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All Journal Jurnal Dedikasi Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Pharmaciana: Jurnal Kefarmasian JPsd ( Jurnal Pendidikan Sekolah Dasar ) Jurnal Surya Medika Jurnal Kesehatan Tambusai Pharmaceutical Sciences and Research (PSR) Jurnal Kefarmasian Indonesia
Dian Ermawati
Universitas Muhammadiyah Malang
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Dentistry Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health

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Development microemulsion formulation combination of citronella and red ginger essential oil Chasanah, Uswatun; Wardhani, Ellen Kusuma; Ermawati, Dian
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 8 No. 2 (2023)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v8i2.35039

Abstract

Acne vulgaris is a skin health problem. Citronella oil contains citronellal, geraniol, geranial, β-citronellol, and neral, which have antibacterial properties. Meanwhile, red ginger oil contains gingerol, which has anti-inflammatory properties. These two ingredients are suitable for treating acne vulgaris. The aim of this study are to develop microemulsion formulation combination of citronella and red ginger essential oil. In this experimental study, a microemulsion combination of citronella essential oil and red ginger essential oil was made using Tween 80 as a surfactant and Transcutol® as a co-surfactant, with variations of S-mix (surfactant:cosurfactant) of 3:3, 4:2, and 4.5:1.5 ratios. As an oil carrier, isopropyl myristate is used. The microemulsions are formulated using a titration method. The microemulsion was then tested for characteristics and stability. The results show that the most optimal microemulsion formula was obtained with an S-mix ratio of 4:2 with a globule size of 21.64 nm, a Polydispersion Index of 0.15, and a zeta potential of -3.82. Its pH and viscosity meet the required specifications and are stable.
Characterisation and Antibacterial Activity of Green Tea Extract-Enriched Solid Goat’s Milk Soap Chasanah, Uswatun; Ermawati, Dian; Utami, Dwi Putri; Hayati, Angela Nora
Pharmaceutical Sciences and Research Vol. 9, No. 3
Publisher : UI Scholars Hub

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Abstract

Solid goat’s milk soap is organic and beneficial for the health and appearance of the skin. One of the components in green tea known to display antibacterial activities is epigallocatechin gallate (ECGC). In this study, the effects of solid goat’s milk soap containing 1%, 2%, and 4% green tea extract on the growth of Propionibacterium acnes, Staphylococcus aureus, and Staphylococcus epidermidis were examined. The soap was characterized for its organoleptic, pH, free fatty acid, alkalinity, water content, foam stability, and hardness. In addition, an in vitro antimicrobial test was performed utilising the well-diffusion method. The findings revealed that all the soap formulas matched the SNI 3533-2016 standards for water content, free fatty acid content, and free alkali content, and that they also had similar pH, foam stability, and hardness. The solid goat’s milk soap showed antibacterial activities against Propionibacterium acnes, Staphylococcus aureus, and Staphylococcus epidermidis, but the effect of the green tea extract on the soap did not increase these.
FORMULASI LOSION REPELAN KOMBINASI MINYAK KENANGA (2,5%, 5% DAN 7,5%) DAN MINYAK NILAM 1% (PENGUJIAN KARAKTERISTIK FISIKA KIMIA, STABILITAS DAN IRITASI) Hasanah, Uswatun; Chasanah, Uswatun; Ermawati, Dian
Jurnal Kesehatan Tambusai Vol. 6 No. 2 (2025): JUNI 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v6i2.44854

Abstract

Minyak kenanga dan minyak nilam merupakan minyak atsiri alami yang berpotensi sebagai antinyamuk. Losion antinyamuk merupakan salah satu bentuk sediaan yang dapat digunakan sebagai pelindung dari gigitan nyamuk.Tujuan penelitian ini untuk mengetahui karakteristik fisika kimia, stabilitas dan iritasi sediaan losion antinyamuk pada 3 formula yaitu F1 (Minyak kenanga 2,5% dan Minyak Nilam 1%), F2 (Minyak Kenanga 5% dan Minyak Nilam 1%), dan F3 (Minyak Kenanga 7,5% dan Nilam 1%). Metode penelitian eksperimental dengan membandingkan ketiga kombinasi losion minyak kenanga dan minyak nilam dan dilakukan uji organoleptis, homogenitas, tipe emulsi, ukuran partikel, daya sebar, viskositas, pH, dan stabilitas dengan metode cycling test serta uji iritasi sediaan dengan metode (Hen’s Egg Test - Chlorioallantoic Membrane) HET-CAM. Sediaan losion repelan pada ketiga formula memiliki karakteristik fisik kimia sesuai dengan persyaratan. Hasil uji stabilitas metode cycling test memiliki stabilitas baik serta uji iritasi sedian tidak menunjukkan adanya iritasi terhadap CAM. Seluruh formulasi sediaan losion repelan kombinasi minyak atsiri kenanga dan nilam, berdasarkan hasil pengujian fisika kimia, stabilitas dan iritasi sesuai persyaratan mutu sediaan.
Co-Authors Amalia, Nova Andani, Herika Juli Cahyani, Pradina Zustrian Chasanah, Uswatun Engrid Juni Astuti Hayati, Angela Nora Herika Juli Andani Hidajah Rachmawati Ika Ratna Hidayati Juniarty, Amelya Khalda Nisrina Mahardhika, Chandra Leony Nisrina, Khalda Risqika Yulia Tantri Paramawidhita Shahnaz, Ifa Uswatun Chasanah Uswatun Hasanah Utami, Dwi Putri Vini Nurbaiti Wardhani, Ellen Kusuma