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All Journal Jurnal Yoga Dan Kesehatan Jurnal Sains dan Kesehatan
Wisnu Cahyo Prabowo
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Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology

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Formulasi Infusan Daun Sirih Merah (Piper crocatum) sebagai Gel Antiseptik Tangan Wisnu Cahyo Prabowo; Wahyu Widayat; Synthia Defriana
Jurnal Sains dan Kesehatan Vol. 1 No. 10 (2018): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v1i10.59

Abstract

Melimpahnya sumberdaya alam Indonesia khususnya dalam pemanfaatannya sebagai bahan obat maupun kosmetik. formulasi sediaan obat tidak hanya mengandalkan bentuk fisik sediaan yang baik tetapi juga efektivitas/khasiat yang baik. Sasaran penelitian ini bertujuan untuk memperoleh sediaan gel antiseptik dengan bahan aktif daun sirih merah yang efektif membunuh mikroba ditangan serta daya hambat terhadap beberapa mikroba uji yang patogen. Bahan segar diekstraksi kemudian diformulasi dengan basis gel. Sediaan gel dengan berbagai konsentrasi diuji stabilitas berdasarkan penyimpanannya. Efektifitas sediaan tersebut di uji terhadap mikroba tangan dan beberapa mikroba patogen. Potensi efektifitas sediaan diperoleh dengan membandingkan dengan sediaan kontrol berbahan aktif etanol dan triklosan. Sediaan gel antiseptik ekstrak daun sirih merah baik stabil pada penyimpanan suhu 18-27oC dengan pH 5,5 dan memiliki warna bening kekuningan. Konsentrasi sediaan gel antiseptik efektif pada 25% terhadap mikroba tangan yang setara dengan handsanitizer alkohol, sedangkan pada konsentrasi efektif 15% terhadap Candida albican; konsentrasi 20% terhadap Candida utilis; dan 25% terhadap Vibrio cholera, keseluruhannya setara dengan handsanitizer alkohol.
Akupunktur Garuda Indonesia dan Perubahan Kadar Asam Urat pada Pasien Gout Artritis Agustina, Risna; Wisnu Cahyo Prabowo
Jurnal Yoga dan Kesehatan Vol 9 No 2 (2026): Jurnal Yoga dan Kesehatan
Publisher : UHN IGB Sugriwa Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25078/jyk.v9i2.7401

Abstract

Gout requires sustained urate control, whereas evidence on acupuncture-related changes in urate biomarkers remains inconsistent. This study examined pre-post changes in blood uric acid across three sessions of Garuda Indonesia (GI) Acupuncture using a single-group repeated-measures design. Complete data were available for 24 participants aged 20–58 years (mean 35.2±10.3 years), comprising 15 females (62.5%) and 9 males (37.5%). The three sessions were separated by 6-day intervals, and uric acid was measured 30 minutes before and 10 minutes after each session using an EasyTouch® GCU ET-301 with capillary whole blood. Analyses included descriptive statistics, a linear mixed-effects model, paired t-tests with Holm adjustment, Wilcoxon sensitivity analyses, and Cohen’s dz. Mean values changed from 6.16±1.78 to 5.85±1.63 mg/dL in Session 1, 6.19±1.50 to 5.86±1.33 mg/dL in Session 2, and 6.00±1.60 to 5.73±1.44 mg/dL in Session 3. The corresponding mean reductions were 0.304 mg/dL (95% CI 0.116–0.492), 0.325 mg/dL (95% CI 0.150–0.500), and 0.271 mg/dL (95% CI 0.098–0.444). The mixed model estimated an overall reduction of 0.300 mg/dL (95% CI 0.204–0.396; p<0.001), with no evidence that the pre-post effect differed across sessions (interaction p=0.901). In each session, 19 of 24 participants showed a decrease. The pattern was statistically consistent, but the absolute change was small and reflects only a very short-term change assessed 10 minutes after each session. Because the study had no control group, recruitment procedures were incompletely documented, hydration was not standardized, comorbidities were not collected systematically, and renal function was not assessed, the findings remain exploratory and do not establish causality or long-term gout control.
Co-Authors Agustina, Risna Synthia Defriana Wahyu Widayat