Misran Lawani
Department of Agricultural Product Technology, Faculty of Agriculture, Khairun University, Jl. Raya Kampus Unkhair Gambesi Ternate, Ternate 97719, North Maluku, Indonesia

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Chemical Investigation and Antimicrobial Activity of Medicinal Plant Toddalia asiatica Lam Wilmar Maarisit; Misran Lawani
Indonesian Journal of Chemistry Vol 20, No 5 (2020)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (271.706 KB) | DOI: 10.22146/ijc.46643

Abstract

Medicinal plants have become important sources of natural products, which have been used in the development of therapeutic agents. Four new coumarins (1-4) have been isolated together with five known metabolites (5-9) from the medicinal plant T. asiatica. The structures of 1-9 were assigned based on their spectroscopic data. Compounds (1-9) inhibited the growth of the Gram-negative bacteria E. coli and Gram-positive bacteria S. aureus at a concentration of 25 and 50 μg/disc. Compounds (2-4) inhibited the phytopathogenic fungus C. cucurbitarum at 50 μg/disc.