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All Journal Jurnal Ar Ro'is Mandalika (Armada) Jurnal of Syiah Kuala Dentistry Society
Irma Ervina, Irma
Department of Periodontics, Faculty of Dentistry, Universitas Indonesia, Jakarta 10430
Religion Dentistry Education Languange, Linguistic, Communication & Media Mathematics Medicine & Pharmacology

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The Effectiveness of Salvadora persica (miswak) on Periodontal Health, Literature Review Ersa, Savana; Ervina, Irma
Journal of Syiah Kuala Dentistry Society Vol 9, No 1 (2024): June 2024
Publisher : Dentistry Faculty

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jds.v9i1.36558

Abstract

Periodontal disease is a global prevalent burden on well-being and health-related quality of life. Adequate plaque control on a daily routine basis is the most critical thing to achieve periodontal health. Using toothbrushes in combination with dentifrices is one of the most common methods of oral hygiene maintenance. However, natural chewing sticks such as Salvadora persica are still used in many developing countries due to their low cost and religious background. Salvadora persica displays precious biotherapeutics capacity for antimicrobial, antiviral, antioxidant, and anti-inflammatory effects. Recently, a lot of Salvadora persica extract has been found in dentifrices, mouthwash, chewing Gum, and even local delivery drugs such as periodontal chips, which are still in the research stage.The present review aims to summarize the evidence of various pharmacological and therapeutic aspects of the effectiveness of Salvadora persica in promoting periodontal health and the treatment of periodontal disease.
Antibacterial Activity of Toothpaste Containing Sunflower Seed Extract against Staphylococcus aureus In Vitro Putri Sianipar, Agnes Raiwana; Syahputra, Armia; Ervina, Irma; Amalia, Martina
Jurnal Ar Ro'is Mandalika (Armada) Vol. 6 No. 3 (2026): JURNAL AR RO'IS MANDALIKA (ARMADA)
Publisher : Institut Penelitian dan Pengembangan Mandalika Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59613/armada.v6i3.6232

Abstract

The increasing prevalence of oral bacterial infections and growing concerns regarding the long-term use of synthetic antibacterial agents have encouraged the exploration of natural alternatives in oral care products. This study aimed to evaluate the antibacterial effectiveness of toothpaste containing sunflower seed extract (Helianthus annuus Linn.) against Staphylococcus aureus ATCC® 29213 in vitro. Sunflower seeds were extracted using maceration, followed by phytochemical screening to identify bioactive secondary metabolites. The extract was formulated into toothpaste at concentrations of 2.5%, 5%, and 10%. A commercial antibacterial toothpaste (Siwak-F) was used as a positive control, while toothpaste base without antibacterial agents served as a negative control. Physicochemical characteristics of the formulations, including organoleptic properties, homogeneity, pH, spreadability, and viscosity, were evaluated to ensure formulation quality. Antibacterial activity was assessed using the agar well diffusion method on Mueller–Hinton Agar, and inhibition zone diameters were measured after 24 hours of incubation at 37°C. Statistical analysis was performed using the Kruskal–Wallis test followed by the Mann–Whitney post hoc test. The results demonstrated a concentration-dependent increase in antibacterial activity. Toothpaste containing 10% sunflower seed extract produced the largest inhibition zone and exhibited antibacterial activity comparable to the positive control, with no statistically significant difference. Lower concentrations (2.5% and 5%) also showed significant antibacterial effects compared to the negative control. These findings indicate that sunflower seed extract-based toothpaste has strong potential as a natural antibacterial dentifrice and may serve as a safer alternative to synthetic antibacterial agents in oral healthcare.
Co-Authors Amalia, Martina Armia Syahputra Ersa, Savana Putri Sianipar, Agnes Raiwana