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All Journal Jurnal Teras Kesehatan Jurnal Inovasi Farmasi Indonesia Jurnal Pharma Bhakta Strada Journal of Pharmacy
Krisogonus Ephrino Seran
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Chemistry Decision Sciences, Operations Research & Management Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Physics Public Health

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EVALUASI WAKTU PEMBERIAN AMLODIPIN TERHADAP PENURUNAN TEKANAN DARAH PASIEN HIPERTENSI DI PUSKESMAS X KOTA KEDIRI Wika Admaja; Yogi Bhakti Marhenta; Krisogonus Ephrino Seran; Iyana Milati Azka Wijanarko
Jurnal Inovasi Farmasi Indonesia (JAFI) Vol 2, No 1 (2020): Vol. 2 No. 1 Desember 2020
Publisher : Universitas Kadiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30737/jafi.v2i1.1286

Abstract

Tekanan darah manusia berjalan mengikuti ritme sirkadian, yaitu tekanan darah  turun pada saat tidur dan meningkat pada pagi hari hal ini terjadi pada sebagian besar individu. Berbagai macam parameter kardiovaskular, termasuk detak jantung, tekanan darah, dan resistensi perifer, diketahui bervariasi sepanjang hari. Beberapa kejadian jantung dan otak telah lama dilaporkan tertinggi terjadi di pagi hari. Efektivitas calcium channel blockers (CCBs) menurut waktu pemberian masih belum jelas. Tujuan pada penelitian ini adalah untuk mengeahui pengaruh penurunan tekanan darah pasien hipertensi pada pemberian amlodipin 5 mg di pagi hari dibandingkan malam hari.  Metode penelitian yang digunakan yaitu analisis observasional secara prospektif berdasarkan data rekam medik pasien hipertensi tunggal dengan jumlah sampel 66 pasien (kelompok penggunaan amlodipin pagi 33 pasien dan amlodipin malam 33 pasien). Diperoleh hasil penurunan sistole sebesar -7,27 dan diastole -3,33 pada kelompok amlodipin yang diminum pagi hari. Penurunan sistole pada pemberian amlodipin malam hari sebesar -15,76 dan diastole sebesar -8,48. Hasil uji Mann Whitney diketahui nilai p = 0,036 (<0,05) pada tekanan sistole pagi dan malam, nilai  p = 0,044 (<0,05) pada tekanan diastole pagi dan malam. Diperoleh kesimpulan terdapat pengaruh pemberian amlodipine pagi dan malam pada tekanan sistole dan diastole . Pemberian amlodipine 5 mg pada malam hari lebih menurunkan tekanan darah sistole dan diastole dibandingkan pemberian pada pagi hari. 
RASIONALITAS PENGGUNAAN OBAT ANTIBIOTIK PADA PAS IEN BALITA PENDERITA DIARE DI RUMAH SAKIT AURA SYI FA KABUPATEN KEDIRI TAHUN 2 0 2 1 Yogi Bhakti Marhenta; Krisogonus Ephrino Seran; Wika Admaja
JURNAL PHARMA BHAKTA Vol 3 No 1 (2023): Mei 2023
Publisher : FAKULTAS FARMASI, INSTITUT ILMU KESEHATAN BHAKTI WIYATA

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Abstract

Latar belakang: Penyakit diare sampai saat ini masih menjadi masalah kesehatan masyarakat seperti negara berkembang seperti Indonesia karena morbiditas dan mortalitasnya masih tinggi. Tujuan: Penelitian ini bertujuan untuk mengetahui rasionalitas penggunaan obat antibiotik pada pasien anak penderita diare. Penggunaan obat antibiotik yang paling banyak digunakan pada infeksi yang disebabkan oleh bakteri, Kerasional antibiotik tersebut meliputi tepat indikasi, tepat dosis, tepat lama pemberian, dan tepat cara pemberian. Metode: Penelitian ini diperoleh dari rekam medik menggunakan metode retrospektif yang menjalani rawat inap pada tahun 2021. Kriteria inklusi adalah pasien anak penderita diare yang di rawat inap mendapat terapi antibiotik di Instalasi Rawat Inap Rumah Sakit Aura Syifa Kabupaten Kediri Hasil: penelitian menunjukkan hasil penggunaan obat antibiotik yang diberikan pada pasien anak diare di Instalasi Rawat Inap Rumah Sakit Aura Syifa Kabupaten Kediri pada Periode 2021 adalah Metronidazole sebesar 44%, Ceftriaxone sebesar 44%, Cefotaxime sebesar 6%, dan juga Kombinasi obat Antibiotik Metronidazole + Ceftriaxone sebesar 6%. Kerasionalitas penggunaan Obat Antibiotik pasien anak penderita diare bisa dikatakan Rasional meliputi Tepat Indikasi sebesar 100%, Tepat Dosis sebesar 100%, Tepat Cara Pemberian 100%, Tepat Lama Pemberian sebesar 82%. Simpulan: dari hasil penelitian penggunaan obat antibiotik pada pasien balita diare di rumah sakit aura syifa dikatakan rasional.
Rationality of Use of Antibiotic at North Region City Primary Health Care Centre in Kediri City Hanie Kusuma Wardani; Krisogonus Ephrino Seran; Yogi Bhakti Marhenta; Febriarmayenri
Strada Journal of Pharmacy Vol. 4 No. 2 (2022): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v4i2.68

Abstract

The implementation of health services by ensuring safety, effectiveness, and affordable costs for people who receive treatment is one of the efforts carried out by the Rational Drug Use program. It is said that the use of drugs is rational if the patient gets treatment according to clinical needs, the dose is as needed, the drug can be used for a sufficient period of time and at an affordable cost. This study aims to determine the rationality of the use of antibiotic drugs at North Region City Primary Health Care Centre in Kediri City with the indicators of Right Indication, Right Patient, Right Drug, Right Dosage, and Beware of Drug Side Effects. This study is a descriptive study with retrospective data collection by looking at prescriptions and medical records of patients using antibiotics and supported by open interviews with pharmacists. Based on the results of the study showed that the use of antibiotics in 273 samples obtained Penicillin class antibiotics was 46.89%, Other Antibiotics of 26.01%, Antituberculosis of 8.42%, Quinolones at 11.72%, Aminoglycosides of 5.13%, Tetracyclines of 1.10%, and Macrolides of 0.73%. The percentage of rationality for the use of antibiotic drugs which includes indicators of Right Indication, Right Patient, Right Drug, Right Dosage, and Alert for Drug Side Effects is 96%.
Rationality of Use of Analgetic-Antipyretic Medicines in Northern Region Primary Health Centre of Kediri City Hanie Kusuma Wardani; Krisogonus Ephrino Seran; Elisa Nur Farida
Strada Journal of Pharmacy Vol. 2 No. 1 (2020): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v2i1.133

Abstract

One of the efforts carried out by the national rational drug use program is health services that ensure safety, effectiveness, and affordable costs for people who receive or receive treatment. It is said that the use of drugs is rational if the patient gets treatment according to clinical needs, the dose is as needed, the drug can be used for a sufficient period of time and at affordable costs. This study aims to determine the rationality of the use of analgesic-antipyretic drugs in the Northern Region Primary Health Centre of Kediri City which includes: right indication, right patient, right drug, right dose, and alert for drug side effects. This study is a descriptive study conducted by retrospective observation and data collection by looking at prescriptions and medical record data supported by interviews with pharmacists. Based on the results of the research in the Northern Region Primary Health Centre of Kediri City, it can be found that the use of analgesic-antipyretic drugs in 304 samples was obtained paracetamol 33.88%, paracetamol liquid 18.42%, Alpara 10.20%, ibuprofen 12.17%, acid mefenamic 8.88%, diclofenac sodium 7.24%, piroxicam 4.93%, and aspirin 4.28%. The percentage of rationality of using analgesic-antipyretic drugs in the Northern Region Primary Health Centre of Kediri City, got the results, namely: right indication, right patient, right drug, right dose, and alert for drug side effects by 100%.
Perilaku Pasien Dalam Penggunaan Obat Antihipertensi Menggunakan HealthBelief  Model Di Puskesmas PuhjarakKabupaten KediriPerilaku Pasien Dalam Penggunaan Obat Antihipertensi Menggunakan HealthBelief  Model Di Puskesmas PuhjarakKabupaten Kediri Krisogonus Ephrino Seran
JURNAL TERAS KESEHATAN Vol 8 No 2 (2025): Jurnal Teras Kesehatan
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Politeknik Al Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.38215/vrpvwz69

Abstract

Compliance of hypertension sufferers in using antihypertensive drugs can control blood pressure and reduce the risk of long-term organ damage. Health Belief Model is one of the most widely used conceptual models and frameworks in behavioral research and health promotion. This model can reduce the risk of severity as a result of complications from a disease through behavioral changes which are one of the indicators of successful treatment implementation. The purpose of this study was to determine whether there was an influence of patient behavior on the use of antihypertensive drugs at the Puhjarak Health Center, Kediri Regency. The research method is analytical observational with a cross-sectional approach, the number of samples used was 93 respondents, data collection was carried out using a questionnaire , data analysis using multiple linear regression tests. The results have been found, namely with a p value of 0.000 <0.05, which means that there is an influence between the independent variable (perceived susceptibility, perceived severity, perceived benefit, perceived barrier, self-efficacy and cues to action) on the dependent variable (behavior of hypertensive patients in using antihypertensive drugs) and the R Square value (determination coefficient) is 0.526, 
Co-Authors Elisa Nur Farida Febriarmayenri Hanie Kusuma Wardani Iyana Milati Azka Wijanarko Wika Admaja Wika Admaja Yogi Bhakti Marhenta Yogi Bhakti Marhenta