARM Padang

VALIDASI METODE ANALISIS Α-MANGOSTIN DALAM PLASMA DARAH MANUSIA SECARA IN VITRO DENGAN KROMATOGRAFI LAPIS TIPIS-DENSITOMETRI Fitra Fauziah; Widya Kardela; Roslinda Rasyid; Multi Silvi
Jurnal Farmasi Higea Vol 9, No 2 (2017)
Publisher : STIFARM Padang

Penelitian ini dilakukan bertujuan untuk memvalidasi metode analisis penetapan kadar α-mangostin dalam plasma darah manusia secara in vitro dengan metode KLT-densitometri. α-Mangostin diekstraksi dari plasma yang sebelumnya ditambahkan dengan larutan α-mangostin dengan metode pengendapan protein menggunakan metanol sehingga diperoleh supernatannya. Pemisahan dilakukan dengan KLT dengan fase diam silika gel 60 F254 dan fase gerak kloroform : etil asetat (9 : 1), kemudian dilakukan scanner dengan densitometri. Validasi metode analisis menunjukkan bahwa metode ini memenuhi persyaratan parameter validasi. Akurasi diperoleh rata-rata persen perolehan kembali yaitu 96,0591%, presisi intraday dari konsentrasi 50 ppm, 100 ppm dan 150 ppm diperoleh rata-rata persen RSD yaitu 1,6440%, 2,1993% dan 1,6389%, presisi interday yaitu 2,8533%, 1,4208%, 3,0985%, linearitas yaitu 0,9922, batas deteksi yaitu 37,8323 ppm dan batas kuantitasi yaitu 110,8014 ppm. Hasil penetapan kadar α-mangostin dalam plasma darah manusia yang sebelumnya ditambahkan dengan larutan α-mangostin secara invitro dari kadar sampel 120 ppm yaitu 115,2709 ± 3,7990 ppm

Pembuatan Kafein Benzoat Secara Semisintetis Dari Serbuk Teh Kayu Aro Fitra Fauziah; Zulharmita Zulharmita; Wahyu Ningsih
Jurnal Farmasi Higea Vol 9, No 1 (2017)
Publisher : STIFARM Padang

Caffeine benzoate semisynthetis had been create from tea powder which produced by PTP Nusantara VI Kayu Aro, District of Kerinci, Province of Jambi. Caffeine was isolated from 25 grams of tea powder by fractionated and crystallized to obtained 102 mg of caffeine crystals. Caffeine crystals isolated as much as 50 mg was reacted with 32 mg of benzoic acid the result was 30 mg of caffeine benzoate. Caffeine benzoate was characterized which organoleptic form was fine powder, greenish-white color, bitter taste, and distinctive odor. Melting point was 196 oC. Infrared spectrum showed group O-H at wave number 2700-2500 cm-1, which it did not show on spectrum caffeine crystals. The maximum absorption wavelength was obtained 273.5 nm. Profile of thin-layer chromatography which stationary phase silika gel 60 F254 and mobile phase chloroform : ethanol (99:1) was obtained Rf value 0.35.

Pengaruh Proses Pengolahan Terhadap Kadar Beta Karoten Pada Ubi Jalar Varietas Ungu (Ipomoea Batatas (L.) Lam) dengan Metode Spektrofotometri Visibel Fitra Fauziah; Roslinda Rasyid; Reza Fadhlany
Jurnal Farmasi Higea Vol 7, No 2 (2015)
Publisher : STIFARM Padang

Purple sweet potato (Ipomoea batatas) is one of the agricultural commodities as source of carbohydrates and energy which is included in the family of Convolvulaceae. It is also a good source of vitamins and minerals which is good for nutrition and health. One of the compounds contained in purple sweet potato is beta-carotene. Beta-carotene is a precursor of vitamin A. It is useful as an antioxidant, boosts the immune system and treats other diseases. Beta-carotene is unstable, especially at high temperature. This study aims at answering the question as to how the processing of purple sweet potato can effect to beta-carotene level by using Visible spectrophotometry method. This study is conducted by performing three treatments to purple sweet potato i.e. raw, fried and boiled sample. Weight of raw sample is 10 grams, fried and boiled sample is 15 grams. The sample were extracted by liquid-liquid extraction and it is measured by Visibel spectrophotometer at maximum wavelength of 452.5 nm. The results obtained show that the average level of beta-carotene is 75.91 ±1.92 ppm for raw samples, 63.05 ± 3.45 ppm for fried, and 45.66 ± 0.82 ppm for boiled. The result is statistically calculated by one-way ANOVA statistical analysis. It shows that sig 0.000 (P < 0.05), and it indicates that there is an effect of processing to the average level of beta-carotene contained in purple sweet potato.

Co-Authors Angga Prawina Akbar Melani Musdar Multi Silvi Rahimatul Uthia Reza Fadhlany Roslinda Rasyid Wahyu Ningsih Widya Kardela Zulharmita Zulharmita

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