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All Journal Jurnal Ilmiah Teknik Mesin Biology, Medicine, & Natural Product Chemistry Jurnal Sisfotek Global
Teguh Sugiarto, Teguh
Lampung University
Biochemistry, Genetics & Molecular Biology Computer Science & IT Mechanical Engineering Medicine & Pharmacology Public Health

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Sistem Informasi Pengaduan dan Aspirasi Warga Sekolah Pada SMK Negeri 53 Jakarta Raharjo, Joko S. Dwi; Setiady, Teddy; Sugiarto, Teguh
JURNAL SISFOTEK GLOBAL Vol 10, No 1 (2020): JURNAL SISFOTEK GLOBAL
Publisher : STMIK Bina Sarana Global

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.38101/sisfotek.v10i1.275

Abstract

Abstrak— Sistem informasi menjawab perkembangan kebutuhan masyarakat dalam hal pelayanan pada bidang pendidikan. Pengaduan dan Aspirasi pada instansi pendidikan sangat penting untuk kemajuan dan ketertiban suatu lembaga sekolah. Peneliti mengembangkan sistem informasi dengan memanfaatkan satu sistem yang telah berjalan namun masih belum maksimal dengan membuat se            buah media untuk menangani Pengaduan dan Aspirasi Warga Sekolah. Sistem yang dihasilkan dari pengembangan ini memiliki keunggulan pengaduan dan penyampaian aspirasi yang terkategori seperti kesiswaan, kegiatan belajar mengajar dan sarana prasarana akan cepat dan tepat ditangani oleh pihak terkait dengan terhubung oleh internet sehingga dapat diakses kapanpun dan dimanapun serta mudah digunakan.
ANALISIS UJI KETAHANAN LELAH BAJA KARBON SEDANG AISI 1045 DENGAN HEAT TREATMENT (QUENCHING) DENGAN MENGGUNAKAN ALAT ROTARY BENDING Sugiarto, Teguh; Zulhanif, .; Sugiyanto, .
Jurnal Ilmiah Teknik Mesin FEMA Vol. 1 No. 3 (2013)
Publisher : FT UNILA

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Abstract

Fatigue is the one of the main cause from of the material failure. The main of cause failure 90 % caused fatigue.   Fatigue is material sructure process changes that is caused by repeatly load (stress or shear) in a long period of time so it occured crack or break. The reason of this research is to analyze of the fatigue strength medium carbon steel type AISI 1045 with variaton of shaft rotation on rotary bending machine. Fatigue test applied on medium carbon steel  type AISI 1045 without heat treatment. This research was conducted with variation of shaft rotation 2880 rpm and continued with load variation 20%, 30%, 40%, 50% and 60 % from material UTS. Specimen that used according ASTM E466 spesimen made by lathe machine. Fatigue test is using by rotary bending machine type fatigue test machine.Keywords:Fatigue test, rotary bending, medium carbon steel  AISI 1045.
Unveiling the Synergistic Multi-Target Antidiabetic Mechanism of Indonesian Scientific Jamu Formulation: A Computational Study Prasetiyo, Andri; Sugiarto, Teguh; Mulatsari, Esti; Mumpuni, Esti; Junky, Vandrico; Adipura, Fadhiil Muhammad Dzaki; Nainggolan, Claudya Fransiska Pratamauli
Biology, Medicine, & Natural Product Chemistry Vol 15, No 1 (2026)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2026.151.357-364

Abstract

This study aimed to evaluate the multi-target antidiabetic potential of bioactive compounds within the Indonesian Scientific Jamu formulation (consisting of Andrographis paniculata, Curcuma xanthorrhiza, Cinnamomum burmannii, and Syzygium polyanthum) via an in silico approach targeting PPAR-gamma, DPP-4, AKR1C3, and SGLT2. Molecular docking simulations were performed to screen 238 bioactive compounds using Molegro Virtual Docker to predict binding affinities, while ADMET properties were analyzed using pkCSM. The simulation revealed that Cinnamoside, Procyanidin B2, Bisandrographolide B, and Gemin D exhibited the lowest energy on their respective targets. Significantly, 2,6-Di-O-galloyl-beta-D-glucose emerged as a superior multi-target compound, consistently outperforming standard drugs (Pioglitazone, Teneligliptin, Glimepiride, and Empagliflozin) against all four receptors. It was concluded that the formulation contained potent compounds acting through a synergistic multi-target mechanism, specifically 2,6-Di-O-galloyl-?-D-glucose, providing a molecular rationale for the formulation’s clinical efficacy.
Co-Authors . Sugiyanto . Zulhanif Adipura, Fadhiil Muhammad Dzaki Andri Prasetiyo Esti Mumpuni, Esti Joko S Dwi Raharjo Junky, Vandrico Mulatsari, Esti Nainggolan, Claudya Fransiska Pratamauli TEDDY SETIADY