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Analisis Farmakoterapi Pada Pasien Henoch-Schönlein Purpura dan Hematokezia Husnawati Husnawati; Melia Oktavia; Dessy Novita Sari; Puji Kurniawati
Jurnal Pendidikan Tambusai Vol. 10 No. 2 (2026): Agustus
Publisher : LPPM Universitas Pahlawan Tuanku Tambusai, Riau, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jptam.v10i2.41029

Abstract

Henoch-Schönlein Purpura (HSP) merupakan vaskulitis pembuluh darah kecil yang sering terjadi pada anak dan dapat menyebabkan manifestasi gastrointestinal berupa hematokezia.. Penelitian ini bertujuan untuk mengetahui gambaran klinis, terapi farmakologis, serta peran apoteker dalam pemantauan terapi obat pada pasien anak dengan diagnosis HSP dan hematokezia di bangsal anak Rumah Sakit X. Pasien laki-laki usia 15 tahun dengan berat badan 40 kg datang dengan keluhan nyeri perut kanan bawah, BAB berdarah, mual muntah, demam, sesak napas, nyeri pada kedua lutut, mata merah, dan purpura pada kedua tungkai serta tangan. Terapi yang diberikan meliputi methylprednisolone, omeprazole, ceftriaxone, ondansetron, tranexamic acid, phytomenadione, paracetamol, dan cairan infus KA-EN 1B. Hasil evaluasi menunjukkan terapi dan dosis sudah sesuai, tanpa interaksi obat atau alergi, namun masih terdapat potensi Drug Related Problems (DRP) berupa risiko efek samping gastrointestinal dan perlunya terapi diare.
Analisis Rasionalitas Penggunaan Antibiotik Profilaksis Pada Pasien Bedah Sesar Husnawati - Husnawati
JURNAL FARMASI DAN MAKANAN Vol 5 No 2 (2022): Journal Of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v5i2.2404

Abstract

Prophylactic antibiotics are antibiotics given before, during and up to 24 hours postoperatively in cases where clinically there are no signs of infection, but prophylactic antibiotics are given to prevent surgical site infections, including cesarean section. The purpose of this study was to examine the rationale for the use of prophylactic antibiotics in cesarean section at a PMC hospital Pekanbaru. This type of research is a qualitative study, using descriptive methods and data obtained from medical records retrospectively, using purposive sampling technique on 69 medical records that meet the inclusion criteria. The results showed that the use of prophylactic antibiotics at cesarean section was 66.67% rational and 33.33% irrational. The measured rationality is the right indication (100%), right drug (100%), right patient (100%), right regimen (right dose (95.61%), right frequency (79.82%), right time of administration (100%), the right way of administration (100%) given intravenously), and alert for side effects (100%)
Pola Penggunaan Obat Antipsikotik pada Pasien Skizofrenia di Puskesmas Rawat Jalan Alah Air Kabupaten Kepulauan Meranti Husnawati - Husnawati
JURNAL FARMASI DAN MAKANAN Vol 6 No 1 (2022): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v6i1.2755

Abstract

The high number of schizophrenic patients at the Puskesmas Alah Air needs attention, one of which is the pattern of treatment. This study aims to determine the pattern of the use of antipsychotic drugs at the Puskesmas Alah Air, Tebing Tinggi District, Kepulauan Meranti. This research is an observational study with a descriptive design. The data source in this study was patient medical record data during January to December 2021 at the Puskesmas Alah Air. The study sample was 81 patients who met the inclusion criteria. The results showed that the majority of schizophrenic patients were male (74.1%), with an early adult (18-40) year as many as 60.5%. Based on the most widely used antipsychotic drugs, the typical antipsychotic group with halloperidol was 71.6%. Based on the route of administration, 100% of the drugs were given orally. Based on the generic name and trade name, 100% of the drugs used are generic. Based on single and combination therapy, the results obtained are combination therapy, which is 90.1% and the most combinations are typical antipsychotics with typical. The conclusion of this study shows that the pattern of drug use is to use a typical generic antipsychotic orally in a combination form
Tingkat Kepatuhan Minum Obat Pada Pasien Hipertensi Berdasarkan Sosiodemografi di Salah Satu Puskesmas di Kota Pekanbaru Husnawati - Husnawati
JURNAL FARMASI DAN MAKANAN Vol 7 No 1 (2023): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v7i1.3882

Abstract

Hypertension is a chronic disease that cannot be cured, but can be controlled and requires long-term or even lifelong treatment. Hypertension drugs must be taken regularly to control blood pressure and avoid the risk of complications. An important factor in achieving successful hypertension therapy is adherence. Conversely, non-adherence is one of the main factors causing therapy failure. This study aims to determine the level of medication adherence in hypertensive patients at one of the community health centers in Pekanbaru city. This research is an observational study with a descriptive research design using concurrent data collection techniques. The sampling technique in this study was carried out non-randomly using purposive sampling method. The sample in this study were 105 respondents who met the inclusion criteria. The results showed that most of the respondents were aged 41-60 years (middle adults), female, with junior high school education levels (secondary education) and unemployed employment status. The level of adherence in terms of gender and employment status did not differ much, but based on age and level of education, the older the age and the higher the level of education, the higher the level of adherence
Pengaruh Video Edukasi Penggunaan Suplemen Kesehatan saat Pandemi Covid-19 terhadap Tingkat Pengetahuan Masyarakat di Kecamatan Binawidya Pekanbaru Husnawati - Husnawati; R. Pebliana Syahara; Seftika Sari; Putri Lestari
JURNAL FARMASI DAN MAKANAN Vol 7 No 2 (2024): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v7i2.4513

Abstract

The significant increase in confirmed cases of COVID-19 necessitates the implementation of preventive measures by the general public to mitigate the risk of contracting the disease. One strategy that can be employed involves the consumption of health supplements. Among the most prevalent health supplements consumed by the public during the COVID-19 pandemic is vitamin C, which is taken to enhance immunity as part of the preventive measures against COVID-19. This research aims to see the effect of providing educational videos on the use of health supplements during the COVID-19 pandemic on the level of community knowledge in the Binawidya sub-district of Pekanbaru. This research is a quasi-experimental research with a non-randomized control group pretest-posttest design with data collection techniques, namely purposive sampling using a Google form questionnaire. In this research, the sample consisted of individuals from the Binawidya sub-district who met the inclusion criteria, totaling 100 respondents. The analysis of the knowledge data revealed a significant impact of educational videos on the utilization of health supplements amidst the COVID-19 pandemic, as evidenced by an obtained P value of 0.000, which is less than the predetermined significance level of 0.05.
Analisis Kepatuhan Minum Obat dan Outcome Terapi pada Pasien Hipertensi di Puskesmas Se-Kabupaten Bengkalis : Analysis of Medication Adherence and Therapeutic Outcome in Hypertension Patients at Public Health Centers in Bengkalis Regency Husnawati - Husnawati; Syilfia Hasti; Rizki Abi Rahman
JURNAL FARMASI DAN MAKANAN Vol 8 No 2 (2025): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v8i2.5872

Abstract

Hypertension is a chronic disease and cannot be cured, but it can be controlled. One of the determining factors for the success of hypertension treatment is medication adherence to avoid complications. The level of adherence to antihypertensive varies among patients. The aim of this study is to analyze medication adherence and therapeutic outcome in hypertensive patients at health centers throughout Bengkalis Regency. This observational study uses a cross-sectional design with a descriptive-analytic method. The sample in this study consisted of 120 respondents who met the inclusion criteria, and the sampling technique was conducted using non-probability purposive sampling. This study was conducted at health centers across Bengkalis Regency, with five health centers serving as data collection sites. Based on this study, it was found that the majority of respondents (43.3%) had low adherence and only 37.5% achieved desired outcome. Based on the results of the Chi-Square test, it can be concluded that there is a relationship between medication adherence and therapeutic outcome in hypertensive patients at health centers throughout Bengkalis Regency, with a p-value of 0.001.
Analisis Perbandingan Implentasi Cara Distribusi Obat Yang Baik (CDOB) Pada Pedagang Besar Farmasi (PBF) BUMN Dan Non BUMN Di Wilayah Provinsi Riau Suci Amaliya Indah Lestari Suci Amaliya Indah Lestari; Husnawati Husnawati; Seftika Sari
JURNAL FARMASI DAN MAKANAN Vol 9 No 1 (2025): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v9i1.6711

Abstract

Drug distribution is a crucial step in ensuring the quality, safety, and availability of drugs in the community. Good Drug Distribution Practices (CDOB) are established as a standard by the Food and Drug Monitoring Agency (BPOM) for all Pharmaceutical Wholesalers (PBF). This study aims to compare the implementation of CDOB in state-owned and non-state-owned PBFs in Riau Province. The study used a mixed methods study approach. The research design used Sequential Explanatory by combining quantitative and qualitative methods. The quantitative approach used a cross-sectional design with instruments in the form of a CDOB checklist consisting of 12 CDOB aspects and in-depth interviews with Responsible Pharmacists (APJ). Quantitative data analysis was carried out by calculating the percentage (%) of conformity based on the results of the BPOM CDOB checklist form and the Chi-Square test. Qualitative data analysis was conducted descriptively through interviews using content analysis methods to identify discrepancies in the results of the BPOM CDOB checklist and to identify factors influencing CDOB implementation in state-owned and non-state-owned enterprises (BUMN) PBFs. The results showed that the overall compliance level of CDOB implementation reached 99.6% of the maximum score, with an average score of 114.5 out of a total score of 115. BUMN and non-BUMN PBFs achieved the same average score of 114.5/115 (99.6%). Almost all aspects of CDOB were implemented well, but BUMN PBFs still faced deficiencies in organizational and personnel aspects related to personnel discipline. Meanwhile, non-BUMN PBFs faced major challenges in buildings and equipment, particularly limited storage space and temperature control in cool rooms. A chi-square test showed no significant difference between BUMN and non-BUMN PBFs (p > 0.05). Factors influencing CDOB implementation include: competence and human resources, quality management systems, adequate facilities and infrastructure, and compliance with SOPs and regulations. In conclusion, the implementation of CDOB in state-owned and non-state-owned enterprise (BUMN) PBFs in Riau Province has been very successful, with a compliance rate of >99%. Although strengthening of human resources and storage infrastructure is still needed to ensure the quality of sustainable drug distribution.
Hubungan Faktor Terapi Dengan Tingkat Kepatuhan Pnggunaan Obat Pasien Systemic Lupus Erythematosus (SLE) Di Rumah Sakit Umum Daerah Arifin Achmad Provinsi Riau Husnawati - Husnawati; Novia Sinata; Maya Sari
JURNAL FARMASI DAN MAKANAN Vol 9 No 2 (2026): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v9i2.7587

Abstract

Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease that requires long-term therapy to control symptoms and prevent organ damage. This study aims to determine the relationship between therapy factors and the level of compliance in SLE patients using the chi-square test with a sample of 64 respondents selected by purposive sampling. The research instrument, the MGLS questionnaire, was used to assess patient compliance. The results showed that the duration of treatment and drug side effects had a significant relationship (P<0.05) with the level of compliance, while the complexity of treatment did not have a significant relationship with the level of compliance (P>0.05). This study indicates that drug side effects are one of the important factors influencing the compliance of SLE patients with therapy
Analisis Komparatif Sosiodemografi Terhadap Kepatuhan Penggunaan Antihipertensi Pada Pasien Hipertensi RSUD Puri Husada Tembilahan Husnawati Husnawati; Erniza Pratiwi; Yellia Syafitri; Cindy Oktaviana Laia; Reni Zulfitri
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 18 No 1 (2026): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfionline.v18i1.240

Abstract

Hypertension is a condition where systolic blood pressure increases to more than 140 mmHg and diastolic blood pressure to more than 90 mmHg. Compliance with antihypertensive medication is crucial. Hypertension cannot be cured and must be consistently monitored to prevent complications that can lead to death. One of the factors that can affect the level of medication adherence in patients is the patient's sociodemographics including age, gender, educational level and employment status. The purpose of this study was to analyze the effect of sociodemography on compliance with antihypertensive use in hypertensive patients at Puri Husada Tembilahan Hospital. This research is an observational study with a cross-sectional research design with analytic descriptive method. The sample in this study were patients with a primary diagnosis of hypertension with or without comorbidities who went to the Puri Husada Tembilahan Hospital at the time of the study and met the inclusion criteria. Based on the results of the study it was found that of the 4 sociodemographic aspects studied, namely age, gender, education level and employment status, only education level affected the level of adherence to taking medication in hypertensive patients (P value = 0.000), where respondents with higher education levels had higher levels of higher adherence than respondents with low levels of education.
Analisis Faktor Risiko Penggunaan Obat Anti-Inflamasi Nonsteroid Jangka Panjang terhadap Penyakit Ginjal Kronik di RSUD Arifin Achmad Provinsi Riau Septi Muharni; Syilfia Hasti; Rizka Meidhika; Fina Aryani; Husnawati Husnawati
JPSCR: Journal of Pharmaceutical Science and Clinical Research Vol 10, No 2 (2025)
Publisher : Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/jpscr.v10i2.59263

Abstract

Penyakit ginjal kronis merupakan masalah kesehatan global dengan angka kejadian yang terus meningkat, memiliki prognosis yang buruk dan banyak menghabiskan biaya dalam perawatannya. Salah satu faktor risiko penyakit ginjal kronikadalah penggunaan obat Anti Inflamasi Nonsteroid (AINS) jangka panjang. AINS bekerja dengan menghambat enzim COX-1 yang berperan dalam mempertahankan perfusi ginjal. Penghambatan ini mengakibatkan terganggunya fungsi ginjal (autoregulasi ginjal) jika digunakan rutin dan dalam jangka waktu panjang, terutama pada pasien dengan faktor risiko seperti pasien hipertensi, gangguan fungsi ginjal dan pasien lanjut usia. AINS sangat mudah diperoleh masyarakat tanpa resep dokter dan menjadi salah satu risiko penggunaan yang tidak rasional. Penelitian ini bertujuan untuk mengetahui hubungan dan kekuatan hubungan antara riwayat penggunaan AINS, frekuensi dan lama penggunaan terhadap kejadian penyakit ginjal kronik. Penelitian ini dilakukan dengan pendekatan case control pada 100 pasien (50 kasus penyakit ginjal kronikdan 50 kasus non penyakit ginjal kronik) di Poli Penyakit dalam RSUD Arifin Achmad Provinsi Riau dengan teknik purposive sampling. Hasil uji statistik menunjukkan riwayat penggunaan AINS, frekuensi, dan lama penggunaan tidak memiliki hubungan yang signifikan terhadap kejadian penyakit ginjal kronik(nilai p&gt;0,05) dengan odds ratio (OR) 2,19; 0,33 dan 0,556. Meskipun tidak bermakna secara statistik, hasil ini menunjukkan adanya kecenderungan peningkatan risiko penyakit ginjal kronik pada pasien yang memiliki riwayat penggunaan AINS jangka panjang.