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All Journal Indonesian Journal of Medicine Jurnal Bidan Pintar (JuBiTar) Strada Jurnal Ilmiah Kesehatan (SJIK)
Ambar Dwi Retnoningrum
STIKes Satria Bhakti Nganjuk
Dentistry Education Health Professions Medicine & Pharmacology Nursing Public Health Social Sciences

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The Effects of Glucomannan Hydrolysates and BV Gel on Nugent Score, Treg Cell Percentage, and TGF-? level in Bacterial Vaginosis Retnoningrum, Ambar Dwi; Nurseta, Tatit; Prawiro, Sumarno Reto; Endharti, Agustina Tri; Wahyuni, Endang Sri
Indonesian Journal of Medicine Vol 3, No 1 (2018)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (690.183 KB)

Abstract

Background: Bacterial vaginosis is commonly experienced by women of reproductive age. The Nugent score is the gold standard for diagnosing bacterial vaginosis. Prebiotic Glucomannan hydrolysates (GMH) as a therapy in the treatment of bacterial vaginosis and has an immunomodulatory effect on the immune system and provides cellular immunity. The purpose of this study was to examine the effects of GMH and BV Gel on Nugent scores, Treg cell presentation, and TGF ? levels in bacterial vaginosis of women of childbearing age.Subjects and Method: This was an experimental study. A sample of 24 women aged 20 to 45 years old with bacterial vaginosis (Nugent score ?7) was divided into 4 groups: oral antibiotic group metronidazole (500mg), combination of GMH (300mg) and metronidazole, 5 ml BV Gel tube, and combination of GMH and BV Gel scores. The dependent variables were GMH and BV Gel administrations. The independent variables Nugent score, Treg presentation, and TGF-? level. Nugent score, Treg cell presentation, and TGF ? level were measured on day-0, day-11, and day-22. The data were analyzed by one way Anova.Results: The results of the analysis after treatment on day 22 showed that the GMH and BV gel were able to reduce Nugent scores, increase Treg cell presentation and TGF ? levels in bacterial vaginosis of women of childbearing age.Conclusion: GMH as an alternative therapy for bacterial vaginosis compared with antibiotic treatment can improve normal vaginal flora and stimulate the immune system in vitro and in vivo significantly.Keywords: Glucomannan Hydrolysates, BV Gel, Nugent sel Treg score, TGF ?Correspondence:Ambar Dwi Retnoningrum. Masters Program of Midwifery, Universitas Brawijaya, Malang, East Java. Email: adreambar@gmail.com. Mobile: +6281335743696.Indonesian Journal of Medicine (2018), 3(1): 33-43https://doi.org/10.26911/theijmed.2018.03.01.05
APAKAH FAKTOR BIOLOGI, SOSIAL, EKONOMI BERHUBUNGAN DENGAN RESIKO KEJADIAN STUNTING PADA BALITA? Retnoningrum, Ambar Dwi
Jurnal Bidan Pintar Vol 2, No 1 (2021): April 2021
Publisher : Universitas Kadiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30737/jubitar.v2i1.1651

Abstract

Stunting merupakan salah satu bentuk malnutrisi yang sering dihadapi oleh negara berkembang. Faktor internal keluarga dapat memberikan dampak pada balita stunting Tujuan penelitian ini untuk mengetahui pengaruh faktor biologi, sosial, ekonomi terhadap kejadian stunting di Kabupaten Nganjuk. Desain penelitian ini menggunakan penelitian analitik observasional dengan rancangan case control. Lokasi penelitian di Kabupaten Nganjuk pada bulan Mei sampai  Juni 2020. Jumlah sampel 150 balita dipilih dengan menggunakan fixed disease sampling yang meliputi kelompok kasus  50 balita dengan stunting dan kelompok kontrol sebanyak 100 balita normal yang tidak dalam kondisi stunting, wasting dan overweight. Variabel independen penelitian ini panjang badan lahir, pemberian ASI eksklusif, jumlah keluarga dan pendapatan keluarga, sedangkan variabel dependen penelitian kasus stunting. Alat pengumpulan data menggunakan kuesioner dan pengolahan data menggunakan analisis regresi logistik ganda. Stunting dipengaruhi oleh panjang badan lahir (OR=2.47; CI 95%=1.21 hingga 3.72; p=<0.000), pemberian ASI (OR=1.78; CI 95%=0.52 hingga 3.04; p=0.006), jumlah keluarga (OR=2.31; CI 95%=1.69 hingga 2.93; p=<0.000), dan pendapatan keluarga (OR=2.16; CI 95%=0.95 hingga 3.37; p=0.011). Kejadian stunting meningkat  dengan panjang badan lahir kurang, menyusui tidak eksklusif, jumlah keluarga yang banyak dan rendahnya pendapatan keluarga. Kata kunci : Stunting, balita, biologi, sosial, ekonomi         
Method (Stimulation Endorphin, Oxytosin and Sugestive) to Increase The Production of Breast Milk and Involution of Uters On Post Partum Sefrina Rukmawati; Puji Astutik; Ambar Dwi Retnoningrum
STRADA : Jurnal Ilmiah Kesehatan Vol. 9 No. 2 (2020): November
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjik.v9i2.310

Abstract

This research uses quasi experiment post test only design. The study used consecutive sampling. The independent variable Method (Stimulation Endorphin,Oxytosin and Sugestive), dependent variable Smoothness of breast milk and Uteric Involution. data collection using observation sheets. The study population and sample were 30 respondents with purposive sampling technique. The results of the study of 30 respondents, 15 respondents were not given speos method therapy almost all respondents, namely 13 respondents not producing smooth milk (86.6%) and 10 respondents were abnormal Uterus (66.67%), while 15 respondents were given Method (Stimulation endorphin, oxytocin and suggestive) almost All respondents, 14 respondents, were producing breast milk smoothly (93.3%). T-test results obtained pvalue = 0,000 ≤ α = (0.05), so that Ha is accepted. There is an influence of Method (Stimulation endorphin, oxytocin and suggestive) to increase milk production and involution of the uterus in post partum
Co-Authors Agustina Tri Endharti Dewi Indriani Muhammad Rivai Prawiro, Sumarno Reto Puji Astutik Sefrina Rukmawati Tatit Nurseta