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All Journal Farmasains : Jurnal Ilmiah Ilmu Kefarmasian PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Indonesian Journal of Global Health research Lumbung Farmasi : Jurnal Ilmu Kefarmasian Jurnal Farmasi Indonesian Journal on Medical Science (IJMS)
Truly Dian Anggraini
Sekolah Tinggi Ilmu Kesehatan Nasional
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Tingkat Kepatuhan Penggunaan Obat Antidiabetik Pada Pasien Diabetes Melitus Tipe 2 Di Apotek Sehat Kabupaten Boyolali Truly Dian Anggraini; Novita Puspasari - Sekolah Tinggi Ilmu Kesehatan Nasional
Indonesian Journal on Medical Science Vol 6 No 2 (2019): IJMS 2019
Publisher : Unit Penelitian dan Pengabdian Masyarakat Politeknik Kesehatan Bhakti Mulial

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Abstract : Diabetes mellitus is a chronic disease that occurs when the body cannot produce enough insulin or cannot use insulin effectively. Based on data from IDF (2015), Indonesia ranks 7th with the highest diabetes mellitus in the world. In long-term diseases such as diabetes mellitus, adherence to drug use is one of the factors in the success of therapy. This study was conducted with the aim to describe the level of adherence to the use of antidiabetic drugs in patients with type 2 diabetes mellitus at the Healthy Pharmacy Banyudono Boyolali. This type of research is descriptive research conducted prospectively. Data retrieval uses the Morisky Medication Adherence Scale-8 (MMAS-8) questionnaire on 67 respondents. Data analysis was performed statistically and presented in the form of a percentage. The results obtained by the level of adherence to the use of antidiabetic drugs in patients with type 2 diabetes mellitus in the Healthy Pharmacy Banyudono Boyolali was in the category of low adherence level as many as 34 respondents (50.7%), moderate adherence level category as many as 21 respondents (31.3%), and the high adherence level category was 12 respondents (17.9%). Based on the results of the study, most patients with type 2 diabetes mellitus at the Sehat Pharmacy Banyudono Boyolali had a low level of adherence to the use of antidiabetic drugs, namely 34 respondents (50.7%).Key words : antidiabetic, diabetes mellitus, level of adherence Abstrak : Diabetes melitus adalah penyakit kronis yang terjadi ketika tubuh tidak dapat memproduksi insulinyang cukup atau tidak bisa menggunakan insulin dengan efektif. Berdasarkan data dari IDF (2015), Indonesia menempati peringkat ke 7 dengan penderita diabetes melitus tertinggi di dunia. Pada penyakit jangka panjang seperti diabetes melitus, kepatuhan penggunaan obat merupakan salah satu faktor keberhasilan terapi. Penelitian ini dilakukan dengan tujuan untuk mengetahui gambaran tingkat kepatuhan penggunaan obat antidiabetik pada pasien diabetes melitus tipe 2 di Apotek Sehat Banyudono Boyolali.Jenis penelitian ini adalah penelitian deskriptif yang dilakukan secara prospektif. Pengambilan data menggunakan kuesioner Morisky Medication Adherence Scale-8 (MMAS-8) terhadap 67 responden. Analisis data dilakukan secara statistik dean disajikan dalam bentuk presentase . Hasil penelitian diperoleh tingkat kepatuhan penggunaan obat antidiabetik pada pasien diabetes melitus tipe 2 di Apotek Sehat Banyudono Boyolali adalah pada kategori tingkat kepatuhan rendah sebanyak 34 responden (50,7%), kategori tingkat kepatuhan sedang sebanyak 21 responden (31,3%), dan kategori tingkat kepatuhan tinggi sebanyak 12 responden (17,9%). Berdasarkan hasil penelitian sebagian besarpasien diabetes melitus tipe 2 di Apotek Sehat Banyudono Boyolali mempunyai tingkat kepatuhan penggunaan obat antidiabetik kategori rendah yaitu sebanyak 34 responden (50,7%).Kata kunci : antidiabetik, diabetes melitus, tingkat kepatuhan
Analisis Faktor Yang Mempengaruhi Pengetahuan Tenaga Teknis Kefarmasian Tentang Hepatitis B Di Kabupaten Sragen Truly Dian Anggraini; Susilowati Susilowati; Risna Intan Melati-Sekolah Tinggi Ilmu Kesehatan Nasional
Indonesian Journal on Medical Science Vol 8 No 1 (2021): IJMS 2021
Publisher : Unit Penelitian dan Pengabdian Masyarakat Politeknik Kesehatan Bhakti Mulial

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Abstract

Abstract: Hepatitis B was a disease caused by hepatitis B virus infection and caused liver inflammation, and it can also resulted in chronic hepatitis, cirrhosis, and hepatocellular carcinoma. The resulted of Riskesdas in 2013 showed that hepatitis prevalence in Indonesia in 2013 by 1,2% increased twice compared to Riskesdas in 2007, which amount to 0,6%. The most common type of hepatitis that infected the population of Indonesia is hepatitis B by 21,8%. According to research conducted by Ogundele et al. (2017), the precautioned of any disease was proportional to knowledge, behavior, and practiced, hence oversight that resulted in the transmission of disease can be reduced by having good knowledge. Pharmaceutical Technical Personnel was one part of the health labor that had a role in pharmaceutical services. The purpose of this study was to established the level of knowledge of Pharmaceutical Technical Personnel about hepatitis B in Sragen Regency. This researched was classified of non-experimental researched by divided questionnaires and then analyzed descriptively about each respondent's characteristics and analyzed for the predictor factors. A total of Pharmaceutical Technical Workers is 123, there are 103 people (83.74%) who had a good knowledge categorized, and as many as 20 people (16.26%) had a poor knowledge categorized about hepatitis B, and the respondent's labor was the most significant predictorns.Keywords : Knowledge, Hepatitis B, Pharmaceutical Technical Personnel, Predictor Factors  Abstrak: Hepatitis B adalah penyakit yang disebabkan karena infeksi virus hepatitis B dan menyebabkan inflamasi pada hati, dapat juga berakibat hepatitis kronis, sirosis, dan karsinoma hepatoselular. Hasil Riskesdas tahun 2013 menunjukkan bahwa prevalensi hepatitis di Indonesia tahun 2013 sebesar 1,2% meningkat dua kali dibandingkan Riskesdas tahun 2007 yang sebesar 0,6%. Jenis hepatitis yang banyak menginfeksi penduduk Indonesia adalah hepatitis B sebesar 21,8%. Menurut penelitian yang dilakukan oleh Ogundele, dkk (2017), pencegahan penyakit apapun adalah sebanding dengan pengetahuan, sikap, dan praktik dan karenanya kelalaian yang mengakibatkan tertularnya penyakit dapat berkurang dengan pengetahuan yang baik. Tenaga Teknis Kefarmasian merupakan salah satu bagian dari tenaga kesehatan yang mempunyai peran dalam pelayanan kefarmasian. Tujuan dari penelitian ini adalah untuk mengetahui faktor yang mempengaruhi tingkat pengetahuan Tenaga Teknis Kefarmasian tentang hepatitis B di kabupaten Sragen. Penelitian ini merupakan jenis penelitian analitik tipe cohort, dengan menyebar kuesioner kemudian dianalisis secara deskriptif mengenai masing-masing karakteristik responden dan di analisa untuk faktor prediktornya. Sejumlah 123 Tenaga Teknis Kefarmasian, terdapat 103 orang (83,74%) yang memiliki kategori pengetahuan baik dan sebanyak 20 orang (16,26%) memiliki kategori pengetahuan kurang baik tentang hepatitis B, dan tempat bekerja responden merupakan faktor prediktor yang paling signifikan.Kata kunci : Pengetahuan, Hepatitis B, Tenaga Teknis Kefarmasian, Faktor Prediktor
Kajian Etnofarmasi Penggunaan Tumbuhan Obat Sebagai Alternatif Pengobatan Diare Oleh Masyarakat Suku Osing Dusun Krajan Amira Septa Sanjaya; Hartono Hartono; Truly Dian Anggraini
Jurnal Farmasi (Journal of Pharmacy) Vol 12, No 1 (2023)
Publisher : SEKOLAH TINGGI ILMU KESEHATAN NASIONAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37013/jf.v12i1.203

Abstract

Diarrhea is a disease whose existence is still a global health problem, including Indonesia. Diarrhea is in the top 10 diseases that still occur frequently and is ranked 5th in the Osing Tribe. For the treatment of diarrhea, the Osing tribe still uses plants as medicinal plants that are used for generations. This study was conducted to examine how ethnopharmacy in the Osing tribe is intended as a preliminary study for the development of traditional medicine carried out by the Osing tribe as traditional medicine/phytopharmaca. This research is a descriptive study using qualitative methods with sampling techniques using snowball sampling through open-ended interviews by filling out informant information sheets and involving 22 informants from the Osing Tribe, Krajan hamlet, Kemiren, Glagah, Banyuwangi, East Java. The results of the ethnopharmaceutical research in the Osing Tribe showed that there were 8 types of plants and an analysis was carried out using ICF (Informant Consensus Factor) with the results of 0.6 being interpreted as being trusted and used as a hereditary treatment, PPV (Plant Part Value) to calculate the plant part used. with a yield of 50% leaves, 23% fruit, 27% rhizome and FL (Fidelity Level) to determine the types of plants most often used in treating diarrhea with the highest yield of 100%, including Psidium guajava L and Manihot esculenta.
Analysis of the Relationship of Drug Related Problems (DRPS) of Amlodipin Medicine Dosage Category on Geriatries' Blood Pressure Accomplishments Retnowati Adiningsih; Truly Dian Anggraini; Elisabeth Septia Andini; Eliza Dian Hapsari
Indonesian Journal of Global Health Research Vol 7 No 1 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i1.4858

Abstract

The increase in the number of geriatrics leads to an increase in health problems, one of which is related to hypertension. Hypertension is an important risk factor for cardiovascular disease morbidity and mortality that is often found in geriatrics. The class of drugs that are widely used to reduce blood pressure and have the potential to cause DRPs is the Calcium channel blocker (CCB) class of drugs, namely amlodipine. Objective: The purpose of this study was to analyze the relationship of Drug related problems (DRPs) in the single dose category in the use of amlodipine drugs to the achievement of geriatric blood pressure targets. Method: This study is a descriptive study using a cross-sectional observational design that is analytic in nature. Sampling using purposive sampling technique. The data analysis used was univariate and bivariate analysis. Result: The results showed that 70% of patients were female, 40% were over 70 years old and 70% of patients had stage 2 hypertension. There was 1 patient who experienced drug related problems (DRPs) in the drug dosage category with the result that the blood pressure target was not achieved and 1 patient who received the right dose of amlodipine with the result that the blood pressure target was not achieved. Conclusion: From the results of the study it can be concluded that there is no significant relationship between Drug Related Problems (DRPs) in the category of amlodipine drug dosage with the achievement of geriatric blood pressure targets (p = 0.35).
EFEK SITOTOKSISITAS DAN SELEKTIVITAS FRAKSI AKTIF EKSTRAK DAUN KELOR (Moringa oleifera Lamk.) TERHADAP SEL KANKER PAYUDARA T47D Susilowati Susilowati; Truly Dian Anggraini
Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Vol. 5 No. 2 (2018)
Publisher : Universitas Muhammadiyah Prof. DR. HAMKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/farmasains.v5i2.2149

Abstract

Penelitian sebelumnya menunjukkan ekstrak daun kelor dan fraksinya memiliki kandungan flavonoid dan fenolik yang memiliki potensi sebagai antioksidan. Antioksidan diketahui memiliki kemampuan untuk mereduksi radikal bebas yang merupakan salah satu penyebab kerusakan protein dan DNA sehingga mengakibatkan timbulnya kanker. Pada penelitian ini potensi antikanker payudara daun kelor dilakukan melalui uji sitotoksik terhadap sel kanker payudara T47D dan potensi keamanan melalui selektivitasnya terhadap sel normal secara in vitro. Tahap pertama penelitian ini meliputi pembuatan ekstrak kental daun kelor dengan metode maserasi menggunakan pelarut metanol dan dilanjutkan dengan fraksinasi hingga diperoleh fraksi air dan fraksi etil asetat. Tahap kedua dilakukan uji Sitotoksik ekstrak dan fraksi daun kelor terhadap Sel T47D dan Sel Vero. Analisis data yang dilakukan meliputi analisis potensi antikanker payudara melalui nilai IC50 dari uji sitotoksik dan analisis keamananya melalui Selectivity Index (SI). Hasil penelitian menunjukkan bahwa aktivitas sitotoksik fraksi etil asetat daun kelor dapat menghambat pertumbuhan sel T47D lebih baik dibandingkan dengan fraksi airnya. Kedua fraksi daun kelor memiliki efek sitotoksik dan selektivitas yang rendah terhadap sel T47D dengan nilai IC50 fraksi air 499,42μg/mL dan fraksi etil asetat 289,47μg/mL serta nilai Selecticity Index secara berurutan 0,77 dan 1,01.
Gambaran Terapi Obat Pada Pasien Positif Covid-19 di RSUD Dr. Moewardi Surakarta Truly Dian Anggraini; Anita Mursiany; Jont Faisyal; Rani Millenia
Lumbung Farmasi: Jurnal Ilmu Kefarmasian Vol 6, No 1 (2025): Januari
Publisher : UNIVERSITAS MUHAMMADIYAH MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/lf.v6i1.23243

Abstract

Angka kejadian pasien terkonfirmasi positif COVID-19 mengalami peningkatan. BPOM telah menerbitkan panduan penatalaksanaan berupa informatorium Obat COVID-19 di Indonesia. Tujuan dari penelitian untuk mengetahui terapi obat yang digunakan pada pasien terkonfirmasi positif COVID-19 sedang di rawat inap di RSUD Dr. Moewardi pada tahun 2022. Merupakan penelitian deskriptif non eksperimental dengan pengambilan data secara retrospektif dari rekam medis pasien. Sampel pada penelitian ini sebanyak 82 pasien adalah semua pasien COVID-19 derajat keparahan sedang hingga derajat keparahan berat yang menjalani perawatan rawat inap di  RSUD Dr. Moewardi pada periode Februari – Juli 2022. Analisis data dengan rancangan deskriptif non-analitik, kemudian disajikan dalam bentuk prosentase. Hasil penelitian golongan obat yang digunakan yaitu antivirus sebanyak 100% dan antibiotik sebanyak 58,54%. Semua pasien mendapatkan vitamin dan mineral (vit C, vit d, dan Zink) sebanyak 100%. Obat tambahan yang diberikan sesuai dengan gejala penyakit adalah acetil sistein (98,78%), Enoxaparine (63,41%), Paracetamol (24,39%), omeprazole (17,07%), ranitidine (14,63%), VIP albumin (8,54%), sucralfate (7,32%), curcuma (7,72%), ondansetron (3,66%), metamizole (3,66%), dexametason (3,66%), metoclopropamide (2,44%), attapulgite (2,44%), ketorolac (2,44%), antasida (1,22%), lansoprazole (1,22%), lactulose (1,22%), codein (1,22), heparin (1,22%), asam tranexamat (1,22%), colchicine (1,22%), CaCO3 (1,22%) dan dimenhydrinate (1,22%).
Edukasi Penanggulangan Hipertensi dan Pemanfaatan Bahan Alam Berbasis Kearifan Lokal pada Petani Jambu Biji Merah di Jatirejo, Ngargoyoso: Education on Hypertension Management and the Utilization of Local Wisdom-Based Natural Resources for Red Guava Farmers in Jatirejo, Ngargoyoso Aulia Nur Rahmawati; Alip Desi Suyono Saputri; Truly Dian Anggraini; Bayu Kurniaaji; Pranichayudha Rohsulina
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 11 No. 6 (2026): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v11i6.12187

Abstract

Farmers in Jatirejo Village, Ngargoyoso, under the P4S Putra Jambu association, play a dual role as guava cultivators and agritourism educators. High physical demands and unhealthy lifestyles, such as smoking and high sugar/salt intake, increase the risk of hypertension and occupational stress, potentially hindering their productivity. This community service aims to enhance farmers' knowledge and awareness of hypertension prevention through health education and the utilization of local natural resources. Methods: The program was conducted in October 2025 and involved 27 farmers. Methods included education using the "Menjadi Petani Sehat" pocketbook, interactive Q&A sessions, and medical check-ups (blood pressure, blood glucose, and uric acid). Evaluation was measured via pre-test, post-test, and satisfaction questionnaires. The activity resulted in a 46.2% increase in farmers' knowledge. Medical screenings revealed that 81.8% of farmers were at risk of hypertension (BP ≥ 130/80 mmHg), and 52.4% had elevated blood sugar and uric acid levels. Participants responded very positively, with an 83.21% satisfaction rate. Education and health screenings are effective in improving farmers' understanding of healthy living, which is crucial for supporting sustainable agriculture and agritourism in Jatirejo Village.
Co-Authors Alip Desi Suyono Saputri Amira Septa Sanjaya Anita Mursiany Aulia Nur Rahmawati Elisabeth Septia Andini Eliza Dian Hapsari Hartono Hartono Jont Faisyal Kurniaaji, Bayu Mustika Anggrahini Novita Puspasari - Sekolah Tinggi Ilmu Kesehatan Nasional Pranichayudha Rohsulina Rani Millenia Retnowati Adiningsih Risna Intan Melati-Sekolah Tinggi Ilmu Kesehatan Nasional Susilowati Susilowati Susilowati Susilowati