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All Journal JSFK (Jurnal Sains Farmasi & Klinis) Jurnal Hilirisasi IPTEKS (JHI) Buletin Ilmiah Nagari Membangun Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks JAFP (Jurnal Akademi Farmasi Prayoga) Pharmaceutical Sciences and Research (PSR) Jurnal Pengabdian Harapan Ibu (JPHI) Journal of Public Health and Pharmacy Jurnal Sains Farmasi dan Kesehatan

Dwisari Dillasamola

FAKULTAS FARMASI UNIVERSITAS ANDALAS

Author-ID : 3802537

Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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UPAYA PENINGKATAN PENGETAHUAN ORANG TUA TERHADAP ZINC DAN PEMBERIAN ZINC KEPADA SISWA SD BUSTANUL ULUM PADANG Siti Nurhajjah; Nur Afrinin Syah; Afdal Afdal; Dewi Rusnita; Tofrizal Tofrizal; Dwisari Dillasamola; Desmawati Desmawati
BULETIN ILMIAH NAGARI MEMBANGUN Vol 4 No 1 (2021)
Publisher : LPPM (Institute for Research and Community Services) Universitas Andalas Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/bina.v4i1.288

Zinc is an essential micronutrient in the human body as a cofactor of about 300 enzymes. Zinc is very instrumental in the growth process, including maintaining the thymus so that atrophy is not fast. Zinc deficiency can affect the immune system. Zinc deficiency can be caused due to a lack of zinc intake. In theory, many factors affect zinc intake, among others, community knowledge, education, economy, diet, habits, and customs. Lambung Bukit Village is a fostered village of Andalas University. Most people in this village are classified as economically deficient because the community generally farms. The level of public knowledge about zinc is still lacking. This service aims to increase public knowledge of the importance of zinc on body health and the provision of zinc supplements to prevent zinc deficiency and is expected to reduce morbidity and mortality due to infection in children. This activity has been carried out at Bustanul Ulum Elementary School in Batu Busuk Village, Lambung Bukit Village, Pauh District, Padang City. Counseling conducted to 48 people (parents of students and teachers). Almost all parents' knowledge is lacking about zinc, the role, source of zinc, and its relation to several diseases. We hope this counseling can increase public knowledge about the importance of zinc on the body, mainly to prevent susceptibility to infections and any food sources that contain zinc. The results of a health examination by pediatricians found two students suffering from Congenital Heart Disease (CHD), poor oral hygiene, and many teeth carious students. Giving zinc syrup to children aged 7-10 years is expected to prevent zinc deficiency in children.

Pengaruh Ekstrak Etanol Daun Vernonia amygdalina, Del terhadap Kadar Kreatinin Serum Mencit Putih Jantan Suryati Suryati; Dwisari Dillasamola; Fridhani Rahadiant
Jurnal Sains Farmasi & Klinis Vol 3, No 1 (2016): J Sains Farm Klin 3(1), November 2016
Publisher : Fakultas Farmasi Universitas Andalas

Vernonia amygdalina, Del leaves which are locally known as Afrika Selatan leaves used as traditional medicine for diabetes, fever, hypertension and uric acid. A study on the effect of their ethanolic extract on serum creatinin level of male white mice has been done. A twenty of male white mice were divided into four groups which were control group and three test group (A, B, C) which given extract with dose 100 mg/kg BW, 200 mg/kgBW and 400 mg/kgBW respectively. Test group were given extract orally for 21 days. The mice neck was cut and their blood collected at 7th, 14th and 21st day. The serum creatinin level was measured by using spectrophotometer UV-Visible at 492 nm. The result showed all doses of ethanolic extract gave statistically difference on the serum creatinin level (p<0.05). The doses at 400 mg/kgBW showed the most effective in reducing serum creatinin level.

Uji Efek Teratogenik dari Yoghurt Terhadap Fetus Mencit Putih (Mus musculus) Dwisari Dillasamola; Almahdy A; Amirah Desri; Skunda Diliarosta
Jurnal Sains Farmasi & Klinis Vol 5, No 1 (2018): J Sains Farm Klin 5(1), April 2018
Publisher : Fakultas Farmasi Universitas Andalas

Yogurt is one of the dairy products made from lactic acid fermentation by using Lactobacillus bulgaricus and Streptococcus thermophilus. A study on teratogenic effects of yogurt on the white female mice fetus (Mus musculus) has been carried out. Pregnant mice used were 20 which divided into 4 groups : the control group, D1, D2, and D3. The treatments giveThe mice were Distidelled water (control), 0.52 yogurt (D1), 1.04 yogurt (D2), and 2.08 g yogurt (D3). Data were analyzed using one-way ANOVA followed by Duncan multiple range test. Results showed that administration of yogurt during pregnancy could affect mother body weight of mice (P < 0,05).The administration of yogurt during pregnancy did not affect the number of fetuses and fetal body weight significantly (P > 0,05). Observations with Alizarin solution did not show skeletal defects in comparison to the control group. Observations with Bouin’s solution showed defective visceral cleft palate in fetal mice yogurt group D3. This study conclude that yogurt is safe to consume in groups D1 and D2. Yogurt has the potential to cause fetal teratogenic in group D3

Pengaruh Pemberian Vanadil Sulfat dan Kromium (III) Klorida terhadap Fungsi Ginjal Mencit Putih Diabetes Dwisari Dillasamola; Surya Dharma; Helmi Arifin
Jurnal Sains Farmasi & Klinis Vol 1, No 1 (2014): J Sains Farm Klin 1(1), November 2014
Publisher : Fakultas Farmasi Universitas Andalas

The objective of this study was to identify the effect of two heavy metals, vanadyl sulphate and chromium (III) chloride on creatinine level of hyperglycemic mice induced by dexamethasone 11mg/kg. The experimental animals were grouped into five groups comprised of 5 white mice. Group I was used as control group, only received standard feeding and food supplement. Group II-V were induced with dexamethasone 11mg/kg to increase the blood glucose level. Group III was also given chromium (III) chloride 5.2 ug/20g. Group IV was also given vanadyl sulphate at the dose of 0.78 mg/20g. Group V received combination of vanadyl sulphate 0.39 mg/20g and chromium (III) chloride 2.6 ug/20g. The level of blood creatininewas determined by enzymatic method conducted for 42 days and observations were taken at day 7, 21 and 42. This study concluded that administration of vanadyl sulphate and chromium (III) chloride combination significantly reduced blood creatinine level of white mice (p<0,05).

Uji Aktivitas Antioksidan Ekstrak Etanol Daun Afrika Selatan (Vernonia amygdalina Del. )dengan Menggunakan Metode DPPH (1,1- diphenil-2-picryhidrazyl ) Dwisari Dillasamola; Mega Linda W
Jurnal Akademi Farmasi Prayoga Vol 1 No 1 (2016): Jurnal Akademi Farmasi Prayoga
Publisher : Jurnal Akademi Farmasi Prayoga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (258.847 KB)

Dilakukan penelitian tentang Uji Aktivitas Antioksidan Ekstrak Etanol Daun Afrika Selatan (Vernonia amygdalina Del) dengan menggunakan metode DPPH(1,1-diphenil-2-picryhidrazyl). Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan dari ekstrak etanol daun Afrika Selatan (Vernonia amygdalina Del)dengan pembanding vitamin C. Pengukuran aktivitas antioksidan dilakukan dengan menggunakan metode DPPH terhadap ekstrak etanol daun Afrika Selatan dengan konsentrasi (1000, 2000, 3000, 4000,5000)mcg/mL. Hasil penelitian menunjukkan ekstrak etanol daun Afrika Selatan (Vernonia amygdalina Del)mempunyai aktivitas antioksidan daun Afrika Selatan sangat lemah dengan IC50 3489,1759 mcg/mL terhadap radikal bebas DPPH.

Evaluation of Propolis and Milk Administration on Caffein-Induced Mus musculus Fetus Skeletal Dillasamola, Dwisari; A, Almahdy; Sari, Novita Purnama; Putri, Biomechy Oktomalio; Noverial, Noverial; Diliarosta, Skunda
Pharmaceutical Sciences and Research Vol. 5, No. 1
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Caffeine consumption by pregnant women at doses above 300 mg/day was suggested to cause skeletal damage. Propolis with high flavonoids concentration could increase the number of osteoblasts. This research aims to evaluate the effect of propolis and milk administration on fetal skeletal of caffeine-induced female mice (Mus musculus). Mice were divided into six groups: negative group, positive group of caffeine (a dose of 75 mg/kg BW), positive group of propolis (a dose of 1400 mg/kg BW), positive group of milk (200 ml), group D1 (caffeine 75 mg/kg BW and propolis 1400 mg/kg BW) and group D2 (caffeine 75 mg/kg BW and milk 200 ml). Data were processed using one-way ANOVA. The results showed that administration of propolis and milk on caffeine-induced mice during pregnancy does not affect the mice body weight, the number of fetuses and fetal weight significantly (P> 0.05). No skeletal defects detected in group D1 and D2 (observation with Alizarin solution) compared to the negative group. In conclusion, the admnistration of propolis at the dose of 1400 mg/kg BW and 200 ml of milk can repair skeletal damage caused by caffeine induction.

Bijak dalam Menggunakan Antibiotika di Nagari Padang Laweh Dwisari Dillasamola; Hansen Nasif; Yufri Aldi
Warta Pengabdian Andalas Vol 29 No 4 (2022)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jwa.29.4.382-387.2022

The high use of antibiotics inappropriately among the community today causes the problem of antibiotic resistance. Antibiotic resistance occurs when microorganisms have the ability to withstand the effects of an antibiotic drug. This can cause losses in terms of health, economy, and public health. To prevent the inappropriate use of antibiotics, education is carried out on how to use antibiotics wisely, which is good and right. The counseling method in this service activity is the lecture method where this method is good for targets with high and low education, especially the general public. The results that this service was that the community looks enthusiastic about carrying out this community service activity. The conclusion of this activity is that education and counseling can increase public knowledge about the use of antibiotics.

Penyuluhan dan Pelatihan Penggunaan Obat Tradisional serta Penerapan Hasil Penelitian Tumbuhan Sungkai (Peronema canescens Jack) kepada Masyarakat Dwisari Dillasamola; Yufri Aldi; Fatma Sri Wahyuni; Hansen Nasif; Yohannes Alen
Warta Pengabdian Andalas Vol 30 No 1 (2023)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jwa.30.1.60-66.2023

Indonesians, particularly those residing in rural areas with abundant plant diversity, have long relied on traditional medicine that utilizes plants. Sungkai (Peronema canescens Jack.) is one example of a widely-used traditional medicine known for its immunity-boosting properties. However, many people need more awareness of the potential benefits and risks of plants like Sungkai, so it is necessary to provide education and training to promote proper usage and ensure public safety. This community service activity aimed to equip individuals with the knowledge and skills to process plants accurately, utilize them appropriately based on the severity of the illness, and avoid any adverse side effects or toxicity. The counselling method used in this initiative involves lectures, which is effective for individuals with varying education levels, especially the general public. This program has yielded promising results, with the community displaying strong enthusiasm for the initiative. Ultimately, education and counselling services can significantly improve public understanding and use of traditional medicine.

Uji Efektifitas Ekstrak Etanol Daun Arbei (Rubus rosifolius Sm.) Terhadap Penurunan Kadar Glukosa Darah pada Mencit Diabetes Helmice Afriyeni; Rosiana Rizal; Armenia Armenia; Mike Esfika; Dwisari Dillasamola
Jurnal Sains Farmasi & Klinis Vol 10, No 2 (2023): J Sains Farm Klin 10(2), Agustus 2023
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.10.2.248-255.2023

Daun arbei (Rubus rosifolius Sm.) mengandung senyawa metabolit aktif seperti pomolic acid, tormentic acid, quercetin dan euscaphic acid yang berpotensi sebagai antihiperglikemia. Penelitian ini dilakukan untuk mengetahui pengaruh ekstrak etanol daun arbei (Rubus rosifolius Sm.) dan lama pemberian terhadap penurunan kadar glukosa darah mencit diabetes. Sebanyak 25 ekor mencit diinduksi dengan aloksan dosis 150 mg/kg secara intraperitonial. Pemeriksaan glukosa darah dilakukan dengan metode enzimatis menggunakan glukometer. Mencit dengan kadar glukosa darah sewaktu >200 mg/dL dibagi menjadi 5 kelompok yaitu kontrol positif (Na.CMC 0,5%), pembanding (glimepirid) dan kelompok ekstrak uji dosis 100, 200 dan 400 mg/kg. Perlakuan diberikan selama 15 hari dan pengukuran kadar glukosa darah dilakukan pada hari ke 5, 10 dan 15. Data hasil penelitian dianalisis menggunakan Anova Dua Arah dan dilanjutkan dengan uji Duncan post hoc pada tingkat kepercayaan 95%. Pemberian ekstrak uji berpengaruh signifikan (p<0.05) terhadap penurunan kadar glukosa darah mencit. Semua kelompok dosis ekstrak uji memberikan efek penurunan glukosa darah yang tidak berbeda signifikan (p>0.05) dengan kelompok yang diberi glimepiride. Efek penurunan kadar glukosa darah semakin besar seiring bertambah lama waktu pemberian ekstrak uji (p<0,05), nilai penurunan terbesar ditunjukkan pada hari ke 15. Hasil penelitian mengindikasikan ekstrak etanol daun arbei efektif menurunkan kadar glukosa darah dan nilai penurunannya sebanding dengan glimepirid.

EDUKASI PENGGUNAAN OBAT ANTIBIOTIK YANG BAIK DAN BENAR TERHADAP MASYARAKAT DI NAGARI SIPINANG PALEMBAYAN KABUPATEN AGAM Noverial Noverial; Yohannes Alen; Dwisari Dillasamola
BULETIN ILMIAH NAGARI MEMBANGUN Vol 6 No 4 (2023)
Publisher : LPPM (Institute for Research and Community Services) Universitas Andalas Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/bina.v7i4.556

Antibiotic resistance is a problem that arises in the community due to the high use of antibiotics inappropriately. The problem arises because of the lack of understanding of the community regarding the handling and use of antibiotic drugs. Microorganisms that have been resistant to antibiotics when given the same antibiotic, it cannot kill the microorganisms that are the target of this can cause antibiotic resistance. Therefore, the purpose of this activity is to provide knowledge and understanding to the community regarding the wise and good use of antibiotics to prevent drug resistance. This community education activity was carried out in nagari Sipinang, Palembayan District, Agam Regency, West Sumatra, with lecture education methods and open discussions with the community. Based on the results obtained, the community was very enthusiastic about this education and counseling activity and opened public knowledge related to antibiotic resistance. This community education activity was carried out in nagari Sipinang, Palembayan District, Agam Regency, West Sumatra, with lecture education methods and open discussions with the community. Based on the results obtained, the community was very enthusiastic about this education and counseling activity and opened public knowledge related to antibiotic resistance. This activity is expected to be a means for the community to use antibiotics wisely and well in the use of appropriate, accurate, and effective. In addition, this activity is also expected to provide the community with sufficient information to be wiser in obtaining and using antibiotics so that people are not afraid of antibiotic resistance if their use has been carried out properly and wisely. This activity is important because of the lack of information obtained by the community in Nagari Sipinang regarding the use of antibiotics so that this educational activity will also make people more concerned with health.

Co-Authors Aan Ardiansyah Abdullah Muhammad Faathir Adinny Julmiza Aditio Aditya Gufashar Afdal Afdal Afdal Afdal Afifah Hulwah Al-Khansaa, Syawwal Aldi, Yuffri Almahdy A Almahdy A Almahdy A Amirah Desri Andhini Aurellyta Ridwan Andini, Airiza Fitri Anjeli, Rada Ardiansyah, Aan Armenia, Armenia Armenia, Armenia Benardo Benardo Benardo, Benardo Biomechy Oktomalioputri, Biomechy Dehan Fahresta Desmawati Desmawati Dewi Rusnita Dian Ayu Juwita Elidahanum Husni Esfika, Mike Fahri, Idris Al Fashelia Azizaturrahmah Fatma Sri Wahyuni Fridhani Rahadiant Habib Shidiq Akbar Hana Syakira, Azya Hansen Nasif Helmi Arifin Helmice Afriyeni Helmice Afriyeni Iva Rama Fitria Julmiza, Adinny Larisa Aurellia Vilonia Lusi Octaviana Mega Linda W Mike Esfika Muhamad Aldo Putra Muhammad Abdul Najib Muhammad Aidi Satryo Muhammad Fazly Muhammad Rahil Dief Nadhira Yuri Maharani Nazar, Armenia Noverial Noverial Noverial Noverial Noverial, Noverial Novita Purnama Sari Novita Sari Nur Afrinin Syah Nur Afrinin Syah Putri, Biomechy Oktomalio Rachmaini, Fitri Rahmad Abdillah Rahmad Abdillah Rizal, Rosiana Rosiana Rizal Rusnita, Dewi Saniya De Nafisa Sari, Azzahra Ayu Sari, Novita Purnama Sayyida, Alya Siti Nurhajjah Skunda Diliarosta Srangenge, Yoneta Surya Dharma Suryati Suryati Syofyan Syofyan Syofyan Tofrizal Tofrizal Tofrizal Uce Lestari Vika Permata Gustam Widya Faizatul Zuhri Wira Sanjaya Yohannes Alen Yohannes Alen Yoneta Srangenge Yudistio Arnoza Yufri Aldi Zainini Arraysa Zozy Aneloi Noli

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