Maria Caecilia N.Setiawati
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STATINS DRUG USE AND DRUG-DRUG INTERACTIONS Maria Caecilia N.Setiawati; Caecilia Mutiarawati; Uswatun Chasanah; Lina Fatin Fauziyyah
Jurnal Ilmu Farmasi dan Farmasi Klinik Vol 17, No 2 (2020): Jurnal Ilmu Farmasi & Farmasi Klinik Vol. 17 N0. 02 Desember 2020
Publisher : Universitas Wahid Hasyim Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (619.426 KB) | DOI: 10.31942/jiffk.v17i2.4068

Abstract

ABSTRACT Dyslipidemia is the commonest cause of many atherosclerotic diseases. Statins are the mainstay of the management of dyslipidemia, and it is widely prescribed for patients in Indonesia. This study aims to give an overview, the use of statin, and its drug-drug interactions. The study method was descriptive, using a purposive sampling technic. The inclusion criteria were patients who received statins therapy, in the outpatient installation of Tugurejo Regional Public Hospital, Semarang, during April 2017. There were 334 patients meet the inclusion criteria, most of them were women (63,28%). The highest patients’ range was 60-69 years old of 129 patients (38,62%). One hundred and thirty-one patients (39,22%) were diagnosed with dyslipidemia only. The dosage range of simvastatin and rosuvastatin was 10 to 20 mg once daily, but rosuvastatin was only given 10 mg once daily. The most dose was 10 mg simvastatin per day, prescribed for 231 patients (69,16%). There were 177 patients (52,99%) who has the potentiate of statin drug interactions. The most were simvastatin-amlodipine interactions, occurs in 104 patients (31,14%). This study shows that most statin users are elderly patients. Statin is used not only in dyslipidemia patients. There are many potential statin drug-drug interactions, but the statin dose is low and not over the standard doses. Keyword: dyslipidemia, statins, drug interactions
A study of Knowledge, Attitude and Behaviour on the Use of Natural Medicine for Type 2 Diabetes Mellitus in Pharmacies in Kendal Regency Area Santi Setiani; Maria Caecilia N.Setiawati; Yosef Wijoyo
International Journal of Public Health Vol. 2 No. 4 (2025): December : International Journal of Public Health
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62951/ijph.v2i4.558

Abstract

Diabetes mellitus (DM) is one of the global health challenges that continues to rise, including in Indonesia. However, the lack of education and counseling from pharmacists regarding the use of natural ingredients medicines has the potential to affect the effectiveness of treatment and the management of DM. This study aims to measure the level of knowledge, attitudes, and behaviour of DM patients, related to the use of natural ingredient drugs in DM management. This study uses a cross-sectional method design, starting with the collection of quantitative data. Sampling was conducted using purposive sampling technique over a period of four months. The research involved 101 DM patients from 15 pharmacies in Kendal Regency. The level of knowledge (44.6%), attitude (66.3%), and behaviour (39.6%) of patients in the moderate category. However, the limited knowledge of pharmacists remains a barrier to optimizing pharmaceutical services related to educating patients about natural ingredient medications.