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All Journal Proceedings of the International Conference on Applied Science and Health Jurnal EduHealth
Atik Sutisna
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Education Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

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THE INHIBITION TEST OF FLAVONOID AND TANNIN IN NONI FRUIT (Morinda citrifolia Linn) COMPARED TO CEFTRIAXONE TOWARDS Escherichia coli IN VITRO Tessa Swesty Islamia; Atik Sutisna; Hikmah Fitriani
Proceedings of the International Conference on Applied Science and Health No. 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

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Background: Escherichia coli is one of the causatives of infection agents. Noni fruit that contains the antibacterial ingredients was predicted as an alternative medicine to reduce the resistance of antibiotics. Noni fruit extract can inhibit the growth of Escherichia coli. The absence of research on the active substances contained in this fruit which plays a role in inhibiting the growth of Escherichia coli encourages the researcher to conduct this research.Methodology: The research was an experimental laboratory with post-test only control group design. The Escherichia coli grown on Mac conkey agar. Flavonoid and tannin in noni fruit (Morinda citrifolia Linn.) diluted with 3 concentrations, 50%, 70%, 100% and 2 control groups, positive control with ceftriaxone and negative control with Dimethylsulfoxide 10% (DMSO). The treatment group were incubated for 24 hours, then the inhibitory zone formed was measured in mm. Results: The Kruskall-Wallis test showed significant difference in all concentration. The results obtained from this research showed that the average of inhibition towards Escherichia coli on positive control (22.83 mm) had the largest inhibition zone among flavonoid 100% (18.83mm), flavonoid 70% (14.67 mm), flavonoid 50% (6 mm), tannin 100% (17.33 mm), tannin 70% (10.83 mm), tannin 50% (7.50 mm), and negative control (2 mm).Conclusion:  Flavonoid and tannin in noni fruit (Morinda citrifolia Linn) were effective for inhibiting the growth of Escherichia coli. The 100% concentration is the most effective concentration that can be promoted as an alternative medicine.
The Influence Of Compliance With Prolanis Participants On Blood Sugar Levels In Type 2 DM Patients In 3 Health Centers In Cirebon City Bambang Wibisono; Mavisiurohmah, Mavisiurohmah; Atik Sutisna
Jurnal EduHealth Vol. 14 No. 04 (2023): Jurnal eduHealt, 2023, December
Publisher : Sean Institute

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Type 2 DM was a chronic disease that caused major morbidity and mortality, like other chronic diseases. Various management efforts undertaken by patients with type 2 DM none other but aimed at controlling the blood glucose levels in patients. The government launched a program from the Health Social Security Organizing Agency (BPJS) named the Chronic Disease Management Program (PROLANIS). Purpose : This study aims to determine the effect of PROLANIS compliance participants on blood sugar levels in patients with type 2 DM. Method : This research was an observational study with a cross-sectional design using the Simple Random Sampling technique. The number of samples obtained is 50 samples. Primary data were obtained from a questionnaire filled out by PROLANIS participants with type 2 diabetes. Result : The results of the analysis used the spearmen correlation test that there was no effect between education compliance to increase knowledge (p = 0.316), PROLANIS exercises (p = 0.633), and taking medication (p = 0.633) on blood sugar levels of type 2 DM patients. The relationship (p = 0.038) between adherence to carry out medical nutritional therapy to the levels of GDS of type 2 DM patients. Conclusions : There was no effect between education compliance to increase knowledge, PROLANIS exercises, and taking medication of PROLANIS participants on blood sugar levels of patients with type 2 diabetes. The effect between adherence to carry out medical nutritional therapy to the levels of GDS of type 2 DM patients.
Co-Authors Bambang Wibisono Hikmah Fitriani Mavisiurohmah, Mavisiurohmah Tessa Swesty Islamia