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Hubungan Kadar Asam Urat Terhadap Kejadian Sindrom Koroner Akut di RSUD Sanjiwani Gianyar Tahun 2018-2019 I Gusti Lanang Agung Wiradinata; I Gede Bagus Gita Pranata Putra; Luh Gde Evayanti
AMJ (Aesculapius Medical Journal) Vol. 2 No. 1 (2022): June
Publisher : Fakultas Ilmu Kedokteran dan Ilmu Kesehatan, Universitas Warmadewa

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Abstract

Sindrom Koroner Akut (SKA) merupakan manifestasi klinis dari Penyakit Jantung Koroner dengan spektrum NonST Elevation Miocard Infark (NSTEMI), ST Elevation Miocard Infark (STEMI) dan Unstable Angina Pectoris (UAP). Salah satu faktor predisposisi yang memicu disfungsi endotel pada SKA yaitu hiperurisemia. Penelitian ini bertujuan untuk mengetahui hubungan kadar asam urat dengan kejadian SKA di RSUD Sanjiwani. Penelitian ini menggunakan desain analitik dengan pendekatan cross-sectional. Data diambil dari rekam medis pasien diagnosis SKA tahun 2018-2019. Sebanyak 69 sampel diperoleh dengan metode purposive sampling berdasarkan kriteria inklusi dan eksklusi. Kedua variable di uji menggunakan pearson chi-square (p < 0,05) dengan Statistical Package for Social Science (SPSS) versi 23. Berdasarkan analisis didapatkan bahwa kadar asam urat tidak berhubungan dengan kejadian SKA pada pasien rawat inap di RSUD Sanjiwani pada tahun 2018-2019 (p = 0,717). Asam urat dapat berperan sebagai cardioprotector melalui mekanisme penghambatan stress oksidatif.
Hubungan antara terapi statin dengan kadar gula darah puasa dan profil lipid pada pasien coronary artery disease di RSUD Sanjiwani I Gusti Ayu Inten Heny Pratiwi; Ketut Erna Bagiari; I Gede Bagus Gita Pranata Putra
Intisari Sains Medis Vol. 12 No. 1 (2021): (Available online : 1 April 2021)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (321.926 KB) | DOI: 10.15562/ism.v12i1.953

Abstract

Background: Statin therapy has an important role to coronary artery disease (CAD) which can lowered cholesterol levels and give pleiotropic effects to inhibit inflammatory reactions. Statin have some side effects and new onset diabetes is one of them, where diabetes is also a risk factor for CAD. This study aims to know the correlation of statin therapy and fasting blood glucose levels of CAD patient in Sanjiwani Hospital.Methods: The design of this study was analytic cross-sectional study that started from November 17th 2020 until January 31st 2021 in Sanjiwani Hospital. A total of 68 patients were included in this study. The data source of this study was secondary data from patient’s medical record. The inclusion criteria was all CAD patients with statin therapy who had history of fasting blood glucose test that visited cardiology department of Sanjiwani Hospital at year 2020. Normality test, bivariate, and multivariate analysis was done in this study.Results: Bivariate analysis using Spearman showed a weak positive correlation between duration of statin therapy with fasting blood glucose levels (r=0,353; p= 0,003), and Kruskal Wallis analysis showed no correlation between statin type with fasting blood glucose levels.Conclusion: Duration of statin therapy has a weak correlation with fasting blood glucose levels so that statin still can be given with concerns to its benefit of reduced mortality. Prevention of new onset diabetes should be done by lifestyle modification and periodic blood glucose monitoring.  Latar Belakang: Terapi statin memiliki peranan penting terhadap coronary artery disease (CAD) yang mampu menurunkan kadar kolesterol serta memberikan efek pleiotropik untuk menghambat reaksi inflamasi. Statin memiliki beberapa efek samping, salah satunya adalah risiko diabetes onset baru dimana diabetes merupakan salah satu faktor risiko CAD. Penelitian ini dilakukan untuk mengetahui hubungan antara terapi statin dengan kadar gula darah puasa pasien CAD di RSUD Sanjiwani.Metode: Desain penelitian yang digunakan adalah analitik cross-sectional yang dilakukan dari 17 November 2020 sampai 31 Januari 2021 di RSUD Sanjiwani. Sebanyak 68 pasien diikutkan dalam penelitian ini. Sumber data pada penelitian ini berupa data sekunder yang didapatkan dari rekam medis pasien dengan kriteria inklusi yaitu semua pasien CAD dengan terapi statin dan memiliki riwayat pemeriksaan kadar gula darah puasa yang melakukan kontrol di poli jantung RSUD Sanjiwani tahun 2020. Uji normalitas, analisis bivariat, dan multivariat dilakukan pada penelitian ini.Hasil: Analisis bivariat dengan Spearman menunjukan adanya korelasi positif lemah antara durasi terapi statin dengan kadar gula darah puasa (r=0,353; p= 0,003), sedangkan hasil analisis Kruskall Wallis menunjukan tidak ada korelasi antara jenis statin dengan kadar gula darah puasa.Simpulan: Durasi terapi statin memiliki hubungan lemah dengan kadar gula darah puasa sehingga terapi statin masih dapat diberikan dengan memperhatikan keuntungan terapi yang lebih besar. Pencegahan terhadap risiko diabetes onset baru tetap dilakukan dengan modifikasi gaya hidup serta pemantauan gula darah berkala.
Gambaran Kualitas Tidur Penderita Hipertensi di Puskesmas II Denpasar Barat Bunganing Eswarya; I Gede Bagus Gita Pranata Putra; I Ketut Tangking Widarsa
AMJ (Aesculapius Medical Journal) Vol. 3 No. 2 (2023): June
Publisher : Fakultas Ilmu Kedokteran dan Ilmu Kesehatan, Universitas Warmadewa

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Abstract

Hypertension is a condition in which the blood pressure is above 140/90 mmHg. Hypertension could be prevented by controlling the sleep quality. Until now there has not been any studies to clearly depict sleep quality. This study aims to understand the description of sleep quality as well as its characteristic in Puskesmas II Denpasar Barat hypertension subjects. Observational descriptive study was used using cross sectional method and consecutive sampling. The study conducted at Puskesmas II Denpasar Barat with 96 total samples. Pittsburg Sleep Quality Index (PSQI) questionnaire was used to assess the quality of sleeps. Data gained from the questionnaire was analyzed bivariately and univariately. The results shows that more than a half (64%) hypertension patients are having a poor sleep quality with long sleep latency as the component with the highest proportion (57,3%). Poor sleep qualities are more frequent in patients within the age range of 18-39 years rather than older patients. This study also finds that higher hypertension grade appears more often as the sleep quality gets worse. With this study, hopefully Puskesmas II Denpasar Barat could emphasize the importance of sleep quality as a preventive act towards fighting hypertension. Keywords: Hypertension, Quality of Sleep
Hubungan antara Kadar Asam Urat dengan Profil Lipid pada Pasien Sindrom Koroner Akut di RSUD Sanjiwani Gianyar I Gusti Ngurah Bayu Paramartha; I Gede Bagus Gita Pranata Putra; Sri Ratna Dewi
AMJ (Aesculapius Medical Journal) Vol. 3 No. 3 (2023): October
Publisher : Fakultas Ilmu Kedokteran dan Ilmu Kesehatan, Universitas Warmadewa

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Abstract

AbstractThe Correlation Between Uric Acid and Lipid Profile in Acute Coronary Syndrome Patient of Sanjiwani Hospital GianyarSeveral studies show that high uric acid levels is linking to the incidence of acute coronary syndromes and dyslipidemia that leads to heart disease. The aim of this study is to determine the association between uric acid and lipid profile in acute coronary syndrome patients of Sanjiwani Hospital Gianyar. Cross-sectional analysis is the type of data analysis that is being used in this study and was conducted at the Sanjiwani Hospital, Gianyar, with a total of 45 subjects involved. Spearman correlation test showed that there was a significant positive correlation between uric acid levels and Total Cholesterol (TC) (r = 0.467 and p = 0.001). There was a significant positive correlation between uric acid levels and Low Density Lipoprotein (LDL) (r= 0.348 and p value = 0.019). There was a significant negative correlation between uric acid levels and High Density Lipoprotein (HDL) (r= -0.445 and p = 0.002). There was no significant correlation between uric acid levels and Triglycerides (TG) (r = 0.232 and p = 0.124). It was also found that more than 50% of subjects had uric acid levels in the high category (53.3%), optimal Total Cholesterol (TC) levels (80%), normal High Density Lipoprotein (HDL) levels (57.8%), and optimal Triglycerides (TG) levels (71.1%). Meanwhile, 46.7% of subjects had optimal Low Density Lipoprotein (LDL) levels.