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Pengaruh Polaritas Pelarut terhadap Efisiensi Ekstraksi Total Alkaloid dari Daun Rambai (Sonneratia caseolaris) Siti Masodah; Niken widiastuti hariati; Nurmeily Rachmawati; Serli Dwi Nurhayati
Jurnal Skala Kesehatan Vol. 17 No. 1 (2026): Jurnal Skala Kesehatan Edisi Januari 2026
Publisher : Politeknik Kementerian Kesehatan Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31964/jsk.v17i1.494

Abstract

Diabetes mellitus is a non-communicable disease with a rising prevalence. Alkaloids are known to have antidiabetic effects by inhibiting carbohydrate-digesting enzymes and enhancing glucose metabolism. This study aimed to determine the total alkaloid content of Rambai leaves (Sonneratia caseolaris) using solvents with different polarities: ethanol and n-hexane. A descriptive study was conducted using the maceration method, followed by quantification of alkaloids with the quinine equivalent method using a UV-Vis spectrophotometer. Results showed that ethanol extract produced a higher yield (17.72 g; 35.44%) compared to n-hexane (3.09 g; 6.18%). The alkaloid content in the ethanol extract was 414.43 µg/g, nearly twice that of n-hexane (217.09 µg/g). Statistical analysis revealed a significant difference (p<0.001). Ethanol was proven to be more effective in extracting polar to semi-polar alkaloid compounds. The high alkaloid content indicates Rambai leaves have potential as a natural source for diabetes therapy. These findings provide a foundation for future product development and preclinical trials.
Pembinaan dan Pedampingan Kader Santri Sehat Dalam Mewujudkan Pola Hidup Bersih dan Sehat (PHBS) di Ponpes Al-Mubarok Nurmeily Rachmawati; Venny Patricia; Syarah Anliza
Jurnal Pengabdian Masyarakat - PIMAS Vol. 5 No. 3 (2026): Agustus
Publisher : LPPM Universitas Harapan Bangsa Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35960/pimas.v5i3.2518

Abstract

One of the government's health development programs, outlined in the National Medium-Term Development Plan (RPJMN), relates to the national development strategy and programs of each ministry over a specific timeframe, namely towards a Indonesia Sehat, namely Clean and Healthy Living Behavior (PHBS). However, this program continues to be implemented because not all provinces have significantly improved PHBS. One indicator of the PHBS program is preventing the spread of infectious diseases through handwashing with antiseptic and using clean water. The goal of this community service activity to address partner issues is to increase the students' knowledge of PHBS, particularly regarding handwashing with soap, proper handwashing, and soap-making skills. The results showed that the knowledge of students increase by results of pre and posttest. The number of germs before and after washing hands were decreased. The students implemented PHBS very well by making soap from kit soap that been given.