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Amanuddin Amanuddin
Laboratorium Penelitian dan Pengembangan Kefarmasian "Farmaka Tropis", Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology

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Sintesis 2’-Hidroksi-5’-Kloro-3,5-Dimetoksi-4-Hidroksikalkon Amanuddin Amanuddin; Hanggara Arifian; Agung Rahmadani; Rolan Rusli
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 11 (2020): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (331.825 KB) | DOI: 10.25026/mpc.v11i1.393

Abstract

Chalcone are compounds that have 2 aromatic rings connected by 3 carbon atoms which are an ?, ? unsaturated carbonyl system that have various biological activities. 2'-hydroxy-5'-chloro-3,5-dimethoxy-4-hydroxicalcone was synthesized from 2'-hydroxy-5'-chloro acetophenone and syringaldehyde using a NaOH catalyst. This compound was purified using Column Chromatography by isocratic method using n-hexane:ethyl acetate (15:1) as eluent. This compound has a Rf 0.75 and 2.7% of yield.
Co-Authors Hanggara Arifian Rahmadani, Agung Rolan Rusli