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All Journal Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya International Journal of Community Service
Suryadi Tjekyan
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Religion Humanities Biochemistry, Genetics & Molecular Biology Education Environmental Science Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Medicine & Pharmacology Neuroscience Public Health Social Sciences Other

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Efektivitas Pemberian Ekstrak Daun Binahong (Anredera Cordifolia) Terhadap Ketebalan Jaringan Granulasi dan Jarak Tepi Luka pada Penyembuhan Luka Sayat Tikus Putih (Rattus Norvegicus) Pariyana Pariyana; Mgs. Irsan Saleh; Suryadi Tjekyan; Hermansyah Hermansyah
JURNAL KEDOKTERAN DAN KESEHATAN Vol 3, No 3 (2016)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Luka merupakan kondisi hilangnya kontinuitas struktur jaringan. Salah satu tanaman obat yang ikut berperan dalam membantu proses penyembuhan luka adalah tanaman binahong (Anredera cordifolia). Tujuan penelitian ini untuk mengetahui efektifitas pemberian ekstrak daun binahong terhadap ketebalan jaringan granulasi dan jarak tepi luka pada penyembuhan luka sayat tikus putih (Rattus norvegicus).Studi eksperimental yang menggunakan rancangan penelitian post test only control group designdilaksanakan bulan Februari-April 2014 di Laboratorium Teknik Kimia Universitas Sriwijaya, Animal House Fakultas Kedokteran Unsri dan Laboratorium Patologi RSUP dr.Mohammad Hoesin Palembang. Sampel yang digunakan adalah tikus putih sebanyak 30 sampel dibagi menjadi 5 kelompok perlakuan yaitu kontrol negatif diberikan vaselin, ekstrak daun binahong 10%, 20%, 40% dan kontrol positif diberikan salep madecassol). Data dianalisis menggunakan program SPSS versi 19 dengan uji homogenitas, independent t-test, uji OneWay Anova dilanjutkan uji post hoc multiple comparisons. Hasil penelitian didapatkan pada pemberian ekstrak daun binahong dosis 10% (p=0.001) dan 20% (p=0.002) dibandingkan dengan salep Madecassol menunjukkan ada perbedaan bermakna rerata ketebalan jaringan granulasi dan jarak tepi luka sedangkan ekstrak daun binahong 40% dibandingkan dengan salep Madecassol pada luka sayat tikus putih menunjukkan tidak ada perbedaan bermakna rerata ketebalan jaringan granulasi dan jarak tepi luka (p=0.563). Kesimpulan penelitian ekstrak daun binahong mempunyai efek yang sama dengan salep Madecassol terhadap ketebalan jaringan granulasi dan jarak tepi luka pada luka sayat tikus putih. Dosis yang paling efektif terdapat pada ekstrak daun binahong 40%.Diperlukan penelitian lanjutan untuk membuktikan efek ekstrak daun binahong (anredera cordifolia) terhadap enzim-enzim pada saat proses inflamasi (seperti TGF, PDGF, KGF, VEGF) serta toksisitas dari daun binahong.
An Overview of Knowledge of Traditional Medicine for Self-medication in the Community in the Era of the COVID-19 Pandemic Pariyana; Muhammad Aziz; Mariana; Suryadi Tjekyan; Puji Rizki Suryani; Theodora Viani; Salsa Amalia
International Journal Of Community Service Vol. 1 No. 2 (2021): August 2021 (Indonesia - Malaysia)
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijcs.v1i2.19

Abstract

Self-medication is usually used by the community to treat minor illnesses, especially during the COVID-19 pandemic, such as fever, dizziness, cough, flu, pain, ulcers, diarrhea, and others. Most self-medication leads to inappropriate drug use. Self-medicated knowledge is the key to prevent unwanted events, one of the example is by providing education about traditional medicine for self-medication. In addition, making a plantation pharmacy is also a solution to make it easier for people to obtain traditional medicines. The method of implementing this community service activity is to provide counseling on using traditional medicine for self-medication and planting pharmacy plantation. An overview of knowledge of traditional medicine for self-medication in the community in the era of the COVID-19 pandemic is descriptive research by looking at primary data (from questionnaires) taken in a cross-sectional manner. Based on the data obtained, it can be concluded that most people have a sufficient level of knowledge (59.09%). The community has a positive attitude towards traditional medicine self-medication as evidenced by the number of respondents who answered agree from these statements. Therefore, research can be carried out as well as counseling, education and health promotion to society with a larger sample.
Co-Authors Hermansyah Hermansyah Mariana Mgs. Irsan Saleh Muhammad Aziz Pariyana Pariyana Pariyana Puji Rizki Suryani Salsa Amalia Theodora Viani