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All Journal Jurnal Ilmu Dasar JFIOnline Indonesian Journal of Halal Research
Almawati Situmorang, Almawati
Fakultas Farmasi dan Sains Universitas Muhammadiyah Prof. Dr. HAMKA, Jakarta, Islamic Center, Jl. Delima II/IV, Klender Jakarta Timur 13460
Religion Biochemistry, Genetics & Molecular Biology Control & Systems Engineering Environmental Science Health Professions Mathematics Medicine & Pharmacology Other

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UJI DIFUSI MIKROEMULSI NITROGLISERIN MENGGUNAKAN TWEEN 80 SEBAGAI SURFAKTAN Yati, Kori; Situmorang, Almawati; Umoro, Ani
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 9, No 1 (2017): Punica Granatum
Publisher : Indonesian Research Gateway

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Abstract

ABSTRACT: Nitroglycerine is a drug of choice in the treatment of angina pectoris. Nitroglycerine has low dose, short time of plasma half life and liver metabolizing. This study used the formulation of microemulsion. The advantages of microemulsion transparent form, stable and has better skin penetration due to the smaller size of its droplet. This study aims at determining concentration of Tween 80 as surfactant as penetration in the nitroglycerine microemulsion. Tween 80 concentrations used were 40% (F1), 42,5% (F2) and 45% (F3). Penetration ability was tested by invitro using Franz diffusion cells. The results showed that 42,5% of the concentration of Tween 80 produces good penetration. F2 shows the measurement result of droplet size is 69,0 nm and diffusion test on the minutes of 180 for 86,00% ± 3,65. It can be concluded that the concentration of Tween 80 as surfactant of 42,5% gives microemulsion nitroglycerine with good penetration.
UJI DIFUSI MIKROEMULSI NITROGLISERIN MENGGUNAKAN TWEEN 80 SEBAGAI SURFAKTAN Yati, Kori; Situmorang, Almawati; Umoro, Ani
Jurnal Farmasi Indonesia Vol 9, No 1 (2017)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (9030.693 KB) | DOI: 10.35617/jfi.v9i1.557

Abstract

ABSTRACT: Nitroglycerine is a drug of choice in the treatment of angina pectoris. Nitroglycerine has low dose, short time of plasma half life and liver metabolizing. This study used the formulation of microemulsion. The advantages of microemulsion transparent form, stable and has better skin penetration due to the smaller size of its droplet. This study aims at determining concentration of Tween 80 as surfactant as penetration in the nitroglycerine microemulsion. Tween 80 concentrations used were 40% (F1), 42,5% (F2) and 45% (F3). Penetration ability was tested by invitro using Franz diffusion cells. The results showed that 42,5% of the concentration of Tween 80 produces good penetration. F2 shows the measurement result of droplet size is 69,0 nm and diffusion test on the minutes of 180 for 86,00% ± 3,65. It can be concluded that the concentration of Tween 80 as surfactant of 42,5% gives microemulsion nitroglycerine with good penetration.
Halal Identification for Meatballs in Pasar Tambun, Bekasi, West Java By Acrylamide Gels Hidayati, Wahyu; Apriaji, Meta; Situmorang, Almawati; Agustian, Ifany; Janah, Miftahul
Jurnal ILMU DASAR Vol 20 No 2 (2019)
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (180.445 KB) | DOI: 10.19184/jid.v20i2.9062

Abstract

Halal foods are important for Moslems and there is a Moslem’s duty to eat only Halal foods which is stated in Holly Qur’an. Moreover, government already made some regulations related to Halal certification which should be obeyed by food industries, including home industries. This research aimed to detect a porcine component in meatballs sold in Pasar Tradisional Tambun, Bekasi, West Java by using SDS-PAGE Here, we combined mechanical and chemistry methods to extract the proteins and compared the protein profiles on an acrylamide gel. We got specific bands of bovine and porcine proteins according to proteins bands that showed on the gel and after comparing with the samples we found that one sample had combining profiles in the extract. We concluded that three samples used in this research were halal, meanwhile, another sample containing porcine substances. Keywords: Halal, Proteins, Bovine, Porcine, Meatballs, SDS-PAGE.
The Effectiveness of Technical Guidance for Entrepreneurs in Small and Medium Enterprises in Facing Halal Certification Siska, Siska; Rahmi, Hanifah; Situmorang, Almawati
Indonesian Journal of Halal Research Vol. 2 No. 2 (2020): August
Publisher : UIN Sunan Gunung Djati Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15575/ijhar.v2i2.8281

Abstract

Indonesia is the largest Muslim population country in the world, so the market demand for halal products is enormous. However, in fact, there are not many business actors who submit and have halal certificates, especially in small and medium enterprises. This problem can be due to lack of information and sufficient understanding to apply for a halal certificate. The aim of the research is to give technical guidance for preparing halal certification process. The manual method is used to provide training on the halal guarantee system for the preparation of the halal assurance system (HAS). The workshop began with a pre-test and then the presentation of halal assurance system material, the guidance on how to prepare and discussion. All the activities were done by online (WhatsApp group and zoom meeting). The training ended with the post-test to assess the improvement of knowledge of the. To analyze the difference, we used a paired T-test statistical method. The result of this research shows an increasing understanding of participants (p<0,05) through the comparison between before and after training. These activities conclude that the practice of technical guidance for facing halal certification is beneficial for small and medium enterprises in improving knowledge and capability of the halal certification process.
Co-Authors Agustian, Ifany Apriaji, Meta HANIFAH RAHMI Kori Yati Miftahul Janah, Miftahul Siska Siska Supandi Tashdiq Anwarulloh, Tashdiq Umoro, Ani Umoro, Ani Wahyu Hidayati