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All Journal Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS) Journal of Pharmaceutical Care Anwar Medika PROFESSIONAL HEALTH JOURNAL Berajah Journal
Siti Nur Asiyah
Universitas Muhammadiyah Gresik
Biochemistry, Genetics & Molecular Biology Chemistry Education Environmental Science Health Professions Languange, Linguistic, Communication & Media Library & Information Science Medicine & Pharmacology Nursing Physics Public Health Social Sciences

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Gambaran Pengelolaan Penyimpanan Obat Di Apotek X Lamongan Vivian Dwi Putri Anjani; Siti Nur Asiyah; Pemta Tiadeka
Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS) Vol 3 No 02 (2022): HERCLIPS VOL 03 NO 02
Publisher : Universitas Muhammadiyah Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30587/herclips.v3i02.3760

Abstract

Apotek X Lamongan is a health service facility that manages supplies in the pharmaceutical sector. Based on preliminary studies that have been carried out, the results show that at Apotek X Lamongan there are often problems in the storage and dispensing of drugs. One of the incidents of wrong drug storage that occurs is not recording the intake and expenditure of drugs. This causes the service to be less than optimal, allegedly because the storage system at the X Lamongan Pharmacy is not fully in accordance with the pharmaceutical service standards at the pharmacy, and there has never been any research on the drug storage system at the X Lamongan Pharmacy. Based on the importance of the impact of drug storage in a pharmacy, it is necessary to evaluate the drug storage system at the X Lamongan Pharmacy. This study aims to evaluate and determine the drug storage system at Apotek X Lamongan. This research is a descriptive observational study by making direct observations of the pharmacy storage system in the form of a checklist and conducting direct interviews with the person in charge of the pharmacy. It shows that in general the drug storage system has a score of 60.41% which is categorized as quite good. The drug storage system includes spatial arrangement with the percentage obtained is 66.67% in the good category, the method of preparation of drugs with a percentage value of 100% in the very good category, recording of stock cards with a percentage value of 0% in the very poor category, and observation of drug quality with a value of 0%. percentage 75% good category. This shows that X Lamongan Pharmacy has not met the storage standards based on Permenkes No. 73 of 2016 and based on BPOM No. 4 of 2018.
DAMPAK PANDEMI COVID-19 TERHADAP PROSES PEMBELAJARAN IPS KELAS IV SD DI DESA PINGGIRAN KABUPATEN GRESIK Siti Nur Asiyah; Arya Setya Nugroho, M.Pd; Afakhrul Masub Bakhtiar, M.Pd
Berajah Journal Vol. 2 No. 4 (2022): November
Publisher : Penerbit Lafadz Jaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/bj.v2i4.161

Abstract

Penelitian ini bertujuan untuk mendapatkan informasi mengenai dampak pandemi Covid-19 terhadap proses pembelajaran IPS kelas IV SD di desa pinggiran Kabupaten Gresik tahun pelajaran 2020/2021. Penelitian ini merupakan penelitian kualitatif yang dilakukan secara observasi, wawancara, angket dengan guru kelas. Desain penelitian ini menggunakan instrumen berupa pedoman wawancara dan observasi yang memuat pertanyaan mengenai dampak yang ditimbulkan oleh pandemi Covid-19 terhadap pembelajaran. Subjek penelitian terdapat sebanyak 6 peserta didik, teknik pengumpulan data menggunakan observasi, wawancara dan angket.
Profil Kesesuaian Resep Pasien Umum Rawat Jalan Terhadap Formularium Rumah Sakit Depo Paviliun RSUD Ibnu Sina siti nur sa'idah; Siti Nur Asiyah; Norainny Yunitasari
Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS) Vol 4 No 01 (2022): Herclips Vol 04 No 01
Publisher : Universitas Muhammadiyah Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30587/herclips.v4i01.3877

Abstract

Kesesuaian resep terhadap formularium mempengaruhi mutu pelayanan rumah sakit. Sesuai dengan Keputusan Menteri Kesehatan RI Nomor 129 Tahun 2008 tentang Standar Pelayanan Minimal Rumah Sakit Bagian Farmasi menyebutkan bahwa standar penulisan resep sesuai dengan formularium adalah 100%. Tujuan penelitian ini adalah untuk mengetahui profil kesesuaian resep pasien umum terhadap formularium rumah sakit di depo paviliun RSUD Ibnu Sina Kabupaten Gresik. Penelitian ini merupakan studi observasional dengan pendekatan deskriptif kuantitatif dan pengumpulan data dilaksanakan secara retrospektif. Populasi yang digunakan adalah semua resep pasien umum yang masuk di depo paviliun selama bulan Januari-Maret 2021. Teknik pengambilan sampel menggunakan random sampling dan didapatkan 162 lembar resep sebagai sampel penelitian. Hasil penelitian menunjukkan bahwa kesesuaian resep terhadap formularium kurang dari 100%. Oleh karena itu perlu dilakukan evaluasi terhadap daftar obat Formularium Rumah Sakit 2018 dan rapat anggota yang terselenggara minimal tiga bulan sekali. Bila perlu, dibuat e-book Forkit dan penulisan resep elektronik, serta reward bagi dokter penulis resep sesuai Forkit Kata kunci: formularium rumah sakit, kesesuaian, penulisan resep
Kajian Kajian In Silico Aktivitas Ekstrak Daun Mangga (Mangifera indica L.) Sebagai Antidiabetes Tipe 2 Janatun naimah; Anindi Lupita Nasyanka; Diah Ratnasari; Siti Nur Asiyah
PROFESSIONAL HEALTH JOURNAL Vol 5 No 1sp (2023): Special Issue Outcome PDP
Publisher : Pusat Penelitian dan Pengabdian Masyarakat (PPPM) STIKES Banyuwangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54832/phj.v5i1sp.500

Abstract

Type 2 diabetes mellitus is the most common type of diabetes in the world. Type 2 diabetes mellitus is caused by an increase in blood sugar due to a decrease in low insulin secretion by the pancreas gland. Pharmacological therapy for type 2 diabetes, namely oral antidiabetic drugs (OAD) or insulin such as acarbose, metformin, or voglibose has been reported to have side effects. Side effects that occur, such as gastrointestinal disturbances (diarrhea and flatulence), liver disorders, dizziness, nausea and vomiting. Thus, herbal ingredients are an alternative in the treatment of diabetes mellitus. In this study, mango leaf extract, namely mangiferin, was suspected as an antidiabetic compound. The purpose of this study was to determine the interaction of mangiferin which is an extract of mango leaves (Mangifera Indica L.) with -glucosidase in silico. The results showed that mangiferin as a type 2 antidiabetic compound by producing an G value between -glucosidase and mangiferin of -38.89 kcal/mol. The interaction that occurs is hydrogen bonding between mangiferin and amino acid residues Glu553, Asn551, Arg500 and Tyr460, Phe461. Keywords: α-glucosidase, in silico, mangiferin, mango leaf,
Studi In silico : Toksisitas Senyawa Potensial Sebagai Antikanker Turunan N-((4-Fluorofenil) Karbamatiol) Benzamida Anindi Lupita Nasyanka; Diah Ratnasari; Jannatun Na'imah; Siti Nur Asiyah
Journal of Pharmaceutical Care Anwar Medika (J-PhAM) Vol 5 No 2 (2023): Journal of Pharmaceutical Care Anwar Medika (J-PhAM)
Publisher : STIKES Rumah Sakit Anwar Medika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36932/jpcam.v5i2.144

Abstract

The potential derivative compound N-((4- Fluorophenyl ) Carbamatiol ) Benzamide a has been predicted to have good activity at the sirtuin-1 receptor which plays a role in triggering cancer on the p53 protein . Toxicity plays a very important role in the safety of the drugs used in the development of new drugs. Therefore, this study aims to determine the toxicity prediction of NBFFT derivatives as anticancer drug candidates. The method used is quantitative descriptive analysis based on the results of in silico toxicity predictions using the Read Across method through the ProTox web server system. on NBFFT derivatives in the ChemBL database with comparators of tenovin and hydroxyurea. The results showed that the derivative compound N-((4 -Fluorophenyl ) carbamatiol ) Benzamide a as an anticancer candidate, it is included in category V (possibly dangerous if consumed) which corresponds to tenovin as a comparison. In addition, predictions of hepatotoxic events were found in these derivative compounds through the MMP stress response pathway, p53, and the nuclear cell nucleus receptor (AhR) type signaling pathway.
Co-Authors Afakhrul Masub Bakhtiar, M.Pd Arya Setya Nugroho, M.Pd Diah Ratnasari Janatun Na’imah Jannatun Na'imah Nasyanka, Anindi Lupita Norainny Yunitasari Pemta Tiadeka siti nur sa'idah Vivian Dwi Putri Anjani