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All Journal Buletin Ilmiah Nagari Membangun Cermin Dunia Kedokteran Cermin Dunia Kedokteran
Dewi Rusnita
Bagian Anatomi, Fakultas Kedokteran Universitas Andalas , Padang, Sumatera Barat, Indonesia
Agriculture, Biological Sciences & Forestry Humanities Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Veterinary Other

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Hasil Pengobatan Adjuvan Tamoksifen pada Pasien Kanker Payudara di RSUP Dr. M. Djamil Padang Muhammad Fadhil; Wirsma Arif Harahap; Dewi Rusnita
Cermin Dunia Kedokteran Vol 46, No 12 (2019): Kardiovaskular
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v46i12.395

Abstract

Kanker payudara merupakan kanker yang paling banyak pada perempuan di dunia. Pada beberapa dekade terakhir, pengobatan adjuvan tamoksifen banyak digunakan. Penelitian ini bertujuan mengevaluasi disease-free survival, survival rate dan efek samping pengobatan tamoksifen. Penelitian deskriptif retrospektif pada bulan September hingga Desember 2016 di RSUP Dr. M. Djamil Padang menggunakan data sekunder 100 sampel dari rekam medik bagian Bedah Onkologi RSUP Dr. M. Djamil Padang dan data primer melalui wawancara. Analisis secara univariat dan metode Kaplan-Meier. Hasil penelitian ini didapatkan kelompok usia terbanyak adalah 50-59 tahun dengan rerata 52,3 tahun. Disease-free survival 5 tahun adalah 0,727 dan survival rate 5 tahun adalah 0,777. Efek samping paling banyak adalah hot-flashes 65%. Terdapat hubungan antara efek samping pengobatan tamoksifen dengan disease free survival dengan nilai p=0,001 (p < 0,05) kekuatan hubungan sedang (r=0,376).Breast cancer is the most commonly diagnosed cancer among women worldwide. For the last few decades, adjuvant tamoxifen is the most preferred therapy. This research aims to evaluate the disease-free survival, survival rate, and side effects of tamoxifen therapy. This retrospective descriptive research was conducted in September until December 2016 at Dr. M. Djamil Padang Hospital using 100 secondary data samples from medical records of Surgical Oncology Dept., Dr. M. Djamil Padang Hospital and primary data through interviews. Univariate analysis and Kaplan-Meier method are used. The result shows that the largest age group is 50-59 years old with average 52,3 years old. The 5-year disease-free survival is 0,727 and 5-year survival rate is 0,777, the most frequent side effect is hot flashes 65%. There is medium strength of the relationship (r = 0,376) between side effects of tamoxifen treatment with disease free survival (p = 0,001 <0,05). 
Hasil Pengobatan Adjuvan Tamoxifen pada Pasien Kanker Payudara di RSUP Dr. M. Djamil Padang Muhammad Fadhil; Wirsma Arif Harahap; Dewi Rusnita
Cermin Dunia Kedokteran Vol 46 No 12 (2019): Kardiovakular
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v46i12.392

Abstract

Kanker payudara merupakan kanker yang paling banyak pada perempuan di dunia. Pada beberapa dekade terakhir, pengobatan adjuvan tamoxifen banyak digunakan. Penelitian ini bertujuan mengevaluasi disease-free survival, survival rate, dan efek samping pengobatan tamoxifen. Penelitian deskriptif retrospektif pada bulan September hingga Desember 2016 di RSUP Dr. M. Djamil Padang menggunakan data sekunder 100 sampel dari rekam medik bagian Bedah Onkologi RSUP Dr. M. Djamil Padang dan data primer melalui wawancara. Analisis dilakukan secara univariat dan metode Kaplan-Meier. Hasil penelitian ini didapatkan kelompok usia terbanyak adalah 50-59 tahun dengan rata-rata 52,3 tahun. Disease-free survival 5 tahun adalah 0,727 dan survival rate 5 tahun adalah 0,777. Efek samping paling banyak adalah hot flush (65%). Terdapat hubungan antara efek samping pengobatan tamoxifen dan disease free survival dengan nilai p=0,001 (p < 0,05) kekuatan hubungan sedang (r=0,376). Breast cancer is the most commonly diagnosed cancer among women worldwide. For the last few decades, adjuvant tamoxifen is the most preferred therapy. This research aims to evaluate the disease-free survival, survival rate, and side effects of tamoxifen therapy. This retrospective descriptive research was conducted in September until December 2016 at Dr. M. Djamil Padang Hospital using 100 secondary data samples from medical records of Surgical Oncology Dept., Dr. M. Djamil Padang Hospital and primary data through interviews. Univariate analysis and Kaplan-Meier method are used. The result shows that the largest age group is 50-59 years old with average 52.3 years old. The 5-year disease-free survival is 0.727 and 5-year survival rate is 0.777, the most frequent side effect is hot flush (65%). There is medium strength of the relationship (r = 0.376) between side effects of tamoxifen treatment with disease-free survival (p = 0.001 <0.05).
UPAYA PENINGKATAN PENGETAHUAN ORANG TUA TERHADAP ZINC DAN PEMBERIAN ZINC KEPADA SISWA SD BUSTANUL ULUM PADANG Siti Nurhajjah; Nur Afrinin Syah; Afdal Afdal; Dewi Rusnita; Tofrizal Tofrizal; Dwisari Dillasamola; Desmawati Desmawati
BULETIN ILMIAH NAGARI MEMBANGUN Vol. 4 No. 1 (2021)
Publisher : LPPM (Institute for Research and Community Services) Universitas Andalas Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/bina.v4i1.288

Abstract

Zinc is an essential micronutrient in the human body as a cofactor of about 300 enzymes. Zinc is very instrumental in the growth process, including maintaining the thymus so that atrophy is not fast. Zinc deficiency can affect the immune system. Zinc deficiency can be caused due to a lack of zinc intake. In theory, many factors affect zinc intake, among others, community knowledge, education, economy, diet, habits, and customs. Lambung Bukit Village is a fostered village of Andalas University. Most people in this village are classified as economically deficient because the community generally farms. The level of public knowledge about zinc is still lacking. This service aims to increase public knowledge of the importance of zinc on body health and the provision of zinc supplements to prevent zinc deficiency and is expected to reduce morbidity and mortality due to infection in children. This activity has been carried out at Bustanul Ulum Elementary School in Batu Busuk Village, Lambung Bukit Village, Pauh District, Padang City. Counseling conducted to 48 people (parents of students and teachers). Almost all parents' knowledge is lacking about zinc, the role, source of zinc, and its relation to several diseases. We hope this counseling can increase public knowledge about the importance of zinc on the body, mainly to prevent susceptibility to infections and any food sources that contain zinc. The results of a health examination by pediatricians found two students suffering from Congenital Heart Disease (CHD), poor oral hygiene, and many teeth carious students. Giving zinc syrup to children aged 7-10 years is expected to prevent zinc deficiency in children.
Hasil Pengobatan Adjuvan Tamoxifen pada Pasien Kanker Payudara di RSUP Dr. M. Djamil Padang Muhammad Fadhil; Wirsma Arif Harahap; Dewi Rusnita
Cermin Dunia Kedokteran Vol 46 No 12 (2019): Kardiovakular
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v46i12.392

Abstract

Kanker payudara merupakan kanker yang paling banyak pada perempuan di dunia. Pada beberapa dekade terakhir, pengobatan adjuvan tamoxifen banyak digunakan. Penelitian ini bertujuan mengevaluasi disease-free survival, survival rate, dan efek samping pengobatan tamoxifen. Penelitian deskriptif retrospektif pada bulan September hingga Desember 2016 di RSUP Dr. M. Djamil Padang menggunakan data sekunder 100 sampel dari rekam medik bagian Bedah Onkologi RSUP Dr. M. Djamil Padang dan data primer melalui wawancara. Analisis dilakukan secara univariat dan metode Kaplan-Meier. Hasil penelitian ini didapatkan kelompok usia terbanyak adalah 50-59 tahun dengan rata-rata 52,3 tahun. Disease-free survival 5 tahun adalah 0,727 dan survival rate 5 tahun adalah 0,777. Efek samping paling banyak adalah hot flush (65%). Terdapat hubungan antara efek samping pengobatan tamoxifen dan disease free survival dengan nilai p=0,001 (p < 0,05) kekuatan hubungan sedang (r=0,376). Breast cancer is the most commonly diagnosed cancer among women worldwide. For the last few decades, adjuvant tamoxifen is the most preferred therapy. This research aims to evaluate the disease-free survival, survival rate, and side effects of tamoxifen therapy. This retrospective descriptive research was conducted in September until December 2016 at Dr. M. Djamil Padang Hospital using 100 secondary data samples from medical records of Surgical Oncology Dept., Dr. M. Djamil Padang Hospital and primary data through interviews. Univariate analysis and Kaplan-Meier method are used. The result shows that the largest age group is 50-59 years old with average 52.3 years old. The 5-year disease-free survival is 0.727 and 5-year survival rate is 0.777, the most frequent side effect is hot flush (65%). There is medium strength of the relationship (r = 0.376) between side effects of tamoxifen treatment with disease-free survival (p = 0.001 <0.05).
Co-Authors Afdal Afdal Desmawati Desmawati Dwisari Dillasamola Muhammad Fadhil Nur Afrinin Syah Siti Nurhajjah Tofrizal Tofrizal Wirsma Arif Harahap