Putri, Arridha Hutami
Fakultas Kedokteran, Universitas Muhammadiyah Sumatera Utara

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Journal : Buletin Farmatera

Role of Breastfeeding and Onset of Atopic Dermatitis in Children Patient: a Cross Sectional Study Arridha Hutami Putri; Sri Wahyuni Purnama; Irma Damayanti Roesyanto
Buletin Farmatera Vol 5, No 2 (2020)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (439.527 KB) | DOI: 10.30596/bf.v5i2.3769

Abstract

Abstract: Atopic dermatitis (AD) is a multifactorial disease belongs to the "burden disease" in childhood. It needs to be prevented to reach their optimal growth. Exclusive breastfeeding given during the first six months of life provides nutritional benefits and is thought to protect children from allergic or infectious diseases, such as AD. This study aims to determine the relationship between breastfeeding and onset of atopic dermatitis. This was an observational analytic study using cross-sectional method. Samples were taken consecutively at the Dermatovenereology Polyclinic of referral hospital and Puskesmas in Medan. This study included all pediatric patients aged 6 months to <18 years diagnosed with AD and were interviewed with informed consent. Children who didn’t get breastmilk were excluded. There result was a significant relationship between breastfeeding (exclusively to partially) and AD onset. There was no relationship between breastfeeding (exclusively to prelacteally) and AD onset. Polyunsaturated fatty acids, sIgA, and TGF-β2 in the breast milk of mothers with atopy is lower than mothers without atopy. Breastfeeding exclusively has a protective effect on AD. Further research is needed to analyzes various factors by comparing genetic predisposition.
Bandage Effect Antiaging Cream Channa Striata Extract (Snakehead Fish) With Tretinoin Cream 0.1% Against Photoaging Indrawan, Yudi; Putri, Arridha Hutami
Buletin Farmatera Vol 10, No 3 (2025)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v10i3.24635

Abstract

Abstract: Photoaging is a skin aging process that occurs due to sun exposure causing damage to the skin. From the results of the study, it was also found that the most visible signs of premature aging were not fine lines or wrinkles, but dull skin with a percentage of 53.30%. Snakehead fish has a protein level in 100 grams of fish meat reaching 25.2 grams. The albumin level of snakehead fish is quite high up to 6.22%, and the zinc mineral content from snakehead fish reaches 1.74 mg/100 grams, with high levels of protein and albumin snakehead fish useful as photoaging therapy. This study aims to find out whether there is a difference in effect between the use of Channa striata (snakehead fish) extract cream and 0.1% tretinoin cream as photoaging therapy. This type of study is a randomized control trial using 2 groups, namely the group with the administration of snakehead fish cream test material and the group with the 0.1% tretinoin cream test material for 30 days with a total sample of 96 people, each sample will be observed at the beginning and end of the treatment using the Glombau scale. Based on the results of the study, there was no difference in effectiveness between the use of Channa Striata (snakehead fish) extract cream and 0.1% tretinoin cream on photoaging (p=1.00). There was no comparison of effectiveness between the use of Channa Striata (snakehead fish) extract cream and 0.1% tretinoin cream on photoaging.