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Eka Syuryani
Sekolah Tinggi Ilmu Farmasi (STIFARM) Padang
Medicine & Pharmacology

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Perbandingan Kemampuan Polimer HPMC dengan Gom Arab dalam Meningkatkan Kecepatan Disolusi Tablet Karbamazepin Rina Wahyuni; Auzal Halim; Eka Syuryani
Jurnal Farmasi Higea Vol 7, No 1 (2015)
Publisher : STIFARM Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (777.262 KB) | DOI: 10.52689/higea.v7i1.113

Abstract

The effect of HPMC and gom arabic to do dissolution ability of carbamazepine tablets made by wet granulation has been. There are 5 formulas of carbamazepine granules, mind each formula was containing 40% w/w of carbamazepine. Carbamazepine wese coated by HPMC polymers and gom arabic by spray drying process. formula 0 countain carbamazepine with coanted HPMC and  gom arabic witle formula 1 and 2 is countain carbamazepine coated by HPMC polymers with  concentration 5% w/w and 10% w/w respectively. Formula 3 and 4 is countain  carbamazepine which counted by gom arabic with  concentration 5% and 10% respectively. The result shows that formula 2 show the highest dissolution rate 134.7133%.
Co-Authors Auzal Halim Rina Wahyuni