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All Journal Indonesian Journal for Health Sciences (IJHS) Jurnal Riset Kesehatan Poltekkes Depkes Bandung Jurnal Pengabdian Masyarakat Kesehatan Indonesia
Asep Dermawan
Poltekkes Kemenkes Bandung
Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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ANALISIS POTENSI ANTIBIOTIKA BERDASARKAN KONSENTRASI HAMBAT MINIMAL DAN KONSENTRASI BAKTERISIDAL MINIMAL KLORAMFENIKOL DAN AMOKSISILIN TERHADAP SALMONELLA TYPHI Deny Rudiansyah; Asep Dermawan; Yuliansyah Sundara Mulia
JURNAL RISET KESEHATAN POLTEKKES DEPKES BANDUNG, Online ISSN 2579-8103 Vol 13 No 1 (2021): Jurnal Riset Kesehatan Poltekkes Depkes Bandung
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (576.431 KB) | DOI: 10.34011/juriskesbdg.v13i1.1842

Abstract

Infectious sicknesses are as yet one of the medical issues on the planet, including Indonesia. Different sorts of anti-toxins have been utilized to treat irresistible sicknesses. One illustration of an irresistible sickness brought about by microorganisms is typhoid fever or enteric fever brought about by Salmonella typhi (S.typhi.). Since 1948, chloramphenicol has been the medication of decision for S.typhi contamination. Objective: To think about and decide the anti-microbial power of chloramphenicol and amoxicillin against S.typhi. Exploration is expected to discover other anti-infection treatment alternatives that are more touchy. One of them is by directing this examination with the KHM and KBM tests. Methods: To see the potential for anti-microbials, the Minimum Inhibitory Concentration (MIC) was tried utilizing the cylinder weakening strategy and the Minimum Kill Concentration (KBM) utilizing the Kirby Bauer technique. This examination is a kind of in vitro lab test research. Information examination utilizing SPSS application with Mann Whitney U Test. Results: The examination showed that chloramphenicol had anti-infection power with a MIC worth of 12.50 g/ml, while amoxicillin had anti-infection potential with a MIC worth of 6.25 g/ml. The MBC an incentive for chloramphenicol and amoxicillin has a similar worth of 25 g/ml. Conclusion: There is no distinction in MIC and MBC esteems ​​between the anti-toxins chloramphenicol and amoxicillin against S.typhi. Amoxicillin can be utilized as an elective medication for the treatment of typhoid fever disease.
PEMBERDAYAAN LARVA (Maggot black soldier fly) DALAM MENGOLAH SAMPAH ORGANIK DI DAERAH RW 12 & RW 04 KELURAHAN CITEUREUP CIMAHI UTARA Iis Kurniati; Asep Dermawan; Nina Marliana
Jurnal Pengabdian Masyarakat Kesehatan Indonesia Vol. 1 No. 1 (2022): Jurnal Pengabdian Masyarakat Kesehatan Indonesia
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jpmki.v1i1.969

Abstract

Garbage is a serious problem and has not been utilized optimally. Therefore, it is necessary to find a solution so that organic waste can be minimized and become more useful. One of the efforts that can be applied in the Rw 12 and Rw 04 areas, Citeureup Village, North Cimahi, is bioconversion using larvae (Maggot black soldier fly). BSF larvae with their ability to degrade organic waste are used to convert organic matter so that they have economic potential. Garbage is the residual waste from a product or item that is no longer used, but can still be recycled into valuable goods. Meanwhile, organic waste is waste that comes from the rest of living things that can easily decompose naturally without human intervention. Organic waste can be regarded as environmentally friendly waste and even waste can be reprocessed into something useful if managed properly. However, if this organic waste is not managed properly, it will cause disease and an unpleasant odor which is the result of the rapid decomposition of organic waste. The method offered is technology transfer through counseling, training and mentoring. The expected result of this research is an increase in the knowledge, skills of partners about the bioconversion of waste using BSF larvae, as well as obtaining other additional products in the form of organic vegetables obtained from cultivation using biodegradable waste commonly called maggot (kasgot) and organic catfish that are fed using maggot, so this activity can help in efforts to improve family nutrition.
Comparison Of Middlebrook 7H9 Culture and Xpert MTB/XDR for Detecting Isoniazid and Fluoroquinolone Resistance Rika Rostikawati; Hafizah Ilmi Sufa; Oos Fatimah Rosyati; Asep Dermawan
Indonesian Journal of Health Science Vol 10 No 02 (2026): September
Publisher : Universitas Muhammadiyah Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24269/ijhs.v10i02.13441

Abstract

Drug-resistant tuberculosis (DR-TB) remains a major public health challenge in Indonesia, necessitating rapid and accurate detection of resistance to key anti-tuberculosis drugs. This quantitative descriptive analytic cross-sectional study evaluated the concordance of Mycobacterium tuberculosis resistance detection between phenotypic Middlebrook 7H9 liquid culture and genotypic TCM XDR in 44 DR-TB patients, focusing on isoniazid (H) and fluoroquinolone/levofloxacin (FQ/Lfx) resistance. Data were analyzed using the McNemar test methode. High-concentration H resistance was detected in 68.2% by culture and 65.9% by TCM XDR, while FQ/Lfx resistance was identified in 18.2% and 15.9%, respectively. No significant differences were observed between methods for high-concentration H and FQ/Lfx resistance detection (P=1.000), indicating high concordance with cappa values 0,74 isoniazid for and 0,86 for FQ/Lfx resistance. In contrast, a significant discrepancy was found for low-concentration H resistance (P=0.001), with a discordance rate of 25%, potentially attributable to HA promoter mutations not included in the TCM XDR panel or non-genetic adaptive mechanisms.
Co-Authors Deny Rudiansyah Hafizah Ilmi Sufa Iis Kurniati Nina Marliana Oos Fatimah Rosyati Rika Rostikawati Yuliansyah Sundara Mulia