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Antibiotic Susceptibility Profile in Urinary Tract Infection Patients at Tarakan Regional Hospital Dharmawan, Ade; Wijaya, Pande I Gede Indra; Septiana, Yorisye; Pasaribu, Donna Mesina Rosadini; Tan, Henny Tannady; Simanjuntak, Lasma Susi F.
Muhammadiyah Medical Journal Vol 5, No 1 (2024): Muhammadiyah Medical Journal (MMJ)
Publisher : Faculty of Medicine and Health Universitas Muhammadiyah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24853/mmj.5.1.28-35

Abstract

Background: Urinary tract infections (UTIs) are common in the community and hospital. In Indonesia, the incidence of UTI reaches 180,000 new cases per year. The most common pathogenic bacteria causing UTIs are dominated by Escherichia coli. Early empirical treatment of UTI cases can reduce morbidity. Knowing the pathogenic bacteria involved in urinary tract infections and their antimicrobial susceptibility patterns is necessary to provide appropriate empirical therapy. Purposes: Describe bacterial patterns and susceptibility profiles in urinary tract infection patients. Methods: A retrospective UTI dataset between 2019-2021whom admitted to Tarakan Regional General Hospital with a diagnosis of UTI. Resistance marker data for ESBL were obtained from the results of identification and resistance using the BD PhoenixTM Automated Microbiology System (Becton Dickinson, USA). The data was analyzed descriptively. Results: As many as 40 isolates were analyzed. Consist of E.coli (37.5%), Enterococcus faecium (20%) and Klebsiella pneumoniae (17.5%). The ESBL-producing E.coli bacteria rate reached 60%, while ESBL-producing K. pneumoniae reached 100%. Conclusion: E. coli was the most common pathogen, with the highest antibiotic sensitivity being imipenem, meropenem, and amikacin.
Isolasi Bakteri Methicillin Resistant Staphylococcus aureus pada Gagang Pintu Gedung Kampus X di Jakarta Pasaribu, Donna Mesina Rosadini; Kelvin, Kelvin; Timotius, Kris Herawan
Jurnal MedScientiae Vol. 3 No. 1 (2024): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i1.3062

Abstract

Bacteria are one of the component parts in every ecosystem. Staphylococcus aureus (S. aureus) is a normal surface flora of the human body, as a temporary contaminant on inanimate objects such as clothing, cutlery and doorknobs, but also a oportunistic even pathogen on the host. The mutated strain of S. aureus has a cross-resistant strain against all antibiotics of the Beta Lactam, Methicillin, Oxacillin and Flucloxacillin groups, called Methicillin Resistant Staphylococcus aureus (MRSA). This research is needed because MRSA is a strain of bacteria that can be everywhere, especially in public facilities, such as doorknobs, which can be a place of transmission (transfer) of bacteria from one host to another. The samples in this study were taken by swabbing from the door handle in building X, Jakarta. A total of 62 samples were then cultured on Mannitol Salt Agar (MSA) media, the growing isolate was tested by Gram staining, catalase test, and mannitol. Isolate suspected of Staphylococcus aureus, ascertained whether MRSA strain using 30 μg antibiotic C efoxitin (fox) disc. The results of this study showed that 58 (87%) isolates were Staphylococcus aureus and sensitive to C efoxitin antibiotics, 8 (13%) isolates, mnitol test negative, sensitive to Ceroxitin antibiotics. The study concluded that the bacterial isolate found was Staphylococcus aureus sensitive methicillin (MSSA), no MRSA was found.
TELAAH PUSTAKA: PERAN AG-PTFE (PELAPIS KATETER URINE) UNTUK MENCEGAH CATHETER ASSOCIATED URINARY TRACT INFECTION (CAUTI) Haq, Satria Addienul; Gunardi, Wani Devita; Pasaribu, Donna Mesina Rosadini; Sumbayak, Erma Mexcorry
Medika Kartika : Jurnal Kedokteran dan Kesehatan Vol 6 No 4 (2023): Medika Kartika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran Universitas Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Biofilm pada kateter merupakan salah satu penyebab terjadinya Catheter Associated Urinary Tract Infection (CAUTI). Telaah pustaka ini bertujuan mengetahui manfaat dan efektivitas pelapisan antibiofilm pada kateter urine dalam mencegah CAUTI. Pustaka yang dihimpun dalam telaah ini diperoleh melalui database electronic seperti Proquest dan PubMed menggunakan beberapa kata kunci yaitu, antibiofilm, biofilm, catheter, dan CAUTI. Semua jurnal yang diperoleh diseleksi menggunakan kriteria yang telah ditentukan, seperti artikel penelitian eksperimental, tahun publikasi kurang dari 10 tahun, dan penelitian menggunakan lapisan antibakteri pada permukaan kateter. Delapan jurnal hasil seleksi digunakan sebagai acuan utama pada telaah pustaka ini. Efektivitas yang baik dalam mencegah terbentuknya biofilm ditunjukkan oleh beberapa antibiofilm berikut, yakni, Amino Selulosa-nanosphere (ACNS), Chlorhexidine-nanosphere (CHX-NS), Ag/Poli-p-xylylenen hydrophilic (Ag/PPX-N), Perak-polytetrafluoroethylene (AG- PTFE), Perak-nanopartikel (Ag-NPs), Sodium selenite, dan Octenidine Dihydrochloride (OH). Bakteriuria dapat dihambat dalam waktu lama (> 30 hari) oleh antibiofilm Perak-polytetrafluoroethylene (AG- PTFE). Hal tersebut menunjukkan bahwa pelapisan kateter menggunakan antibiofilm memiliki potensi dalam mencegah terjadinya bakteriuria dan terbentuknya biofilm penyebab CAUTI. Kata Kunci: antibiofilm, CAUTI, kateter DOI : 10.35990/mk.v6n4.p395-405
Identifikasi Keberadaan Soil Transmitted Helminths pada Sayuran Lalapan di Warung Makan Grogol Petamburan Susanto, Inneke Kusumawati; Pasaribu, Donna Mesina Rosadini; Suhandi, Priska Yoverani
Jurnal Kedokteran Meditek Vol 31 No 4 (2025): JULI
Publisher : Fakultas Kedokteran Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jkdoktmeditek.v31i4.3394

Abstract

Introduction: Soil Transmitted Helminths (STH) infection is a worm infection through the soil. Consumption of raw food such as fresh vegetables is a route of STH transmission to humans because soil is a growth medium for vegetables and an ideal place for worm development into an infective form so that there is a risk of contamination when the soil is contaminated with human feces containing worm eggs. Transmission through the use of vegetable fertilizers contaminated with human feces, vegetables that are not washed properly and poor food management. Research on STH eggs in fresh vegetables in Grogol Petamburan food stalls has never been conducted. Objective: The study aims to determine the presence or absence of STH, the prevalence of contamination, stages and types of STH eggs in fresh vegetables in Grogol Petamburan food stalls to provide the public with information to pay attention to the cleanliness of fresh vegetables. Method: The study was descriptive with microscopic examination using the sedimentation method. The sampling technique was a total sampling of 84 fresh vegetables samples taken from 38 Grogol Petamburan food stalls. Fresh vegetables samples, namely cabbage, lettuce and basil, were examined in the parasitology laboratory. Data on hygiene and sanitation practices were taken from interviews. Results: STH identification results in 9 samples (10.7%) were positive for STH contamination. Ascaris lumbricoides eggs were found in the contaminated samples, while Trichuris trichiura and Hookworm were not found. Conclusion: Based on the results of the study, the samples were positive for STH contamination in the Ascaris lumbricoides egg stage. The results indicate that the raw vegetables are not suitable for consumption.