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All Journal Jurnal Indah Sains dan Klinis Mejuajua Medical Sains : Jurnal Ilmiah Kefarmasian
Melati Yulia Kusumastuti
Program Studi Farmasi, Sekolah Tinggi Ilmu Kesehatan Indah Medan, Indonesia
Humanities Chemistry Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Other

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Aktivitas Antibakteri Daun Kemangi (Ekstrak, Fraksi Kloroform, dan Fraksi n-Heksan) terhadap Staphylococcus aureus dan Eschericia coli Melati Yulia Kusumastuti; Debi Meilani; Suhendra Tawarnate
Journal of Indah Science and Clinic Vol. 2 No. 1 (2021)
Publisher : LPPM STIKes Indah Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v2i1.11

Abstract

Basil (Ocimum citriodorum Vis.) is a plant which is their leaves are commonly eaten as fresh vegetables and has many benefits. Basil leaves contains secondary metabolite compounds that have antibacterial activity such as flavonoids, tannins, saponins, alkaloids, and steroids. The purpose of this study was to known the antibacterial activity of some fractions of basil leaves against Escherichia coli and Staphylococcus aureus and see which fraction was more active.This research included extraction by maceration method using ethanol 96%, then ethanol extract was fractionated using n-hexane and chloroform, phytochemical screening, then tested for antibacterial activity against E. coli and S. aureus by using agar diffusion method. Phytochemical screening showed ethanol extract contained alkaloids, saponins, flavonoids, tannins and steroids; chloroform fraction contained alkaloids, flavonoids, saponins, and tannins; and n-hexane fraction contained steroids. The results of the antibacterial activity test showed ethanol extract and chloroform fraction had antibacterial activity. Meanwhile, n-hexane fraction did not have antibacterial activity. Concentration of 500 mg / ml of chloroform fraction and ethanol extract on S. aureus resulted inhibition zone around 24.67-26.90 mm. Furthermore, on E. coli produced 22.67-23.84 mm. Ethanol extract had higher antibacterial activity than the chloroform fraction against E. coli and S. aureus.
Evaluasi Konsentrasi Karboksimetilselulosa-Alginat Formula Pasta Gigi Antiseptik Ekstrak Etanol Daun Seledri (Apium graveolens L.) Suprianto Suprianto; Samran Samran; Muhammad Gunawan; Melati Yulia Kusumastuti
Journal of Indah Science and Clinic Vol. 3 No. 1 (2022)
Publisher : LPPM STIKes Indah Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i1.45

Abstract

Maceration of Celery leaves using 96% ethanol solvent was used to make the extract. Toothpaste is formulated with carboxymethylcellulose and alginate binders. The active ingredient in the form of ethanol extract of Celery leaves has the potential for antibacterial. This study was to evaluate the concentration of carboxymethylcellulose-alginate in the preparation of antiseptic toothpaste of ethanol extract of Celery leaves. Evaluation of production results consisted of organoleptic, homogeneity, spreadability, foam formation, acidity and viscosity. The higher the concentration of carboxymethylcellulose, the lower the foam and spreadability and the higher the viscosity, while the alginate concentration is the opposite. Carboxymethylcellulose-alginate affects the evaluation parameters of antiseptic toothpaste preparations ethanol extract of Celery leaves
Analisis Biaya Efektif Terapi Diare Pasien Rawat Inap RS Putri Hijau Medan Suprianto Suprianto; Muhammad Gunawan; Melati Yulia Kusumastuti; Sumardi Sumardi; Debi Meilani
Journal of Indah Science and Clinic Vol. 3 No. 1 (2022)
Publisher : LPPM STIKes Indah Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i1.46

Abstract

Diare ditandai ekskresi tinja cair dengan ulangan tiga kali atau lebih per hari, akibat infeksi saluran cerna karena makanan dan air terkontaminasi mikroorganisme, ataupun langsung dari manusia akibat rendahnya sanitasi. Penelitian ditujukan untuk mengetahui karakteristik pasien diare, pengobatan dan efektivitas biaya pengobatan di Rumah Sakit Putri Hijau Medan. Penelitian non eksperimental bersifat deskriptif dan retrospektif rekam medik pasien bagian keuangan sejak Juli-Desember 2018. Cost Effectiveness Analysis sebagai metode analisis biaya. Karakteristik pasien diperoleh perempuan 14 (46,670%) dan laki-laki 16 (53,33%). Efektivitas New Diatabs (92,30%) dan New Diatabs-Metronidazole (94,11%). Biaya terapi dengan New Diatabs Rp 1.547,771/pasien dan New Diatabs-Metronidazole Rp 1.562,590/pasien. Average cost effectiveness New Diatabs Rp. 190.345 dan New Diatabs-Metronidazole Rp 183.060, sehingga disimpulkan terapi cost effective adalah penggunaan kombinasi New Diatabs-Metronidazole dibandingkan New Diatabs
Pendampingan Pembuatan Minyak Gosok Berbahan Alami Sari Jahe dan Minyak Pala bagi Ibu PKK Desa Lestari Dadi Serdang Bedagai Suprianto Suprianto; Melati Yulia Kusumastuti; Andilala; Lili Nurmaliza; Ruseni; Sumardi; Samran; Dian Zulkarnain Lubis; Devi Purnama Sari
Mejuajua: Jurnal Pengabdian pada Masyarakat Vol. 1 No. 3 (2022): April 2022
Publisher : Yayasan Penelitian dan Inovasi Sumatera (YPIS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/mejuajuajabdimas.v1i3.31

Abstract

Desa Lestari Dadi berada di wilayah Kecamatan Pegajaha Kabupaten Serdang Bedagai Provinsi Sumatera Utara, sekitar ± 45 km dari kampus STIKes Indah Medan, sebagai objek Pengabdian oleh Tim PKM Program Studi S1 Farmasi STIKes Indah Medan. Ibu-ibu anggota PKK sebagian besar turut membantu suami sebagai petani, terutama petani Padi dan Semangka. Jahe dan Pala menjadi produk sampingan desa Lestari Dadi. Minyak gosok merupakan suatu produk sediaan cair, sangat praktis dan nyaman digunakan oleh konsumen. Pendampingan oleh Tim PKM untuk melatih anggota Ibu PKK Desa Lestari Dadi memproduksi Minyak Gosok Berbahan Alami Sari Jahe dan Minyak Pala (Minyak Gosok Sahe Mila). Ibu-ibu peserta Tim PKK Desa Lestari Dadi mengikuti dengan cukup antusias dan produk Minyak Gosok Sahe Mila sesuai keinginan
Pelatihan Pembuatan Hand Sanitizer Antiseptik Alami Tumbuhan pada Ibu PKK Desa Cinta Rakyat Percut Sei Tuan Cut Fatimah; Muhammad Gunawan; Safriana Safriana; Melati Yulia Kusumastuti; Edi Ananta Tarigan; Rama Asiah Siregar
Mejuajua: Jurnal Pengabdian pada Masyarakat Vol. 1 No. 1 (2021): Agustus 2021
Publisher : Yayasan Penelitian dan Inovasi Sumatera (YPIS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (242.466 KB) | DOI: 10.52622/mejuajuajabdimas.v1i1.10

Abstract

Pandemi Covid-19 merubah struktus dan tatanan kehidupan masyarakat. Peningkatan kasus Covid-19 menyebabkan Pemberlakuan Pembatasan Kegiatan Masyarakat. Masyarakat tidak leluasa beraktivitas dan ekonomi makin terpuruk. Demikian juga masyarakat di desa Cinta Rakyat Percut Sei Tuan, biasa beraktivitas sebagai petani dan nelayan. Ibu rumah tangga membantu suami, belum beraktivitas mandiri dari rumahan, sehingga berpeluang diberi ketrampilan oleh Tim Pengabdian Kepada Masyarakat dari Sekolah Tinggi Ilmu Kesehatan Indah Medan dalam pembuatan Hand Sanitizer antiseptik alami tumbuhan. Pembuatan tidak sulit, berbahan baku murah dan dengan alat sederhana sehingga dapat diproduksi rumahan. Hasil produksi di-manage agar dapat dipasarkan melalui toko, swalayan, dan online. Pengabdian ditujukan melatih pembuatan Hand Sanitizer berbaha tumbuhan. Pendekatan persuasive dilakukan kepada Ibu-ibu untuk mengikuti pelatihan agar lepas dari keterpurukan ekonomi. Hasil pelatihan menunjukkan produk sediaan Hand Sanitizer yang dibuat ibu peserta dikemas dengan baik dan siap untuk dipasakan. Pelatihan bersama dengsn Tim Pengabdian sesuai dengan yang diharapkan peserta.
ANTIDIABETIC EFFECT OF ETHANOLIC EXTRACT OF KEDONGDONG PAGAR LEAVES (Lannea coromandelica (Houtt.) Merr.) ON MALE MICE Safriana Safriana; Melati Yulia Kusumastuti; Andilala Andilala
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 9 No 1 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v9i1.1097

Abstract

Diabetes mellitus is a metabolic condition defined as an increase in blood glucose levels (hyperglycemia) caused by impaired insulin production or insulin action. One of the treatments for diabetes mellitus is the use of medicinal plants because they contain bioactive phytochemicals. Kedongdong pagar leaves (Lannea coromandelica (Houtt.) Merr.) is an empirical medication used to reduce the blood glucose levels in Aceh, Indonesia.  The leaves contain flavonoids, which have antioxidant effects that can reduce damage to the pancreatic beta cells. The goal of this study was to examine the antidiabetic impact of an ethanol extract of kedongdong pagar leaves in male mice induced with alloxan to increase blood glucose levels. The test procedure involved splitting 25 mice into five treatment groups, Na-CMC suspension 0.5% w/v, Kedongdong pagar extract with dose 10 mg/kg BW, 20 mg/kg BW, 40 mg/kg BW, and glibenclamide suspension with dose 0.65 mg/kg BW as positive control. The results showed that all ethanolic extracts of Lannea coromandelica had the same potency to lower blood glucose levels in mice, implying that the ethanol extract of Lannea coromandelica leaves had antidiabetic activity due to the presence of antidiabetic compounds such as flavonoids and glycosides. Keywords: Antidiabetic, Diabetic, Kedongdong Pagar Leaves, Lannea coromandelica.
Co-Authors Andilala Cut Fatimah Debi Meilani Devi Purnama Sari Dian Zulkarnain Lubis Edi Ananta Tarigan Lili Nurmaliza Muhammad Gunawan Rama Asiah Siregar Ruseni Safriana Safriana Samran, Samran Suhendra Tawarnate Sumardi Suprianto Suprianto