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Indah Purnamasari
Universitas Sari Mulia
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Analisis Rhodamin B Dalam Lipstick Di Kecamatan Banjarmasin Utara Hansel Hens Tangkas; Trias S. Putri; Syarifah S. Aisyah; Hairunnisa Hairunnisa; Helda Oktavia; Indah Purnamasari; Siti Salbiah; Rahmadani Rahmadani
Jurnal Pelayanan Kefarmasian dan Sains Vol 2 No 2 (2022): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (822.101 KB) | DOI: 10.33859/jpcs.v2i2.190

Abstract

Background: Rhodamine B is a synthetic substance which is generally used as a dye in paper, textile or ink which causes respiratory irritation and when used can cause cancer and liver damage in the body. The use of Rhodamine B for a long time will cause acute danger if swallowed and cause vomiting which causes irritation of the digestive tract and causes symptoms of poisoning. The purpose of this study was to determine the presence of lipstick containing Rhodamine B. The testing method carried out used for qualitative testing is Thin Layer Chromatography (TLC) and quantitative testing using UV-VIS Spectrophotometry. The results of the lipstick sample were qualitatively proven to contain rhodamine B with a mobile phase and a stationary phase of 70% ethanol: ammonia: ethyl acetate (5:2,5:12,5) and silica gel 254 nm. With an RF value of 0.57. In quantitative testing, rhodamine B levels were found to be 2.598 mg/L. Conclusion lipsticks circulating in the East Banjarmasin sub-district are proven to contain rhodamine B.
Analisis Rhodamin B Dalam Lipstick Di Kecamatan Banjarmasin Utara Hansel Hens Tangkas; Trias S. Putri; Syarifah S. Aisyah; Hairunnisa Hairunnisa; Helda Oktavia; Indah Purnamasari; Siti Salbiah; Rahmadani Rahmadani
Jurnal Pelayanan Kefarmasian dan Sains Vol 2 No 2 (2022): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v2i2.190

Abstract

Background: Rhodamine B is a synthetic substance which is generally used as a dye in paper, textile or ink which causes respiratory irritation and when used can cause cancer and liver damage in the body. The use of Rhodamine B for a long time will cause acute danger if swallowed and cause vomiting which causes irritation of the digestive tract and causes symptoms of poisoning. The purpose of this study was to determine the presence of lipstick containing Rhodamine B. The testing method carried out used for qualitative testing is Thin Layer Chromatography (TLC) and quantitative testing using UV-VIS Spectrophotometry. The results of the lipstick sample were qualitatively proven to contain rhodamine B with a mobile phase and a stationary phase of 70% ethanol: ammonia: ethyl acetate (5:2,5:12,5) and silica gel 254 nm. With an RF value of 0.57. In quantitative testing, rhodamine B levels were found to be 2.598 mg/L. Conclusion lipsticks circulating in the East Banjarmasin sub-district are proven to contain rhodamine B.
Uji Aktivitas Antioksidan Ekstrak Daun Pepaya Jepang (Cnidoscolus acanitifolius) dengan Metode Frap: Antioxidant Activity Test Of Japanese Papaya Leaf Extract (Cnidoscolus aconitifolius) Using FRAP Method Indah Purnamasari; Rohama Rohama; Noval Noval
Jurnal Surya Medika (JSM) Vol. 10 No. 1 (2024): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v10i1.7205

Abstract

Indonesia merupakan negara yang memiliki tumbuhan yang banyak dimanfaatkan sebagai obat. Salah satunya adalah daun papaya jepang (Cnidoscolus aconitifolius) yang terbukti mengandung antioksidan dan secara empiris dapat mengobati demam berdarah dan hipertensi. Penelitian ini membandingkan aktivitas antioksidan dari sampel daun pepaya jepang yang diekstrak dengan pelarut yang berbeda. tujuan dari penelitian yaitu untuk Mengetahui pengaruh jenis kepolaran pelarut ekstraksi dalam aktivitas antioksidan ekstrak dari daun papaya jepang dengan metode FRAP. Pada penelitian ini simplisia daun pepaya jepang diekstraksi dengan cara maserasi. Skrining fitokimia dan uji aktivitas antioksidan dilakukan pada kedua ekstrak. Pengujian aktivitas antioksidan dilakukan dengan menggunakan metode FRAP (Ferric Reducing Antioxidant Power). Aktivitas antioksidan diuji secara kuantitatif dengan menggunakan spektrofotometri Uv-Vis pada panjang gelombang 695 nm dengan baku pembanding yang digunakan adalah asam askorbat. Hasil analisis kualitatif menunjukan ekstrak etanol 96% positif mengandung flavonoid, tanin, saponin, alkaloid, fenolik, steroid. sedangkan pada ekstrak etil asetat negatif saponin. Kekuatan antioksidan dari nilai FRAP dapat dinyatakan dalam mg ascorbic acid equivalent / gram sampel (mgAAE/g sampel). Sehingga didapat nilai mgAAE/g ekstrak etanol daun pepaya jepang sebesar 81,49 mgAAE/g, dan ekstrak etil asetat sebesar 131,33 mgAAE/g. Dapat disimpulkan bahwa ekstrak daun papaya jepang menggunakan pelarut etanol 96% mengasilkan aktivitas antioksidan yang lebih kuat dibandingankan dengan pelarut etil asetata serta menunjukkan perbedaan yang signifikan antara dua pelarut yang digunakan pada uji independent sampel t test.
Co-Authors Hairunnisa Hairunnisa Hansel Hens Tangkas Hansel Hens Tangkas Helda Oktavia Noval Noval Rahmadani Rahmadani Rohama Rohama Siti Salbiah Syarifah S. Aisyah Trias S. Putri