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Journal : Jurnal MedScientiae

Ginger Rhizome Extract (Zingiber officinale) as an Alternative Bioinsecticide Against The Mortality of German Cockroach (Blattella germanica): Indonesia Susanto, Inneke Kusumawati; Susilowati, Rina Priastini; Hidajat, Joshua Jean Michael
Jurnal MedScientiae Vol. 3 No. 1 (2024): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i1.3053

Abstract

Cockroach is one of the types of insects that exists everywhere. Cockroach can live in a lot of places, such as the gutter, the trash, and even in the bathroom. Cockroach is one of the agents that is responsible for the spreading of diseases such as diarrhea, dysentery and cholera in children. In Indonesia, there exists a lot of different types of cockroach, one of it is the German Cockroach or Blattella germanica L., and the cockroach problem in Indonesia is mainly handled by using chemicals insecticides, this happens because there’s a lot and its commonly found in a lot of places. Pyrethroid based chemicals insecticides are one of the most common chemical insecticides used by the public. These chemical insecticides have various kinds of adverse effects because they leave residues that can be inhaled by humans and also consumed by humans through food products. Some of the effects of chemical insecticides are diseases of the liver, kidneys, and also problems with the central nervous system. Therefore, an alternative solution is needed in dealing with the cockroach problems in Indonesia, namely Bioinsecticides. Bioinsecticides are insecticides made using natural ingredients without the addition of chemical substances. Ginger is one of the spices that can be found anywhere, in ginger there are compounds called flavonoids, and these compounds can be used as bioinsecticides. Bioinsecticides are made by taking the ginger extract then putting the extract into a spray bottle according to the dose using a pasteur pipette.  
Pharmacotherapy Study Of Albendazole And Mebendazole For Soil Transmitted Helminths Infections In Children Susanto, Inneke Kusumawati; William, William; Agatha, Nabila
Jurnal MedScientiae Vol. 3 No. 2 (2024): Agustus
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i2.3109

Abstract

Soil Transmitted Helminths (STH) infection is a nematode infection of the intestine that requires soil for its transmission. The worms that cause Soil Transmitted Helminths infection include; Ascaris lumbricoides, Trichuris trichiura, hookworms (Necator americanus and Ancylostoma duodenale. The incidence of STH infection is quite high with the highest spread of STH infection in the child age group. Treatment of cases of STH infection is by administering antihelmintic drugs or worming drugs. Although there are four The drugs recommended by WHO, only the two drugs most often used in the treatment of STH infections, namely albendazole and mebendazole. Both drugs have been used for more than 30 years, but cases of STH infection still have a high incidence. That is why this literature review was written aims to describe the efficacy of the two drugs for STH infection in children so that their effectiveness can be assessed.The research method used was a literature review, a literature search was sourced from Proquest, Google scholar, Pubmed, Elsevier and Europe PMC. keywords Albendazole, Mebendazole, Soil Transmitted Helminths Infections, Children. There are 10 selected literatures to be studied in this literature review. The results showed that albendazole had satisfactory efficacy in STH infections caused by Ascaris lumbricoides and hookworms, but reduced efficacy in Trichuris trichiura worms. Mebendazole has satisfactory efficacy in STH infections caused by Ascaris lumbricoides and Trichuris trichiura, but reduced efficacy in hookworms. Albendazole and mebendazole does not cause side effects.
Uji Efektivitas Ekstrak Kulit Manggis terhadap Pertumbuhan Jamur Malassezia furfur Susanto, Inneke Kusumawati; Pasaribu, Donna Mesina Rosadini; Laurensia Charlina Nova Sambut
Jurnal MedScientiae Vol. 4 No. 3 (2025): Desember
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v4i3.3607

Abstract

Background Mangosteen is one of the medicinal plants that has long been known in Southeast Asia, with its skin having various of properties, including antibacterial, antifungal, anti-inflammatory, and antioxidant. Mangosteen skin in traditional medicine is used to cure various diseases. One of the fungi that can cause skin disease in human is Malassezia furfur, which is a lipophilic fungus and part of the normal skin microflora. Objective: This study aims to determine and prove whether mangosteen skin extract has antifungal activity against Malassezia furfur. Method: This study used an experimental method to test the antifungal activity of mangosteen skin extract. Testing was carried out using the Minimum Inhibitory Concentration (MIC), Minimum Bactericidal Concentration (MBC), and diffusion methods to measure the inhibitory power against Malassezia furfur at various extract concentrations. Results: The results showed that mangosteen skin extract has antifungal activity against Malassezia furfur. The extract concentration that gave the greatest inhibitory power was 100%, while the lowest concentration that showed inhibitory power was 20%. Conclusion: Mangosteen peel extract has been proven to have antifungal activity against Malassezia furfur, with a concentration of 100% providing the greatest inhibitory effect, while a concentration of 20% still shows an inhibitory effect, but weaker.