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All Journal Jurnal Matematika & Sains Jurnal Biologi Tropis Science Midwifery Jurnal Kesehatan Tambusai Indonesian Journal of Pharmaceutical Education Jurnal Farmasi Tinctura Humantech : Jurnal Ilmiah Multidisiplin Indonesia Journal of Nutrition Science
Donn Richard Ricky
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Religion Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Public Health Veterinary

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Penggunaan Ruang Reaksi Berbentuk Tabung Berdiameter 500 µm untuk Menumbuhkan Nanopartikel ZnO Berdispersi Tunggal Saragih, Horasdia; Ricky, Donn Richard; Limbong, Albinur
Jurnal Matematika dan Sains Vol 18 No 2 (2013)
Publisher : Institut Teknologi Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Nanopartikel ZnO berdispersi tunggal memiliki bidang terapan yang sangat luas karena sangat attraktif serta memiliki efisiensi kerja yang sangat tinggi. Oleh karena itu investigasi terhadap teknik-teknik penumbuhannya terus dilakukan dan mendapat banyak perhatian. Teknik penumbuhan yang efesien dan sederhana, terus dicari. Pada penelitian ini nanopartikel ZnO berdispersi tunggal telah ditumbuhkan dengan menggunakan ruang reaksi berbentuk tabung berjari-jari 500 µm. Sifat sirkulatif bahan cair yang mengalir di dalam tabung dimanfaatkan untuk mendapatkan hasil campuran dan hasil reaksi prekursor yang homogen. Dengan memanfaatkan pola alir prekursor yang sirkulatif serta ukuran volumenya yang sangat kecil di dalam tabung, menghasilkan waktu pencampuran yang sangat singkat dan distribusi ukuran nanopartikel ZnO yang relatif homogen (berdispersi tunggal). Dengan cepatnya proses pencampuran dan dengan homogennya ukuran nanopartikel ZnO yang dihasilkan, membuat teknik penumbuhan ini menjadi sangat efesien dan sederhana. Serbuk ZnCl2, serbuk NaOH dan di-water (H2O) digunakan sebagai prekursor, dan etanol digunakan sebagai pelarut. Polimer polyvinylpyrrolidone (PVP) digunakan sebagai separator untuk memperkecil ukuran rata-rata nanopartikel ZnO dan untuk mempersempit distribusi ukurannya. Kata kunci: Ruang reaksi berbentuk tabung, Nanopartikel ZnO, Dispersi tunggal, Polyvinylpyrrolidone (PVP).   The Use of Tube Reactor with Diameter of 500 µm for Growing ZnO Monodisperse Nanoparticles Abstract ZnO monodisperse nanoparticles have various field applications. This material was very attractive and has high performance. Today, the growth technique of this material with high efecience and simple is intensively investigated and attack much attention. In this work, ZnO monodisperse nanoparticles have been grown with use a reactor in the tube form with diameter of 500 µm. In the tube, precursors were flow circulatively and have very small volume. Due to the flow circulatively and very small volume of precursors in the tube, the homogen mixture of precursors, homogen reactions, and finally, monodisperse of ZnO nanoparticles were obtained in short time. With this reactor, growth of ZnO monodisperse nanoparticles could be carried out simply and efficiently. ZnCl2, NaOH and H2O were used as precursors, and athanol was used as solvent. Polymer polyvinylpyrrolidone (PVP) was used as separator to obtain different average size and different distribution size of ZnO monodisperse nanoparticels.  Keywords: Tube Reactor, ZnO nanoparticles, Monodisperse, Polyvinylpyrrolidone (PVP).
The Extraction and Nano Particles Production of Moringa Leaf Bioactive Compounds and Their Identification Feronyanti Mitranistin Pello; Donn Richard Ricky
Journal of Nutrition Science Vol 4, No 1 (2023): May, 2023
Publisher : Universitas Teuku Umar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35308/jns.v4i1.7553

Abstract

Moringa leaves (Moringa oleifera) is a vegetable plant from the Brassica order and belongs to the Moringaceae family, known as the “Magic Plant” which has a wide variety of protein content contained in it. Therefore, the bioactive compounds used are Moringa leaves (Moringa oleifera) which have such great potential that they can be developed as raw materials for medicine. However, because the secondary metabolite compounds contained by plants have hydrophobic properties. This property can be one of the obstacles for these secondary metabolites to be easily absorbed by the body because of their nature which is difficult to dissolve in body fluids so that they can be easily degraded by the body's enzymatic system, to overcome this problem Nanoparticles can be a solution in overcoming this problem. the manufacture of nanoparticles has been carried out. To produce nanoparticles of Moringa leaf bioactive compounds, synthesized using tween 80 surfactants, has been carried out using the spontaneous emulsion method. The bioactive compounds contained in Moringa leaves (Moringa oleifera) are: (1) 9-Octadecenoic acid (29.64%), (2) Hexadecanoic acid (18.42%), (3) Octadecanoic acid (7.07%), (4) Oleic Acid (5.88%), and (5) 14-Methyl-8-hexadesin-1-ol (5.47%). Synthesis using four different concentrate masses of these compounds, namely: 2 mg, 1.5 mg, 1 mg and 0.5 mg dissolved in 100 ml of ethanol, resulted in an average diameter of each nanoparticle of 15.9 nm; 15.5nm; 14.7nm; and 14.8 nm. The polydispersity index is 0.306; 0.258; 0.122; and 0.282. From the results above, it has been shown that the process of synthesizing nanoparticles of secondary metabolites of ethanol extract using the spontaneous emulsion method has produced small-sized particles. This allows the development of site results to be used in applications in various fields such as in the pharmaceutical field in the drug development process.
Nanoparticles production of bioactive compounds from cardamom fruit ethanol extract Sherlin Marthalina putri Natty; Donn Richard Ricky
Science Midwifery Vol 11 No 2 (2023): June: Midwifery and Health Sciences
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v11i2.1272

Abstract

Research in recent years has focused on developing nanoparticle bioactive compounds extracted from ethanol cardamom due to its potential health benefits. Cardamom (Elettaria cardamomum) is a spice plant commonly used in traditional medicine to treat various health problems, such as digestive disorders, headaches, and respiratory issues. This study explored the method of producing nanoparticles from bioactive compounds of cardamom ethanol extract using gas chromatography-mass spectroscopy (GC-MS) and nanoparticle techniques. The steps for producing nanoparticles through this method consist of several stages, starting with identifying bioactive compounds using GC-MS, followed by producing nanoparticles using Nanoparticle techniques. The measurement results of the prepared chromatography concentrates were performed using Shimadzu GC-MS QP2010 Ultra equipment, and the total ion chromatogram (TIC) of the measured compound molecules was obtained. This study found that the size or percentage of each peak area in the concentrate correlates with the high order of the peak, thus indicating the compound content in the concentrate.
Evaluasi Rasionalitas Penggunaan Antibiotik pada Neonatus dengan Infeksi Pneumonia Menggunakan Metode Gyssens di Rumah Sakit X Kota Bandung Charisma Juni Kristianti; Duma Turu Allo; Donn Ricky
Indonesian Journal of Pharmaceutical Education Vol 3, No 3 (2023): September-Desember 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i3.22370

Abstract

Pneumonia is an inflammation of the lung tissue which is usually caused by a bacterial, viral or fungal infection. The disease can affect individuals of any age group, however, children, the elderly, and individuals with weakened immune systems are susceptible to potentially life-threatening pneumonia. Treatment therapy that is often carried out in overcoming the problem of pneumonia infection is by administering antibiotics. Inappropriate administration of antibiotics can cause less effective treatment, increase the risk of nosocomial infections, increase resistance, and side effects of drugs that are harmful to health. Rational use of antibiotics is important to avoid these negative consequences. The aim of this study was to determine the quality of antibiotic use in neonatal patients with pneumonia infections using the Gyssens method approach at Hospital Evaluation of antibiotic use was analyzed using Microsoft Excel. Retrospective design with data collection. Data analysis uses the Gyssens method flow diagram. The results showed that antibiotic use included Amikacin (15%), Amoxicillin (15%), Ampicillin (2%), Ampicillin Sulbactam (19%), Cefotaxime (19%), Ceftazidime (3%), Ceftriaxone (1%), Gentamicin(14%), Imipenem Cilastatin(1%), Meropenem(11%), Metronidazole(8%), Netilmicin(1%), Vancomycin(5%). Based on the research results, the conclusion of this study shows that the irrational use of antibiotics is a serious problem that requires immediate attention and joint action to protect the effectiveness of antibiotics and overall public health.
EVALUASI PENGGUNAAN ANTIBIOTIK PADA PASIEN PNEUMONIA DENGAN METODE GYSSEN DI RUMAH SAKIT SWASTA DI BANDUNG Cynthia Anggreani Simbolon; Duma Turu Allo; Donn Richard Ricky
Jurnal Kesehatan Tambusai Vol. 4 No. 4 (2023): DESEMBER 2023
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v4i4.20039

Abstract

Penelitian ini bertujuan untuk mengkaji penggunaan antibiotik pada pasien yang mengidap pneumonia dengan menerapkan metode Gyssens di sebuah Rumah Sakit Swasta di Bandung. Penelitian ini menerapkan metode penelitian retrospektif dengan menghimpun data sekunder dari catatan medis pasien yang mengalami pneumonia di Rumah Sakit Swasta tersebut selama periode Januari hingga Desember 2022. Hasil penelitian menunjukkan bahwa sebanyak 125 pasien pneumonia di Rumah Sakit Swasta Bandung periode Januari-Desember 2022 menerima antibiotik dengan metode Gyssens. Dari jumlah tersebut, 72 pasien memenuhi kriteria inklusi. Dalam kelompok pasien ini, terdapat 34 pasien laki-laki (47%) dan 38 pasien perempuan (53%). Lebih banyak pasien yang mengalami pneumonia berusia di atas 65 tahun, yaitu sebanyak 8 orang (32%), diikuti oleh kelompok usia 56 hingga 65 tahun sebanyak 6 orang. Durasi penggunaan antibiotik bervariasi, dengan 30 pasien menerima terapi selama 1-4 hari, 28 pasien selama 5-7 hari, dan 14 pasien selama 8-20 hari. Jenis Antibiotik yang paling umum diberikan adalah ceftriaxone. (sebanyak 18%) dari golongan cefalosporin generasi III, dan levofloxacin (sebanyak 32%) dari golongan fluorokuinolon. Hasil evaluasi penggunaan antibiotik dengan metode Gyssens menunjukkan bahwa 46 penggunaan (40%) masuk dalam kategori 0, sementara 68 penggunaan (60%) masuk dalam kategori 1.
IDENTIFIKASI SENYAWA BIOAKTIF EKSTRAK ETANOL DAN METANOL JAHE MERAH (Zingiber officinale var.Rubrum) DENGAN MENGGUNAKAN GAS CHROMATOGRAPHY-MASS SPECTROMETER Masnaria Situmorang; Donn R. Ricky
Humantech : Jurnal Ilmiah Multidisiplin Indonesia Vol. 2 No. 01 (2022): Humantech : Jurnal Ilmiah Multidisiplin Indonesia
Publisher : Program Studi Akuntansi IKOPIN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32670/ht.v2i01.1071

Abstract

Dalam penelitian ini kami melaporkan hasil kandungan senyawa bioaktif Zingiber officinale var. Rubrum yang telah dievaluasi menggunakan Shimadzu GCMS-QP2010 Ultra. Ekstra jahe merah 250 g dilarutkan dengan pelarut etanol dan methanol 96% sebanyak 400ml hasil ekstrak jahe merah difilter dengan menggunakan kertas saring whatman no 1 sesudah itu didiamkan selama 4 jam. Maserat dipisahkan dan diuapkan melalui evaporasi selama 1 jam pada temperature 60\degc. Untuk metode analisis GC-MS ekstra jahe merah dilakukan dengan suhu oven sebesar 100.0\degc dengan mode injeksi split pada suhu injeksi temperatur 300.00\degc. Dari hasil percobaan methanol menggunakan GC-MS maka diperoleh senyawa benzene (24.07%), senyawa zingiberene (34.69%), senyawa farnesene (5.94%), senyawa \beta-Bisabolene (14.73%), dan senyawa terakhir yaitu senyawa \beta-Sesquiphellandrene (20.57%). Sedangkan pada pelaurut etanol terdapat senyawa Benzene (26.35%), senyawa Zingiberene (37.68%), senyawa \beta-BisaboleneCyclohexene (16.13%), senyawa \beta-Sesquiphellandrene (19.84%). Hasil GC-MS kandungan bioaktif dengan menggunakan perbandingan pada pelarut etanol dan methanol maka terdapat kandungan senyawa tertinggi dari kedua pelarut yaitu, senyawa zingiberene dengan waktu retensi 9.675 pada pelarut methanol dan waktu retensi 9.677 pada pelarut etanol.
Identifikasi senyawa bioaktif ekstrak metanol sereh wangi (cymbopogon nardus) dengan menggunakan gas chromatography-mass spectrometer Simbolon, Gladys Renata; Donn R. Ricky
Humantech : Jurnal Ilmiah Multidisiplin Indonesia Vol. 2 No. 3 (2022): Humantech : Jurnal Ilmiah Multidisiplin Indonesia
Publisher : Program Studi Akuntansi IKOPIN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32670/ht.v2i3.1484

Abstract

The need for essential oils is increasing along with the increasing development of modern industries such as the perfume, cosmetic, pharmaceutical, food, aromatherapy and drug industries (Ella et al, 2013). Citronella is processed and processed to obtain pure essential oil so that it gets a high selling value, and research is carried out to identify GC-MS using 100 grams of citronella extract with the extraction process using 500 ml of methol solvent and evaporated for 25 minutes at 60°C. The results of GC-MS got the components from the highest to the lowest, namely the highest compound was hydroxymethyl of 33.40% with a retention of 6,500 minutes, the second highest compound was nonadecane of 29.47% with a retention of 23,559 minutes, the third highest compound was dodecanoic of 14.51 with a retention of 22.863 minutes, the fourth compound was pyran. of 13.31 with a retention of 5.333 minutes, and the lowest compound is dodecanoic of 9.31 with a retention of 23,333 minutes. From the results of the identification test of citronella extract using methanol as a solvent, the highest compound component is the hydroxymethyl group, this compound has several functions, namely, as an antioxidant and anti-microbial.
Antibacterial Effectiveness Test of Roselle Flower (Hibiscus sabdariffa L.) Ethanol Extract Against Escherichia coli, Staphylococcus aureus, and Propionibacterium acnes Bacteria Nababan, Febryanti; Panjaitan, Ivonne M. S.; Ricky, Donn Richard
Jurnal Biologi Tropis Vol. 25 No. 1 (2025): Januari - Maret
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i1.8765

Abstract

Bacterial infections are a growing global health challenge, especially with the increasing cases of antibiotic resistance. This study used a true experimental method with a posttest-only control group design to investigate the antibacterial efficacy of roselle flower (Hibiscus sabdariffa L.) ethanol extract against the bacteria Staphylococcus aureus, Escherichia coli, and Propionibacterium acnes. The maceration method was used to extract the roselle flowers using 70% ethanol as the solvent, and the disc diffusion method was used to test for antibacterial activity at extract concentrations of 30%, 40%, and 50%, using the antibiotic chloramphenicol as a positive control. The results showed that the roselle flower ethanol extract exhibited antibacterial activity against all three test bacteria. The highest inhibition zone against E. coli was found at 50% concentration (9.87 mm), classified as moderate. For S. aureus, the 50% concentration produced the highest inhibition zone (18.13 mm) with strong classification, while 30% and 40% concentrations also demonstrated strong inhibitory effects. For P. acnes, all extract concentrations showed strong inhibitory responses with the highest inhibition zone at 50% concentration. Chloramphenicol antibiotic consistently demonstrated higher antibacterial activity across all test bacteria. Statistical analysis revealed significant differences in inhibitory effectiveness based on extract concentration and bacterial type (p<0.001), with a significant interaction between these two factors (η²=0.605). These findings indicate the potential development of roselle flower ethanol extract as a natural antibacterial agent, although further optimization is needed to enhance its effectiveness.
The Effect of Bokashi from Goat Manure and Human Urine on the Growth of Lettuce (Lactuca sativa L) in Deep Flow Technique (DFT) System Dedi, Ronaldus; Situmeang, Doli; Ricky, Donn Richard
Jurnal Biologi Tropis Vol. 25 No. 1 (2025): Januari - Maret
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i1.8766

Abstract

In the pursuit of innovative agricultural practices, the Deep Flow Technique (DFT) hydroponic system has gained popularity to meet the increasing demand for vegetables, such as lettuce. However, finding effective organic fertilizers remains a challenge. This study aimed to investigate the impact of using bokashi from goat manure and human urine on lettuce growth within the DFT system, comparing it to the commonly used AB Mix fertilizer. The experiment observed growth parameters, including root length, number of leaflets, and leaf width, for a period of 28 days. The results indicated that the AB Mix fertilizer yielded the best growth, followed by a combination of goat manure bokashi and human urine, whereas human urine alone resulted in the lowest growth. Statistical analysis confirmed the significant influence of the fertilizer treatments on plant growth. These findings suggest that while AB Mix fertilizer is the optimal choice, the combination of goat manure bokashi and human urine proves to be a viable alternative for organic fertilizer.
Potential of Organic Liquid Fertilizer from Rice Washing Water and Goat Urine on The Growth of Pak Choi (Brassica rapa L. var. Chinensis) Using Hydroponic Method Claudia, Ellen; Ricky, Donn Richard; Tobing, Joshua H. L.
Jurnal Biologi Tropis Vol. 25 No. 1 (2025): Januari - Maret
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i1.8791

Abstract

Hydroponics, an emerging agricultural technology, allows cultivation without soil, but using nutrient-rich water instead. This is promising for future agriculture, as it can be applied in various locations and offers higher quality production results, thus increasing market competitiveness. In addition, waste materials such as rice washing water and goat urine can be reused as valuable organic fertilizers. Rice washing water, rich in nutrients such as vitamin B1, phosphorus, calcium, and nitrogen, serves as a liquid organic fertilizer that promotes superior plant growth. Goat urine, containing natural phytohormones, supports root and shoot development, making it a useful alternative to organic fertilizers. Research shows that liquid organic fertilizers are often preferred over synthetic options in hydroponic systems due to their higher bioactive compound content and environmental safety. This study focuses on the cultivation of Pak Choi (Brassica rapa var. Chinensis) using various nutrient treatments, including rice washing water, goat urine, and AB Mix, with measured concentrations ranging from 1000 to 1400 Part Per Millions (PPM). The results showed significant differences in growth among the treatment groups, with AB Mix producing the highest plant height, number of leaves, and leaf width, indicating the effectiveness of nutrient type on plant development.
Co-Authors Albinur Limbong, Albinur Charisma Juni Kristianti Claudia, Ellen Cynthia Anggreani Simbolon Dedi, Ronaldus Duma Turu Allo Duma Turu Allo Feronyanti Mitranistin Pello Horasdia Saragih Joshua H. L. Tobing Masnaria Situmorang Nababan, Febryanti Panjaitan, Ivonne M. S. Pony Siti Afriyanti Sherlin Marthalina putri Natty Simbolon, Gladys Renata Situmeang, Doli Suak, Raffael Griffin Frarie Tnunay, Fiona Rosslyn Tobing, Joshua Hamonangan Lumban