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All Journal Indonesian Journal of Global Health research Jurnal Farmasi Jurnal Locus Penelitian dan Pengabdian Indonesian Journal on Medical Science (IJMS) Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat
Truly Dian Anggraini
Sekolah Tinggi Ilmu Kesehatan Nasional
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Tingkat Kepatuhan Penggunaan Obat Antidiabetik Pada Pasien Diabetes Melitus Tipe 2 Di Apotek Sehat Kabupaten Boyolali Truly Dian Anggraini; Novita Puspasari - Sekolah Tinggi Ilmu Kesehatan Nasional
Indonesian Journal on Medical Science Vol 6 No 2 (2019): IJMS 2019
Publisher : Unit Penelitian dan Pengabdian Masyarakat Politeknik Kesehatan Bhakti Mulial

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Abstract : Diabetes mellitus is a chronic disease that occurs when the body cannot produce enough insulin or cannot use insulin effectively. Based on data from IDF (2015), Indonesia ranks 7th with the highest diabetes mellitus in the world. In long-term diseases such as diabetes mellitus, adherence to drug use is one of the factors in the success of therapy. This study was conducted with the aim to describe the level of adherence to the use of antidiabetic drugs in patients with type 2 diabetes mellitus at the Healthy Pharmacy Banyudono Boyolali. This type of research is descriptive research conducted prospectively. Data retrieval uses the Morisky Medication Adherence Scale-8 (MMAS-8) questionnaire on 67 respondents. Data analysis was performed statistically and presented in the form of a percentage. The results obtained by the level of adherence to the use of antidiabetic drugs in patients with type 2 diabetes mellitus in the Healthy Pharmacy Banyudono Boyolali was in the category of low adherence level as many as 34 respondents (50.7%), moderate adherence level category as many as 21 respondents (31.3%), and the high adherence level category was 12 respondents (17.9%). Based on the results of the study, most patients with type 2 diabetes mellitus at the Sehat Pharmacy Banyudono Boyolali had a low level of adherence to the use of antidiabetic drugs, namely 34 respondents (50.7%).Key words : antidiabetic, diabetes mellitus, level of adherence Abstrak : Diabetes melitus adalah penyakit kronis yang terjadi ketika tubuh tidak dapat memproduksi insulinyang cukup atau tidak bisa menggunakan insulin dengan efektif. Berdasarkan data dari IDF (2015), Indonesia menempati peringkat ke 7 dengan penderita diabetes melitus tertinggi di dunia. Pada penyakit jangka panjang seperti diabetes melitus, kepatuhan penggunaan obat merupakan salah satu faktor keberhasilan terapi. Penelitian ini dilakukan dengan tujuan untuk mengetahui gambaran tingkat kepatuhan penggunaan obat antidiabetik pada pasien diabetes melitus tipe 2 di Apotek Sehat Banyudono Boyolali.Jenis penelitian ini adalah penelitian deskriptif yang dilakukan secara prospektif. Pengambilan data menggunakan kuesioner Morisky Medication Adherence Scale-8 (MMAS-8) terhadap 67 responden. Analisis data dilakukan secara statistik dean disajikan dalam bentuk presentase . Hasil penelitian diperoleh tingkat kepatuhan penggunaan obat antidiabetik pada pasien diabetes melitus tipe 2 di Apotek Sehat Banyudono Boyolali adalah pada kategori tingkat kepatuhan rendah sebanyak 34 responden (50,7%), kategori tingkat kepatuhan sedang sebanyak 21 responden (31,3%), dan kategori tingkat kepatuhan tinggi sebanyak 12 responden (17,9%). Berdasarkan hasil penelitian sebagian besarpasien diabetes melitus tipe 2 di Apotek Sehat Banyudono Boyolali mempunyai tingkat kepatuhan penggunaan obat antidiabetik kategori rendah yaitu sebanyak 34 responden (50,7%).Kata kunci : antidiabetik, diabetes melitus, tingkat kepatuhan
Analisis Faktor Yang Mempengaruhi Pengetahuan Tenaga Teknis Kefarmasian Tentang Hepatitis B Di Kabupaten Sragen Truly Dian Anggraini; Susilowati Susilowati; Risna Intan Melati-Sekolah Tinggi Ilmu Kesehatan Nasional
Indonesian Journal on Medical Science Vol 8 No 1 (2021): IJMS 2021
Publisher : Unit Penelitian dan Pengabdian Masyarakat Politeknik Kesehatan Bhakti Mulial

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Abstract: Hepatitis B was a disease caused by hepatitis B virus infection and caused liver inflammation, and it can also resulted in chronic hepatitis, cirrhosis, and hepatocellular carcinoma. The resulted of Riskesdas in 2013 showed that hepatitis prevalence in Indonesia in 2013 by 1,2% increased twice compared to Riskesdas in 2007, which amount to 0,6%. The most common type of hepatitis that infected the population of Indonesia is hepatitis B by 21,8%. According to research conducted by Ogundele et al. (2017), the precautioned of any disease was proportional to knowledge, behavior, and practiced, hence oversight that resulted in the transmission of disease can be reduced by having good knowledge. Pharmaceutical Technical Personnel was one part of the health labor that had a role in pharmaceutical services. The purpose of this study was to established the level of knowledge of Pharmaceutical Technical Personnel about hepatitis B in Sragen Regency. This researched was classified of non-experimental researched by divided questionnaires and then analyzed descriptively about each respondent's characteristics and analyzed for the predictor factors. A total of Pharmaceutical Technical Workers is 123, there are 103 people (83.74%) who had a good knowledge categorized, and as many as 20 people (16.26%) had a poor knowledge categorized about hepatitis B, and the respondent's labor was the most significant predictorns.Keywords : Knowledge, Hepatitis B, Pharmaceutical Technical Personnel, Predictor Factors  Abstrak: Hepatitis B adalah penyakit yang disebabkan karena infeksi virus hepatitis B dan menyebabkan inflamasi pada hati, dapat juga berakibat hepatitis kronis, sirosis, dan karsinoma hepatoselular. Hasil Riskesdas tahun 2013 menunjukkan bahwa prevalensi hepatitis di Indonesia tahun 2013 sebesar 1,2% meningkat dua kali dibandingkan Riskesdas tahun 2007 yang sebesar 0,6%. Jenis hepatitis yang banyak menginfeksi penduduk Indonesia adalah hepatitis B sebesar 21,8%. Menurut penelitian yang dilakukan oleh Ogundele, dkk (2017), pencegahan penyakit apapun adalah sebanding dengan pengetahuan, sikap, dan praktik dan karenanya kelalaian yang mengakibatkan tertularnya penyakit dapat berkurang dengan pengetahuan yang baik. Tenaga Teknis Kefarmasian merupakan salah satu bagian dari tenaga kesehatan yang mempunyai peran dalam pelayanan kefarmasian. Tujuan dari penelitian ini adalah untuk mengetahui faktor yang mempengaruhi tingkat pengetahuan Tenaga Teknis Kefarmasian tentang hepatitis B di kabupaten Sragen. Penelitian ini merupakan jenis penelitian analitik tipe cohort, dengan menyebar kuesioner kemudian dianalisis secara deskriptif mengenai masing-masing karakteristik responden dan di analisa untuk faktor prediktornya. Sejumlah 123 Tenaga Teknis Kefarmasian, terdapat 103 orang (83,74%) yang memiliki kategori pengetahuan baik dan sebanyak 20 orang (16,26%) memiliki kategori pengetahuan kurang baik tentang hepatitis B, dan tempat bekerja responden merupakan faktor prediktor yang paling signifikan.Kata kunci : Pengetahuan, Hepatitis B, Tenaga Teknis Kefarmasian, Faktor Prediktor
Kajian Etnofarmasi Penggunaan Tumbuhan Obat Sebagai Alternatif Pengobatan Diare Oleh Masyarakat Suku Osing Dusun Krajan Amira Septa Sanjaya; Hartono Hartono; Truly Dian Anggraini
Jurnal Farmasi (Journal of Pharmacy) Vol 12, No 1 (2023)
Publisher : SEKOLAH TINGGI ILMU KESEHATAN NASIONAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37013/jf.v12i1.203

Abstract

Diarrhea is a disease whose existence is still a global health problem, including Indonesia. Diarrhea is in the top 10 diseases that still occur frequently and is ranked 5th in the Osing Tribe. For the treatment of diarrhea, the Osing tribe still uses plants as medicinal plants that are used for generations. This study was conducted to examine how ethnopharmacy in the Osing tribe is intended as a preliminary study for the development of traditional medicine carried out by the Osing tribe as traditional medicine/phytopharmaca. This research is a descriptive study using qualitative methods with sampling techniques using snowball sampling through open-ended interviews by filling out informant information sheets and involving 22 informants from the Osing Tribe, Krajan hamlet, Kemiren, Glagah, Banyuwangi, East Java. The results of the ethnopharmaceutical research in the Osing Tribe showed that there were 8 types of plants and an analysis was carried out using ICF (Informant Consensus Factor) with the results of 0.6 being interpreted as being trusted and used as a hereditary treatment, PPV (Plant Part Value) to calculate the plant part used. with a yield of 50% leaves, 23% fruit, 27% rhizome and FL (Fidelity Level) to determine the types of plants most often used in treating diarrhea with the highest yield of 100%, including Psidium guajava L and Manihot esculenta.
KESESUAIAN PROSES REKONSTITUSI ANTIBIOTIK INJEKSI DI BANGSAL ANAK RUMAH SAKIT UMUM (RSU) ASSALAM GEMOLONG SRAGEN Mustika Anggrahini; Truly Dian Anggraini
Jurnal Farmasindo Vol 6 No 1 (2022): Juni
Publisher : Program Studi D3 Farmasi Politeknik Indonusa Surakarta

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Abstract

Proses rekonstitusi adalah proses pencampuran medium pelarut kedalam masa serbuk kering hingga menghasilkan zat tersuspensi yang dilakukan secara aseptik. Penelitian ini bertujuan untuk mengetahui kesesuaian proses rekonstitusi antibiotik injeksi serbuk kering di bangsal anak RSU Assalam Gemolong. Penelitian ini merupakan penelitian deskriptif menggunakan teknik sampling jenuh dengan pengumpulan data pengamatan secara langsung menggunakan checklist selama satu bulan. Hasil penelitian menunjukkan persentase kesesuaian proses rekonstitusi antibiotik injeksi berdasarkan SPO & Panduan Pencampuran Obat RSU Assalam Gemolong yaitu pada kesesuaian perhitungan dosis, pemilihan jenis pelarut dan penyimpanan setelah di rekonstitusi (100%), kesesuaian pada perhitungan volume pelarut (62,63%), kesesuaian pada pembuatan label obat (76,77%), kesesuaian pada pencampuran obat secara aseptis (58,58%), serta kesesuaian pada pembuangan semua bekas pencampuran obat (88,89%). Sedangkan berdasarkan Pediatric Injectable Drug 10th edition & Handbook on Injectable Drugs 17th edition diperoleh hasil penelitian yaitu kesesuaian pada perhitungan dosis (90,91%), kesesuaian pada pemilihan jenis pelarut dan pada penyimpanan setelah direkonstitusi (100%), serta kesesuaian pada perhitungan volume pelarut (58,59%). Maka persentase kesesuaian proses rekonstitusi antibiotik injeksi berdasarkan SPO & Panduan Pencampuran Obat RSU AssalamGemolong yaitu 83,84% dari 7 aspek pengamatan, Sedangkan berdasarkan Pediatric Injectable Drug 10th edition & Handbook on Injectable Drugs 17th edition yaitu 87,37% dari 4 aspek pengamatan.
Rationality of Antibiotic use in Patients with Urinary Tract Infections at the Dr Oen Kandang Sapi Hospital Inpatient Truly Dian Anggraini; Rista Ariyani
Indonesian Journal of Global Health Research Vol 5 No 4 (2023): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v5i4.2526

Abstract

Urinary tract infection is an infectious disease that requires antibiotics in its treatment. In Indonesia, UTI cases reach 180,000 cases per year. The aim of the research is to determine the pattern of antibiotic use and the appropriateness of antibiotic use in UTI patients at Dr Oen Kandang Sapi Hospital in 2021. The method used is non-experimental by collecting data retrospectively from medical records of patients diagnosed with UTI in 2021, then the data is analyzed using the method Gyssens. and analyzed quantitatively descriptively. The results of this study were an analysis of the accuracy of antibiotics using the Gyssens method in UTI patients at DR Oen Kandang Sapi Hospital, with 45 rational prescriptions (54.88%) and 37 irrational prescriptions (45.12%). Inaccuracy in the IVA category was 2 prescriptions, IVC was 8 prescriptions, in category IIIA was 1 prescription, in category IIIB was 3 prescriptions, category IVA, IVC was 8 prescriptions, category IVC, IIIB was 5 prescriptions, category IVA, IVC, IIIB was 9 recipes, category IIA, IIB 1 recipe, category IVA, IVC, IIB 1 recipe. The conclusion of this study is that the most widely used UTI antibiotic is a single type of antibiotic with 67 prescriptions (81.71%), the most widely used class of antibiotic is the cephalosporin class of antibiotics with 60 prescriptions (61.22%), the most common type of antibiotic. The antibiotic ceftriaxone used was 42 prescriptions (42.42%).
PENETAPAN KADAR FLAVONOID TOTAL INFUSA RAMBUT JAGUNG MANIS (Zea mays Saccharata Sturt) MENGGUNAKAN SPEKTROFOTOMETRI UV-VIS SECARA KOLORIMETRI Anita Mursiany; Recta Olivia Umboro; Truly Dian Anggraini
Jurnal Locus Penelitian dan Pengabdian Vol. 2 No. 12 (2023): jurnal locus penelitian dan pengabdian
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/locus.v2i12.2354

Abstract

Rambut jagung manis selama ini dianggap sebagai limbah dan belum dimanfaatkan secara optimal. Hasil penelitian menunjukkan bahwa ekstrak air rambut jagung muda umur 40 hari dan rambut jagung umur 60 hari mengandung senyawa flavonoid, alkaloid, saponin, tanin, dan fenol. Penelitian ini bertujuan untuk mengetahui kandungan total flavonoid pada infusa rambut jagung manis (Zea mays Saccharata Sturt). Metode penelitian yang digunakan adalah penentuan kadar flavonoid total yang dilakukan secara Spektrofotometri UV-Vis secara kolorimetri. Kandungan total flavonoid dalam (mgQE/g ekstrak) berturut-turut adalah 0,0061, 0,0047, 0,0085, dan dalam persen (%) 0,61, 0,47, 0,85. Sehingga dapat disimpulkan bahwa infusa rambut jagung manis (Zea mays Saccharata Sturt) mengandung senyawa flavonoid dan rata-rata kadar flavonoid total sebesar 0,0064 ± 0,0019 mgQE/g ekstrak dengan persentase sebesar 0,6433 ± 0,1921%.
Analysis of the Relationship of Drug Related Problems (DRPS) of Amlodipin Medicine Dosage Category on Geriatries' Blood Pressure Accomplishments Retnowati Adiningsih; Truly Dian Anggraini; Elisabeth Septia Andini; Eliza Dian Hapsari
Indonesian Journal of Global Health Research Vol 7 No 1 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i1.4858

Abstract

The increase in the number of geriatrics leads to an increase in health problems, one of which is related to hypertension. Hypertension is an important risk factor for cardiovascular disease morbidity and mortality that is often found in geriatrics. The class of drugs that are widely used to reduce blood pressure and have the potential to cause DRPs is the Calcium channel blocker (CCB) class of drugs, namely amlodipine. Objective: The purpose of this study was to analyze the relationship of Drug related problems (DRPs) in the single dose category in the use of amlodipine drugs to the achievement of geriatric blood pressure targets. Method: This study is a descriptive study using a cross-sectional observational design that is analytic in nature. Sampling using purposive sampling technique. The data analysis used was univariate and bivariate analysis. Result: The results showed that 70% of patients were female, 40% were over 70 years old and 70% of patients had stage 2 hypertension. There was 1 patient who experienced drug related problems (DRPs) in the drug dosage category with the result that the blood pressure target was not achieved and 1 patient who received the right dose of amlodipine with the result that the blood pressure target was not achieved. Conclusion: From the results of the study it can be concluded that there is no significant relationship between Drug Related Problems (DRPs) in the category of amlodipine drug dosage with the achievement of geriatric blood pressure targets (p = 0.35).
Co-Authors Amira Septa Sanjaya Anita Mursiany Elisabeth Septia Andini Eliza Dian Hapsari Hartono Hartono Mustika Anggrahini Novita Puspasari - Sekolah Tinggi Ilmu Kesehatan Nasional Recta Olivia Umboro Retnowati Adiningsih Risna Intan Melati-Sekolah Tinggi Ilmu Kesehatan Nasional Rista Ariyani Susilowati Susilowati