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All Journal E-Jurnal Medika Udayana ISM (Intisari Sains Medis) : Jurnal Kedokteran Cardiovascular and Cardiometabolic Journal (CCJ) Aesculapius Medical Journal
I Gede Bagus Gita Pranata Putra
Universitas Warmadewa
Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Hubungan antara terapi statin dengan kadar gula darah puasa dan profil lipid pada pasien coronary artery disease di RSUD Sanjiwani I Gusti Ayu Inten Heny Pratiwi; Ketut Erna Bagiari; I Gede Bagus Gita Pranata Putra
Intisari Sains Medis Vol. 12 No. 1 (2021): (Available online : 1 April 2021)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (321.926 KB) | DOI: 10.15562/ism.v12i1.953

Abstract

Background: Statin therapy has an important role to coronary artery disease (CAD) which can lowered cholesterol levels and give pleiotropic effects to inhibit inflammatory reactions. Statin have some side effects and new onset diabetes is one of them, where diabetes is also a risk factor for CAD. This study aims to know the correlation of statin therapy and fasting blood glucose levels of CAD patient in Sanjiwani Hospital.Methods: The design of this study was analytic cross-sectional study that started from November 17th 2020 until January 31st 2021 in Sanjiwani Hospital. A total of 68 patients were included in this study. The data source of this study was secondary data from patient’s medical record. The inclusion criteria was all CAD patients with statin therapy who had history of fasting blood glucose test that visited cardiology department of Sanjiwani Hospital at year 2020. Normality test, bivariate, and multivariate analysis was done in this study.Results: Bivariate analysis using Spearman showed a weak positive correlation between duration of statin therapy with fasting blood glucose levels (r=0,353; p= 0,003), and Kruskal Wallis analysis showed no correlation between statin type with fasting blood glucose levels.Conclusion: Duration of statin therapy has a weak correlation with fasting blood glucose levels so that statin still can be given with concerns to its benefit of reduced mortality. Prevention of new onset diabetes should be done by lifestyle modification and periodic blood glucose monitoring.  Latar Belakang: Terapi statin memiliki peranan penting terhadap coronary artery disease (CAD) yang mampu menurunkan kadar kolesterol serta memberikan efek pleiotropik untuk menghambat reaksi inflamasi. Statin memiliki beberapa efek samping, salah satunya adalah risiko diabetes onset baru dimana diabetes merupakan salah satu faktor risiko CAD. Penelitian ini dilakukan untuk mengetahui hubungan antara terapi statin dengan kadar gula darah puasa pasien CAD di RSUD Sanjiwani.Metode: Desain penelitian yang digunakan adalah analitik cross-sectional yang dilakukan dari 17 November 2020 sampai 31 Januari 2021 di RSUD Sanjiwani. Sebanyak 68 pasien diikutkan dalam penelitian ini. Sumber data pada penelitian ini berupa data sekunder yang didapatkan dari rekam medis pasien dengan kriteria inklusi yaitu semua pasien CAD dengan terapi statin dan memiliki riwayat pemeriksaan kadar gula darah puasa yang melakukan kontrol di poli jantung RSUD Sanjiwani tahun 2020. Uji normalitas, analisis bivariat, dan multivariat dilakukan pada penelitian ini.Hasil: Analisis bivariat dengan Spearman menunjukan adanya korelasi positif lemah antara durasi terapi statin dengan kadar gula darah puasa (r=0,353; p= 0,003), sedangkan hasil analisis Kruskall Wallis menunjukan tidak ada korelasi antara jenis statin dengan kadar gula darah puasa.Simpulan: Durasi terapi statin memiliki hubungan lemah dengan kadar gula darah puasa sehingga terapi statin masih dapat diberikan dengan memperhatikan keuntungan terapi yang lebih besar. Pencegahan terhadap risiko diabetes onset baru tetap dilakukan dengan modifikasi gaya hidup serta pemantauan gula darah berkala.
Prevalence and Impact of Modifiable Risk Factors on Acute Coronary Syndrome: A Case Control Study Anak Agung Ngurah Anindya Kusuma; I Gede Bagus Gita Pranata Putra
Cardiovascular and Cardiometabolic Journal (CCJ) Vol. 5 No. 1 (2024): Cardiovascular and Cardiometabolic Journal
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ccj.v5i1.2024.23-34

Abstract

Highlights: 1. Smoking duration, dyslipidemia, hypertension, diabetes mellitus, obesity, and hyperuricemia, are significantly associated with ACS. 2. Obesity and hypertension are identified as risk factors for inpatient ACS. - Background: Acute coronary syndrome (ACS) is defined by the abrupt reduction or total obstruction of blood flow to the myocardium. Recognized risk factors for ACS include conditions such as hypertension, dyslipidemia, smoking, obesity, diabetes mellitus, hyperuricemia, as well as variables like age, gender, and family history of the ailment. The objective of this research was to examine the prevalence and importance of modifiable risk factors associated with ACS. Material and Methods: The study is structured as a prospective case-control study. The research sample comprises 100 ACS patients, categorized into three groups: STEMI, NSTEMI, and UAP. The Chi-Square test and logistic regression were used to examine the samples. The threshold for statistical significance was set at p<0.05. Results: ACS occurred more frequently in male patients (54%) and those aged ≥ 40 years (85%). Several factors demonstrated significant associations with ACS, including smoking habits, dyslipidemia, hypertension, diabetes mellitus, obesity, and hyperuricemia. Among these, inpatient ACS was notably linked with obesity (OR: 7.42; 95% CI: 1.48-37.11; p=0.015) and hypertension (OR: 0.13; 95% CI: 0.03-0.53; p=0.005). The presence of ACS was also correlated with a notable increase in inpatient care, with obesity and hypertension emerging as risk factors for inpatient ACS. Conclusion:  ACS was more common in males and individuals aged 40 or older, with significant associations identified between ACS and various factors, including smoking, dyslipidemia, diabetes, obesity, hyperuricemia, and hypertension, with obesity and hypertension specifically linked to inpatient ACS.
HUBUNGAN ANTARA HIPERURISEMIA DENGAN HIPERTENSI DI RSUD SANJIWANI GIANYAR TAHUN 2019 Sarilan, I Putu; Putra, IGB Gita Pranata; Cahyawati, Putu Nita
E-Jurnal Medika Udayana Vol 13 No 1 (2024): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2024.V13.i01.P11

Abstract

Latar Belakang: Hipertensi masih menjadi penyebab utama penyakit kardiovaskular dan kematian di dunia, termasuk di Indonesia. Berdasarkan pada penelitian sebelumnya ditemukan adanya kontroversi terkait hubungan antara hiperurisemia dan hipertensi. Tujuan: Penelitian ini bertujuan untuk mengetahui hubungan antara hiperurisemia dengan kejadian hipertensi tersebut. Metode: Penelitian ini dilakukan di RSUD Sanjiwani Gianyar dengan desain penelitian observasional analitik cross-sectional. Data diambil dari rekam medis pasien pada periode Januari–Desember 2019. Teknik pengambilan sampel menggunakan purpossive sampling dengan jumlah sampel sebanyak 104. Hasil: Karakteristik sampel pada penelitian ini yaitu mayoritas berusia lebih dari 60 tahun (51%) dan didominasi oleh jenis kelamin laki-laki (57.7%). Kejadian hiperurisemi pada pasien hipertensi adalah 68.3%. Kejadian hiperurisemia lebih banyak terjadi pada pasien hipertensi grade 1 (68.8%) dibandingkan dengan hipertensi grade 2 (67.2%). Hasil analisis menggunakan uji korelasi Spearman. menemukan bahwa nilai p>0.05, r -0.010. Kesimpulan: Hasil yang menunjukan bahwa tidak terdapat hubungan signifikan antara hiperurisemia dan hipertensi di RSUD Sanjiwani Gianyar tahun 2019. Kata kunci : Hipertensi, Hiperurisemia, RSUD Sanjiwani Gianyar
Hubungan Aktivitas Fisik dan Daya Tahan Kardiovaskular Pada Mahasiswa Laki-Laki Tim Bantuan Medis Baswara Prada Angkatan 2018 dan 2019 Made Billy Dwiki Saputra; IGB Gita Pranata Putra; Desak Putu Citra Udiyani
Aesculapius Medical Journal Vol 2 No 1 (2022): Juni
Publisher : Fakultas Ilmu Kedokteran dan Ilmu Kesehatan, Universitas Warmadewa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/amj.2.1.2022.57-62

Abstract

[Relationship Physical Activity and Cardiovascular Endurance In Male Students of 2018 and 2019 Baswara Prada Medical Assistance Team] Physical activity is a process of body movement created by muscles and utilizing energy. The prevalence of a minimal physical activity, the higher the number caused by the busyness of the students. This affects one of the building blocks of physical fitness, namely cardiovascular endurance. The aim of the study was to determine the correlation between physical activity and cardiovascular endurance in male students of the 2018 and 2019 Baswara Prada Medical Assistance Team. This study applied an observational study, and cross sectional design which included 51 male students of the 2018 and 2019 Baswara Prada medical assistance team. Data were collected by taking secondary Harvard step test data to measure cardiovascular endurance and primary data by fill the GPAQ survey to determine activity. physical. Data analysis used SPSS and level of significant is 0.05. As per results of Chi-square analysis, there was a significant correlation between the relationship between physical activity and cardiovascular endurance (p=0.000) in male students of the 2018 and 2019 Baswara Prada Medical Assistance Team.
Hubungan Kadar Asam Urat Terhadap Kejadian Sindrom Koroner Akut di RSUD Sanjiwani Gianyar Tahun 2018-2019 I Gusti Lanang Agung Wiradinata; I Gede Bagus Gita Pranata Putra; Luh Gde Evayanti
Aesculapius Medical Journal Vol 2 No 1 (2022): Juni
Publisher : Fakultas Ilmu Kedokteran dan Ilmu Kesehatan, Universitas Warmadewa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/amj.2.1.2022.21-25

Abstract

Sindrom Koroner Akut (SKA) merupakan manifestasi klinis dari Penyakit Jantung Koroner dengan spektrum NonST Elevation Miocard Infark (NSTEMI), ST Elevation Miocard Infark (STEMI) dan Unstable Angina Pectoris (UAP). Salah satu faktor predisposisi yang memicu disfungsi endotel pada SKA yaitu hiperurisemia. Penelitian ini bertujuan untuk mengetahui hubungan kadar asam urat dengan kejadian SKA di RSUD Sanjiwani. Penelitian ini menggunakan desain analitik dengan pendekatan cross-sectional. Data diambil dari rekam medis pasien diagnosis SKA tahun 2018-2019. Sebanyak 69 sampel diperoleh dengan metode purposive sampling berdasarkan kriteria inklusi dan eksklusi. Kedua variable di uji menggunakan pearson chi-square (p < 0,05) dengan Statistical Package for Social Science (SPSS) versi 23. Berdasarkan analisis didapatkan bahwa kadar asam urat tidak berhubungan dengan kejadian SKA pada pasien rawat inap di RSUD Sanjiwani pada tahun 2018-2019 (p = 0,717). Asam urat dapat berperan sebagai cardioprotector melalui mekanisme penghambatan stress oksidatif.
Gambaran Kualitas Tidur Penderita Hipertensi di Puskesmas II Denpasar Barat Bunganing Eswarya; I Gede Bagus Gita Pranata Putra; I Ketut Tangking Widarsa
Aesculapius Medical Journal Vol 3 No 2 (2023): June
Publisher : Fakultas Ilmu Kedokteran dan Ilmu Kesehatan, Universitas Warmadewa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/amj.3.2.2023.240-246

Abstract

Hypertension is a condition in which the blood pressure is above 140/90 mmHg. Hypertension could be prevented by controlling the sleep quality. Until now there has not been any studies to clearly depict sleep quality. This study aims to understand the description of sleep quality as well as its characteristic in Puskesmas II Denpasar Barat hypertension subjects. Observational descriptive study was used using cross sectional method and consecutive sampling. The study conducted at Puskesmas II Denpasar Barat with 96 total samples. Pittsburg Sleep Quality Index (PSQI) questionnaire was used to assess the quality of sleeps. Data gained from the questionnaire was analyzed bivariately and univariately. The results shows that more than a half (64%) hypertension patients are having a poor sleep quality with long sleep latency as the component with the highest proportion (57,3%). Poor sleep qualities are more frequent in patients within the age range of 18-39 years rather than older patients. This study also finds that higher hypertension grade appears more often as the sleep quality gets worse. With this study, hopefully Puskesmas II Denpasar Barat could emphasize the importance of sleep quality as a preventive act towards fighting hypertension. Keywords: Hypertension, Quality of Sleep
Hubungan antara Kadar Asam Urat dengan Profil Lipid pada Pasien Sindrom Koroner Akut di RSUD Sanjiwani Gianyar I Gusti Ngurah Bayu Paramartha; I Gede Bagus Gita Pranata Putra; Sri Ratna Dewi
Aesculapius Medical Journal Vol 3 No 3 (2023): October
Publisher : Fakultas Ilmu Kedokteran dan Ilmu Kesehatan, Universitas Warmadewa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/amj.3.3.2023.284-291

Abstract

AbstractThe Correlation Between Uric Acid and Lipid Profile in Acute Coronary Syndrome Patient of Sanjiwani Hospital GianyarSeveral studies show that high uric acid levels is linking to the incidence of acute coronary syndromes and dyslipidemia that leads to heart disease. The aim of this study is to determine the association between uric acid and lipid profile in acute coronary syndrome patients of Sanjiwani Hospital Gianyar. Cross-sectional analysis is the type of data analysis that is being used in this study and was conducted at the Sanjiwani Hospital, Gianyar, with a total of 45 subjects involved. Spearman correlation test showed that there was a significant positive correlation between uric acid levels and Total Cholesterol (TC) (r = 0.467 and p = 0.001). There was a significant positive correlation between uric acid levels and Low Density Lipoprotein (LDL) (r= 0.348 and p value = 0.019). There was a significant negative correlation between uric acid levels and High Density Lipoprotein (HDL) (r= -0.445 and p = 0.002). There was no significant correlation between uric acid levels and Triglycerides (TG) (r = 0.232 and p = 0.124). It was also found that more than 50% of subjects had uric acid levels in the high category (53.3%), optimal Total Cholesterol (TC) levels (80%), normal High Density Lipoprotein (HDL) levels (57.8%), and optimal Triglycerides (TG) levels (71.1%). Meanwhile, 46.7% of subjects had optimal Low Density Lipoprotein (LDL) levels.
Co-Authors Anak Agung Ngurah Anindya Kusuma Bunganing Eswarya Bunganing Eswarya Cahyawati, Putu Nita Desak Putu Citra Udiyani I Gusti Ayu Inten Heny Pratiwi I Gusti Lanang Agung Wiradinata I Gusti Ngurah Bayu Paramartha I Gusti Ngurah Bayu Paramartha K Tangking Widarsa Ketut Erna Bagiari Luh Gde Evayanti Made Billy Dwiki Saputra Sarilan, I Putu Sri Ratna Dewi