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All Journal Narra J
Lee Smith
Centre for Health Performance and Wellbeing, Anglia Ruskin University, Cambridge, UK
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Acute severe hepatitis of unknown etiology in children: A mini-review Andri Frediansyah; Malik Sallam; Amanda Yufika; Khan Sharun; Muhammad Iqhrammullah; Deepak Chandran; Sukamto S. Mamada; Dina E. Sallam; Yousef Khader; Yohannes K. Lemu; Fauzi Yusuf; James-Paul Kretchy; Ziad Abdeen; J. Smith Torres-Roman; Yogesh Acharya; Anastasia Bondarenko; Aamer Ikram; Kurnia F. Jamil; Katarzyna Kotfis; Ai Koyanagi; Lee Smith; Dewi Megawati; Marius Rademaker; Talha B. Emran; Ziad A. Memish; Sandro Vento; Firzan Nainu; Harapan Harapan
Narra J Vol. 2 No. 2 (2022): August 2022
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v2i2.83

Abstract

The emergence of acute, severe non hepA–E hepatitis of unknown etiology (ASHUE) has attracted global concern owing to the very young age of the patients and its unknown etiology. Although this condition has been linked to several possible causes, including viral infection, drugs and/or toxin exposure, the exact cause remains unknown; this makes treatment recommendation very difficult. In this review, we summarize recent updates on the clinical manifestations, complemented with laboratory results, case numbers with the global distribution and other epidemiological characteristics, and the possible etiologies. We also provide the proposed actions that could be undertaken to control and prevent further spread of this hepatitis. Since many etiological and pathological aspects of the acute non hepA–E hepatitis remain unclear, further research is needed to minimize the severe impact of this disease.
Co-Authors Aamer Ikram Ai Koyanagi Amanda Yufika Anastasia Bondarenko Andri Frediansyah Deepak Chandran Dewi Megawati Dina E. Sallam Fauzi Yusuf Firzan Nainu Harapan Harapan Iqhrammullah, Muhammad J. Smith Torres-Roman James-Paul Kretchy Katarzyna Kotfis Khan Sharun Kurnia F. Jamil Malik Sallam Marius Rademaker Sandro Vento Sukamto S. Mamada Talha B. Emran Yogesh Acharya Yohannes K. Lemu Yousef Khader Ziad A. Memish Ziad Abdeen