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All Journal Indonesian Journal of Tropical and Infectious Disease Jurnal Inovasi dan Pengembangan Hasil Pengabdian Masyarakat
Jayanti Putri, Jayanti
Department of Clinical Microbiology, Dr. Soetomo General Hospital - Faculty of Medicine Universitas Airlangga, Surabaya
Religion Earth & Planetary Sciences Education Health Professions Languange, Linguistic, Communication & Media Medicine & Pharmacology Public Health Social Sciences Other

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THE ANTI-TB DRUG SENSITIVITY OF Mycobacterium tuberculosis FROM CEREBROSPINAL FLUID AND BONE TISSUE BIOPSY SPECIMENS OF PATIENTS SUSPECTED TUBERCULOUS MENINGITIS AND SPINAL TB IN Dr SOETOMO HOSPITAL INDONESIA Mertaniasih, Ni Made; Kusumaningrum, Deby; Koendhori, Eko Budi; Harijono, Sugeng; Arky, Catur Endra; Putri, Jayanti; Urifah, Hanik
Indonesian Journal of Tropical and Infectious Disease Vol 5, No 3 (2014)
Publisher : Institute of Topical Disease

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Tuberculous meningitis (TBM) is an infection of meningens which potentially life threatening with significant morbidity and mortality. Spinal TB has the same problem with TBM, infection in bone and joint, the delayed diagnosis worsens the prognosis. The rapid and accurate diagnosis plus promt adequate treatment is essential for the good outcome. The aim of this research is to study thefirst line drug sensitivity of Mycobacterium tuberculosis isolated from specimens of cerebrospinal fluid from suspected tuberculous meningitis patients and bone tissue biopsy from suspected spinal TB patients. The method of this research is TB Laboratory examination in Department of Clinical Microbiology – Dr. Soetomo General Hospital, Indonesia, using the gold standard liquid culture method MGIT 960 System (Becton Dickinson) and solid culture method with Lowenstein-Jensen medium. The specimens CSF from 50 TBM patients at January 2013 until May 2014. Positive isolate detection of Mycobacterium tuberculosis complex were 11 isolates (22%), which sensitivity 100% (11/11 isolates) to Rifampin (R), Pyrazinamide (Z), Ethambutol (E), and Streptomycin (S); one isolate resistant to Isoniazid, sensitivity to Isoniazid 90,90% (10/11); and received 21 specimens of bone tissue biopsy which positive 5 isolates(23%), all isolates sensitive 100% (5/5 isolates) to Rifampin and Pyrazinamide, and 1 isolates resistant to Isoniazid, Ethambutol, and Streptomycin, in which sensitivity 80% (4/5 isolates) to Isoniazid, Ethambutol, and Streptomycin. The conclusion of this research is positivity detection 22% of CSF specimens, and 23% of bone tissue biopsy were low. All isolates sensitive 100% to Rifampin and Pyrazinamide, and 80-90% sensitive to Isoniazid.
THE ANTI-TB DRUG SENSITIVITY OF Mycobacterium tuberculosis FROM CEREBROSPINAL FLUID AND BONE TISSUE BIOPSY SPECIMENS OF PATIENTS SUSPECTED TUBERCULOUS MENINGITIS AND SPINAL TB IN Dr SOETOMO HOSPITAL INDONESIA Mertaniasih, Ni Made; Kusumaningrum, Deby; Koendhori, Eko Budi; Harijono, Sugeng; Arky, Catur Endra; Putri, Jayanti; Urifah, Hanik
Indonesian Journal of Tropical and Infectious Disease Vol. 5 No. 3 (2014)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (152.009 KB) | DOI: 10.20473/ijtid.v5i3.236

Abstract

Tuberculous meningitis (TBM) is an infection of meningens which potentially life threatening with significant morbidity and mortality. Spinal TB has the same problem with TBM, infection in bone and joint, the delayed diagnosis worsens the prognosis. The rapid and accurate diagnosis plus promt adequate treatment is essential for the good outcome. The aim of this research is to study thefirst line drug sensitivity of Mycobacterium tuberculosis isolated from specimens of cerebrospinal fluid from suspected tuberculous meningitis patients and bone tissue biopsy from suspected spinal TB patients. The method of this research is TB Laboratory examination in Department of Clinical Microbiology – Dr. Soetomo General Hospital, Indonesia, using the gold standard liquid culture method MGIT 960 System (Becton Dickinson) and solid culture method with Lowenstein-Jensen medium. The specimens CSF from 50 TBM patients at January 2013 until May 2014. Positive isolate detection of Mycobacterium tuberculosis complex were 11 isolates (22%), which sensitivity 100% (11/11 isolates) to Rifampin (R), Pyrazinamide (Z), Ethambutol (E), and Streptomycin (S); one isolate resistant to Isoniazid, sensitivity to Isoniazid 90,90% (10/11); and received 21 specimens of bone tissue biopsy which positive 5 isolates(23%), all isolates sensitive 100% (5/5 isolates) to Rifampin and Pyrazinamide, and 1 isolates resistant to Isoniazid, Ethambutol, and Streptomycin, in which sensitivity 80% (4/5 isolates) to Isoniazid, Ethambutol, and Streptomycin. The conclusion of this research is positivity detection 22% of CSF specimens, and 23% of bone tissue biopsy were low. All isolates sensitive 100% to Rifampin and Pyrazinamide, and 80-90% sensitive to Isoniazid.
Project P5: How is assistance in implementing the independent curriculum in elementary schools? Utaminingsih, Sri; Putri, Jayanti; Rondli, Wawan Shokib; Fathurohman, Irfai; Hariyadi, Ahmad
Jurnal Inovasi dan Pengembangan Hasil Pengabdian Masyarakat Vol. 1 No. 2 (2023): Jurnal Inovasi dan Pengembangan Hasil Pengabdian Masyarakat (December)
Publisher : CV. BImbingan Belajar Assyfa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61650/jip-dimas.v1i2.229

Abstract

Schools in SD 4 Gulang, Kudus Regency, currently need help in implementing the independent curriculum due to instructors' difficulties in setting themes, selecting sub-themes, determining activities, compiling project modules, and assessing their implementation. This mentoring method consists of seven in-person and online meetings. The results of the assistance demonstrated that SD 4 Gulang was able to modify the project module to strengthen the Pancasila profile of grade 1 students. Project 1's theme and topic were Entrepreneurship and Entrepreneurship Processing Waste, while Project 2's theme was Local Wisdom. My Snacks, My Culture is the topic. Each project's activity phase is divided into the introduction, contextualization, follow-up action, and reflection stages, respectively. Class IV project implementation for Project 1 has the theme of entrepreneurship, with the topic of turning trash into a blessing, and Project 2 has the theme of local knowledge, with the topic of consuming Kudus-style snacks. Strengthening the implementation of the Pancasila Student Profile The project activities at SD 4 Gulang are conducted in accordance with the prepared activity flow, and the assessment is based on the dimensions, elements, and sub-elements that have been determined. Teachers and students' comprehension and proficiency in implementing the Pancasila Student Profile Strengthening increased following mentoring. The Project
Co-Authors Ahmad Hariyadi, Ahmad Catur Endra Arky, Catur Endra Deby Kusumaningrum Eko Budi Koendhori, Eko Budi Hanik Urifah, Hanik Irfai Fathurohman, Irfai Ni Made Mertaniasih Sri Utaminingsih Sugeng Harijono, Sugeng Wawan Shokib Rondli