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All Journal Majalah Kedokteran Bandung Althea Medical Journal Jurnal Farmasi Klinik Indonesia Majalah Patologi Indonesia JK Unila (Jurnal Kedokteran Universitas Lampung) Indonesian Journal of Cancer
Herry Yulianti
Departemen Patologi Anatomi Fakultas Kedokteran Universitas Padjadjaran Rumah Sakit Dr. Hasan Sadikin Bandung
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Journal : Althea Medical Journal

 1 
Effects of White Turmeric Infusion on the Liver Cells in Carbon Tetrachloride-Induced Mice Oktaviani, Fitria; Herdiningrat, RB. Soeherman; Yulianti, Herry
Althea Medical Journal Vol 2, No 4 (2015)
Publisher : Althea Medical Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (494.69 KB)

Abstract

Background: The liver is an organ that has important functions in the body. Liver damage can be caused by oxidative stress and free radicals. White turmeric (Curcuma zedoaria L) contains antioxidants that can be used to neutralize the effects of free radicals. This study was conducted to determine the effect of white turmeric infusion on histological appearance of liver cells in male mice induced by carbon tetrachloride (CCl4).Methods: This laboratory experimental study was conducted using male mice (Mus musculus) with Balb/c strain. Thirty-three mice were randomly divided into 3 groups i.e.,group 1 as a control group was given standard food and drink, group 2 was given 10% of CCl4 0.1 ml by intraperitoneal injection on the first day and group 3 was given 10% of CCl4 0.1 mL by  ntraperitoneal injection on the first day, followed by the administration of 50% of white turmeric infusion 0.2 mL. Kruskal-Wallis test method was used to analyse the significant differences of the average percentage of damaged liver cells in the group given CCl4 alone with the group given CCl4 and white turmeric infusion and control group.Results: The percentage of damaged liver cells between groups of mice given CCl4 alone and the group given CCl4 followed by white turmeric infusion were respectively(p <0.05) compared to group1.Conclusions: Administration of white turmeric infusion gave an influence by decreasing the percentage of damaged liver cells in CCl4-induced mice. White turmeric can serve as an alternative antioxidants that can be used to neutralize the effects of free radicals. [AMJ.2015;2(4):506–10] DOI: 10.15850/amj.v2n4.498
Histopathologic Distribution of Appendicitis at Dr. Hasan Sadikin General Hospital, Bandung, Indonesia, in 2012 Zhafira, Tara; Yulianti, Herry; Wastaman, Maman
Althea Medical Journal Vol 4, No 1 (2017)
Publisher : Althea Medical Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (581.898 KB)

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Background: Appendicitis is a medical emergency and a common cause of emergency surgeries worldwide. Its frequency is varied based on many factors, including age and sex. Histopathologic examination is a gold standard for diagnosis, and complications like gangrene formation and perforation lead to high mortality and morbidity in almost all age groups. This study was conducted to describe the distribution pattern of appendicitis according to age, sex, and histopathologic type. Methods: This cross-sectional study was carried out in the Department of Pathology Anatomy, Dr. Hasan Sadikin General Hospital, Bandung, Indonesia, from August–October 2013. Secondary data were obtained from medical records of January 1st to December 31st, 2012. A total of 503 out of 516 cases were included to be reviewed. Age, sex, and histopathologic type from medical records were then evaluated. Any specific case and perforation were also noted.Results: Data showed the highest prevalence of appendicitis occurred in the 10- 19 age group (28.4%) and in the female group (52.3%). Acute appendicitis was more common than chronic appendicitis in both sexes and all age groups. Perforation rate was high (41.4%), and was more prevalent in male (54.9%) and in the 0–9 age group (65.7%).Conclusions: Appendicitis, both acute and chronic, is more distributed in the second decade, and is slightly more prevalent in females. Acute cases are more common than chronic. Perforation rate is significant and peaks in the first decade and in males. [AMJ.2017;4(1):36–41]DOI: 10.15850/amj.v4n1.1017
Histopathologic Distribution of Appendicitis at Dr. Hasan Sadikin General Hospital, Bandung, Indonesia, in 2012 Tara Zhafira; Herry Yulianti; Maman Wastaman
Althea Medical Journal Vol 4, No 1 (2017)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (581.898 KB)

Abstract

Background: Appendicitis is a medical emergency and a common cause of emergency surgeries worldwide. Its frequency is varied based on many factors, including age and sex. Histopathologic examination is a gold standard for diagnosis, and complications like gangrene formation and perforation lead to high mortality and morbidity in almost all age groups. This study was conducted to describe the distribution pattern of appendicitis according to age, sex, and histopathologic type. Methods: This cross-sectional study was carried out in the Department of Pathology Anatomy, Dr. Hasan Sadikin General Hospital, Bandung, Indonesia, from August–October 2013. Secondary data were obtained from medical records of January 1st to December 31st, 2012. A total of 503 out of 516 cases were included to be reviewed. Age, sex, and histopathologic type from medical records were then evaluated. Any specific case and perforation were also noted.Results: Data showed the highest prevalence of appendicitis occurred in the 10- 19 age group (28.4%) and in the female group (52.3%). Acute appendicitis was more common than chronic appendicitis in both sexes and all age groups. Perforation rate was high (41.4%), and was more prevalent in male (54.9%) and in the 0–9 age group (65.7%).Conclusions: Appendicitis, both acute and chronic, is more distributed in the second decade, and is slightly more prevalent in females. Acute cases are more common than chronic. Perforation rate is significant and peaks in the first decade and in males. [AMJ.2017;4(1):36–41]DOI: 10.15850/amj.v4n1.1017
Effects of White Turmeric Infusion on the Liver Cells in Carbon Tetrachloride-Induced Mice Fitria Oktaviani; RB. Soeherman Herdiningrat; Herry Yulianti
Althea Medical Journal Vol 2, No 4 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (494.69 KB)

Abstract

Background: The liver is an organ that has important functions in the body. Liver damage can be caused by oxidative stress and free radicals. White turmeric (Curcuma zedoaria L) contains antioxidants that can be used to neutralize the effects of free radicals. This study was conducted to determine the effect of white turmeric infusion on histological appearance of liver cells in male mice induced by carbon tetrachloride (CCl4).Methods: This laboratory experimental study was conducted using male mice (Mus musculus) with Balb/c strain. Thirty-three mice were randomly divided into 3 groups i.e.,group 1 as a control group was given standard food and drink, group 2 was given 10% of CCl4 0.1 ml by intraperitoneal injection on the first day and group 3 was given 10% of CCl4 0.1 mL by  ntraperitoneal injection on the first day, followed by the administration of 50% of white turmeric infusion 0.2 mL. Kruskal-Wallis test method was used to analyse the significant differences of the average percentage of damaged liver cells in the group given CCl4 alone with the group given CCl4 and white turmeric infusion and control group.Results: The percentage of damaged liver cells between groups of mice given CCl4 alone and the group given CCl4 followed by white turmeric infusion were respectively(p <0.05) compared to group1.Conclusions: Administration of white turmeric infusion gave an influence by decreasing the percentage of damaged liver cells in CCl4-induced mice. White turmeric can serve as an alternative antioxidants that can be used to neutralize the effects of free radicals. [AMJ.2015;2(4):506–10] DOI: 10.15850/amj.v2n4.498
Co-Authors Abdul Hadi Hassan Abdul Hadi Hassan, Abdul Hadi Adji Kusumadjati Afiati Afiati Afiati Aminah, Hermin Aminah, Hermin Bethy S Hernowo Bethy S. Hernowo Bethy S. Hernowo Bethy S. Hernowo Bethy Surjawathy Hernowo, PhD, SpPA(K) Bethy Suryawathy Hernowo Bethy Suryawati Hernowo Eny Soesilowati Eny Soesilowati Erida, Yulie Erida, Yulie Fitria Oktaviani Fitria Oktaviani, Fitria Hasrayati Agustina Hermin A. Usman Hermin Aminah Hermin Aminah Hermin Aminah Usman Hernowo, PhD, SpPA(K), Bethy Surjawathy Ichfa Namira Maharani Tasyandita, Raina Maman Wastaman RB. Soeherman Herdiningrat Retno Westiningrum Soesilowati, Eny Sri Dharmayanti Suryawathy Hernowo, Bethy Tara Zhafira Usman, Hermin A. Wastaman, Maman Westiningrum, Retno Yasni Iryani Widiasih Yulie Erida Zhafira, Tara