Fika Aryati
Laboratorium Penelitian dan Pengembangan Kefarmasian “Farmaka Tropis”, Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

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Isolasi dan Karakterisasi Kitin dari Limbah Cangkang Kerang Asia (Corbicula fluminea): Isolation and Characterization of Chitin from Asian Shell Waste (Corbicula fluminea) Ameilia Rachmadianty; Fika Aryati; Yurika Sastyarina
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 14 (2021): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (303.867 KB) | DOI: 10.25026/mpc.v14i1.543

Abstract

Chitin compounds are compounds that can be found from various animals of the Crustaceae group, for example such as crabs, shrimp, and shellfish. The purpose of this study was to find out the chitin content and chitin characteristics of asian shell waste (Corbicula fluminea). The stage of chitin insulation includes the process of deproteination using Sodium Hydroxide 3.5%, and the next process is the process of demineralization using Hydrochloric Acid 1 N. From the results of the isolation obtained chitin characterization in the form of chitin yield is 82.75%, with a grayish-white powder texture, and odorless, it perfectly soubled in Hydrochloric Acid 1 N, has a water content of 0.1764% and ash content of 58.0753%.
Pengaruh Pemberian Aromaterapi Pandan Wangi (Pandanus amaryllifolius) dan Lemon (Citrus limon L) dalam Menurunkan Tekanan Darah: The Effect of Aromatherapy Pandan Wangi (Pandanus amaryllifolius) and Lemon (Citrus limon L) in Lowering Blood Pressure Jihan Al-Mira; Adam M. Ramadhan; Fika Aryati
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 14 (2021): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (309.341 KB) | DOI: 10.25026/mpc.v14i1.560

Abstract

Fragrant pandan and lemon contain linalool compounds as much as 6% in fragrant pandan and as much as 20-50% are found in lemons, linalool compounds are very useful for stabilizing nerves so that they can have a calming effect. This study aims to determine the characteristics, description of the respondent's blood pressure before and after being given aromatherapy, and the effect of giving pandanus and lemon aromatherapy on the blood pressure of hypertension respondents who live in the Sempaja Timur Village. The research method used is a quasi-experimental method with a one group pretest and posttest design with a total of 20 respondents. The research procedure uses initial and final measurements. The results showed that the characteristics of the highest hypertension respondents were female as many as 15 respondents( 75%), 10 respondents aged 60 years (50%), work as a housewife as many as 13 respondents (65%), and the antihypertensive drug consumed was amlodipine as much as 20 respondents ( 100%). The results of this study found that there was an effect of giving aromatherapy pandanus and lemon on systolic blood pressure before being given aromatherapy with an average of 162.6 mmHg and after being given aromatherapy an average of 156.4 mmHg while diastolic blood pressure before giving aromatherapy was on average by 99.6 mmHg and after being given aromatherapy an average of 94.4 mmHg. The results of the descriptive study of giving fragrant pandan and lemon aromatherapy are in line with the results of statistical analysis using the Wilcoxon test method and the paired sample t-test with a p value (0,000) <0.05. hypertension significantly.
Uji Aktivitas Antibakteri Ekstrak Daun Gelinggang (Cassia alata L): Antibacterial Activity Test of Gelinggang Leaf Extracts (Cassia alata L) Khofifah Nur Oktavia; Fika Aryati; Herman Herman
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 14 (2021): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (292.831 KB) | DOI: 10.25026/mpc.v14i1.561

Abstract

Traditionally, gelinggang leaves are widely used for treatment of various skin diseases. The potential of gelinggang leaves as a medicinal plant is expected due to the presence of secondary metabolite compounds that have activities, one of which can inhibit the growth of fungi and bacteria. This study aims to determine the antibacterial activity of gelinggang leaf extract against Staphylococcus aureus and Escherichia coli bacteria. The study began with extraction process of gelinggang leaves, phytochemical screening tests and testing of antibacterial activity from gelinggang leaf extracts carried out by the agar diffusion method using a well. Gelinggang leaf samples were macerated with 96% ethanol solvent and then tested for antibacterial activity in concentrations of 5%, 10%, and 15%. The results of the phytochemical screening test indicated that the gelinggang leaf extract was positive for flavonoids, saponins, phenolics, and terpenoids. On antibacterial activity test of the ethanolic extract of gelinggang leaves, it revealed that there was an inhibition activity for both Staphylococcus aureus and Escherichia coli bacteria with the best activity at a concentration of 15%.
Isolasi Fungi Endofit Daun Kopi Robusta (Coffea canephora): Isolation of Endophytic Fungus Robusta Coffee Leaf (Coffea canephora) Nilam Ratna Rizkyanti; Herman Herman; Fika Aryati
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 14 (2021): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (447.875 KB) | DOI: 10.25026/mpc.v14i1.569

Abstract

Endophytic fungi are organisms that live in plant tissues that have the potential to produce the same secondary metabolites as their host. This study attempted to isolate and also characterize endophytic fungi from Robusta coffee leaves (Coffea canephora). Data collection was carried out in several stages, namely isolation of endophytic fungi by surface sterilization method, and conventional characterization of endophytic fungi by observing the morphology of endophytic fungi. The results showed that as many as 4 isolates of endophytic fungi were isolated from Robusta coffee leaves (Coffea canephora) with macroscopic characteristics of white color with orange circle edges, cotton-like shape, and green and orange spots on the underside of the fungus.
Isolasi dan Karakterisasi Kitosan dari Limbah Cangkang Kerang Asia (Corbicula fluminea): Isolation and Characterization of Kitosan from Asian Shell Waste (Corbicula fluminea) Rizki Noor Amelia; Fika Aryati; Yurika Sastyarina
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 14 (2021): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (277.508 KB) | DOI: 10.25026/mpc.v14i1.583

Abstract

Chitosan is a substance contained in shellfish that is the most biopolymer after cellulose. The study aims to determine the best yield of chitosan results of Asian shell isolation (Corbicula fluminea) based on variations in Sodium hydroxide concentration and length of deacetylation process, and to find the characteristics of chitosan isolation results based on International Standards. The process of chitosan isolation goes through several stages, namely deproteination using a solution of Sodium hydroxide 3,5% at a temperature of 65°C for 2 hours, demineralization using a solution of Hydrochloric acid 1N at a temperature of 65°C for 2 hours, and the stage of deacetylation that is optimized with variations in Sodium hydroxide concentration of 40%, 50%, and 60% and variations in the length of stirring time of 30, 60, and 90 minutes. The results showed the best chitosan yield of 90,1% obtained from the deacetylation process using a Sodium hydroxide concentration of 60% with a stirring time of 60 minutes. The resulting chitosan characteristics are white powder, odorless, soluble in 2% acetic acid, and has a water content of 0%.
Formulasi Lilin Aromaterapi Berbahan Aktif Minyak Atsiri Sereh Wangi (Cymbopogon winterianus) dan Jeruk Lemon (Citrus limon): Aromatherapy Candle Formulation with Active Ingredients of Citronella (Cymbopogon winterianus) and Lemon (Citrus limon) Essential Oils Vika Aura Rislianti; Laode Rijai; Fika Aryati
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 14 (2021): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (311.385 KB) | DOI: 10.25026/mpc.v14i1.591

Abstract

Aromatherapy is therapy that uses aromatic compounds to treat, cut or prevent disease, infection, and anxiety by inhaling them. Citronella (Cymbopogon winterianus) and lemon (Citrus limon) have essential oils that work as aromatherapy. The aim of the study was to get aromatherapy candle preparations from essential oils of citronella and lemon. The research was carried out experimentally by making aromatherapy wax preparations from the formulation of stearic acid and paraffin wax with a ratio of 30%: 70% (F1), 40%: 60% (F2) , 50%: 50% (F3), 60%: 40% (F4), 70%: 30% (F5) and adding a combination of citronella essential oil and lemon essential oil in a ratio of 1%: 5% (A1), 2%: 4% (A2), 3%: 3% (A3), 4%: 2% (A4), 5%: 1% (A5), tests of physical stability were performed as burn time and melting point and determination of panellist’s preferences in the form of visual preference, candle aroma before combustion, candle aroma after combustion, detection of candle odor for the first time and perceived therapeutic effect. The best wax base is 60%: 40% (F4) and the best aromatherapy wax formulation is a combination of citronella essential oil and lemon essential oil 4%: 2% (A4) and 5% : 1% (A5) to produce a comfortable and pleasant therapeutic effect.