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All Journal YARSI Medical Journal Sinnun Maxillofacial Journal Yarsi Dental Journal
Fazwishni Siregar
Department of Oral Biology, Faculty of Dentistry, Universitas Indonesia, Jakarta 10430
Dentistry Health Professions Materials Science & Nanotechnology Medicine & Pharmacology Public Health

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Cytotoxicity of Physic Nut (Jatropha curcas L., Euphorbiaceae)Latex by Agar-Overlay Siregar, Fazwishni
Jurnal Kedokteran YARSI Vol 23, No 3 (2015): SEPTEMBER - DESEMBER 2015
Publisher : Lembaga Penelitian Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (146.833 KB) | DOI: 10.33476/jky.v23i3.229

Abstract

Jatropha curcas L. latex has been used as traditional medicine to cure various infections among others are to cure toothache, apthae, as a mouth rinse to treat bleeding gums, as a hemostatic, and a wound dressing. To be used as herbal medicine, scientific investigation including toxicological studies must be conducted. The aim of these studies was to evaluate the cytotoxicity of J. curcas latex by agar overlay technique as part of toxicological study. Fibroblasts L929 were cultured in Petri dishes to confluence, and a layer of agar was then added. After staining the cells with neutral red, diluted latex (0.4-15% w/v) imbibed in filter paper were applied to the agarsurface and incubated for 24 hours. Evaluation was based on the zone of decoloration and lysis indices. Result showed that there was zone of decoloration from 2-5 mm in diameter that was all in the index 2 (less than 5 mm) from 5 index decoloration classification. Lyses cells were not observed in the decoloration zone, which could be interpreted as a coagulative necrosis. It may be concluded thatJ. curcaslatex has a moderate cytotoxic activity and necrotic coagulation in an agar-overlay technique usingfibroblast L929.
Evaluasi Analisis Howes dan Korkhaus Pada Model Studi Mahasiswa Fakultas Kedokteran Gigi Universitas Yarsi Maharani, Qanita Regina; Siregar, Fazwishni; Ardinansyah, Agus
Sinnun Maxillofacial Journal Vol. 6 No. 01 (2024): April 2024
Publisher : Fakultas Kedokteran Gigi Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/smj.v6i01.139

Abstract

Latar belakang: Analisis model studi Howes dan Korkhaus digunakan sebagai alat bantu untuk menegakkan diagnosis dan rencana perawatan ortodontik. Setiap analisis model studi memiliki standar nilai normal yang didapatkan dari hasil pengukuran dan perhitungan pada ras Caucasoid, namun terdapat perbedaan hasil standar nilai normal pada ras atau etnis yang berbeda sehingga penggunaan analisis Howes dan Korkhaus perlu dikaji lebih lanjut terhadap gigi geligi pada model studi orang yang berasal dari ras yang berbeda. Tujuan: Penelitian ini bertujuan untuk mengetahui evaluasi analisis model Howes dan Korkhaus pada mahasiswa Fakultas Kedokteran Gigi Universitas YARSI (FKG YARSI) dan hasilnya akan dibandingkan dengan penelitian analisis Howes dan Korkhaus pada populasi lainnya. Metode penelitian: Jenis penelitian ini menggunakan metode analitik deskriptif crosssectional. Sampel diambil pada populasi mahasiswa FKG YARSI dan dipilih berdasarkan kriteria inklusi dan eksklusi yang telah ditentukan. Total sampel sebanyak 22 model studi mahasiswa FKG YARSI yang terdiri dari 18 perempuan dan 4 laki-laki. Model studi dibuat dengan cara mencetak subjek menggunakan alginat dan melakukan pengecoran menggunakan gipsum, lalu dilakukan pengukuran, perhitungan, serta dianalisis secara statistik menggunakan SPSS. Hasil: Hasil analisis Howes mahasiswa FKG YARSI 46,40%, panjang lengkung anterior Korkhaus 162,23 dan tinggi palatum Korkhaus 37,86%. Terdapat perbedaan bermakna pada nilai analisis howes dan tinggi palatum Korkhaus mahasiswa FKG YARSI dibandingkan dengan standar normal Ras Caucasoid, namun tidak ada perbedaan bermakna pada panjang lengkung anterior Korkhaus. Dibandingkan dengan penelitian lain terdapat perbedaan dan persamaan sesuai dengan karakteristik ras setiap populasi. Kesimpulan: Adanya variasi ukuran gigi geligi, lengkung gigi, dan tinggi palatum pada setiap individu menyebabkan perbedaan hasil indeks Howes dan Korkhaus, sehingga penggunaan standar normal pada setiap analisis model studi harus disesuaikan kembali pada masing-masing populasi.
Evaluation of Cephalometric Downs Analysis on Cephalograms at RSGM YARSI, Jakarta Puspitasari, Ayu Laksmi; Siregar, Fazwishni
YARSI Dental Journal Vol. 1 No. 2 (2024): YARSI DENTAL JOURNAL
Publisher : Lembaga Penelitian Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33476/ydj.v1i2.166

Abstract

Introduction: Cephalometric analysis is used to help establish diagnosis and treatment plan in orthodontics. One of the cephalometric analysis is the Downs analysis which its standard values were measured in Caucasians. However, these values cannot be applied to other races and ethnicities because there are racial and ethnic variations. Hence, it is necessary to know the average value for Indonesians. Objective: This study aimed to evaluate Downs analysis on cephalograms at RSGM YARSI Jakarta, compare it with Downs’ norms and other ethnicities, and determine differences between gender. Materials and Methods: Measurements of 10 parameters of Downs analysis were carried out on 29 cephalograms. Data were tested statistically. Results: The mean of the facial angle are 85.17°±3.07; angle of convexity 3.62°±2.79; AB plane angle AB -2.65°±2.55; mandibular plane angle 29.82°±3,37; Y-axis 64.15°±3.34, occlusal plane angle 11°±2.86; interincisal angle 113.06°±7.64; LI-occlusal angle 28.41°±5.24; IMPA angle 10.24°±5.76; distance of UI-APog 8.05 mm±1.85. Discussion: The RSGM YARSI cephalometric value compared to the Downs’ norms shows that the chin towards the FHP is more retroposition, the face is more convex, the relationship of the lower and upper jaw to the NPog is more protrusive, the direction mandibular growth towards the FHP is more vertical, the direction of facial growth is more downward, occlusal growth towards the FHP is steeper, and the incisors are more protruded. The direction of growth in male is more vertical than in female, and there are differences in cephalometric values with other races. Conclusion: There is a significant difference between the Downs cephalometric values of RSGM YARSI and the Downs’ norms in all measurements. Between men and women at RSGM YARSI there are gender differences in the direction of growth. There are differences in measurement values with other races.
Relationship Between Perception of Dental and Smile Aesthetics and Adolescent Self-Confidence in Jakarta Delima, Anita Rosa; Maheswari, Rifda Zhafira; Solachuddin, Ar Razi Ryoshi; Siregar, Fazwishni
YARSI Dental Journal Vol. 3 No. 1 (2025): YARSI DENTAL JOURNAL
Publisher : Lembaga Penelitian Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33476/ydj.v3i1.316

Abstract

Introduction: Adolescents are unique individuals who go through different phases of psychological development and identity from childhood to adulthood. In this period, adolescents have an important part in their lives, namely self-confidence. This can be seen when the teenager begins to pay attention to the condition of his teeth and smile. Objectives: This research was conducted to examine the relationship between the perception of the aesthetics of teeth and smile with the self-confidence of adolescents in Jakarta by using a random sampling research method. Material and Methods: This research is quantitative with a cross-sectional study. Results: The results indicate that there are still many teenagers in Jakarta who feel less confident about the aesthetics of their teeth and smile. Discussion: A significant positive correlation was found between perception of dental and smile aesthetics and adolescent self-confidence, with females showing greater concern for appearance. Conclusion: It can be concluded that the perception of the aesthetics of teeth and smile affects the self-confidence of the teenager.
Co-Authors Ardinansyah, Agus Delima, Anita Rosa Maharani, Qanita Regina Maheswari, Rifda Zhafira Puspitasari, Ayu Laksmi S.M. M.S. Akbar Siti M. S. Akbar Solachuddin, Ar Razi Ryoshi