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All Journal Jurnal Kedokteran Komunitas (Journal of Community Medicine)
M. Zainul Fikri
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Biochemistry, Genetics & Molecular Biology Education Immunology & microbiology Medicine & Pharmacology Public Health

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Efek Ekstrak Etanol Bawang Lanang (Aliium sativum L.) terhadap Paralisis dan Kematian Cacing Dewasa Ascaris suum, Goeze M. Zainul Fikri; Reza Hakim; Dini Sri Damayanti
Jurnal Kedokteran Komunitas Vol 8, No 2 (2020)
Publisher : Jurnal Kedokteran Komunitas (Journal of Community Medicine)

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Abstract

Introduction: Single Garlic (Allium satuvum L.) can be an alternative cure for the Ascariasis disease because it has compound anti-helmintik like saponin, allicin, and flavonoid that can kill a worm contained in the human body.Method: This research uses the in vitro experimental laboratory. In the sample collection Ascaris suum , goeze used method of random purposive sampling. Ascaris suum , goeze roundworm used in this study amounted to 28 tail included in 7 groups tube which each canister contains 4 worms. 7 groups tube consist of the negative control group (NaCl 0.9 %), 5 group consist single garlic ethanol extract (0.5 % , 1 % , 2 % , 4 % , 8 % ) , and positive control group (pirantel pamoat 5 mg / ml).Result: The results obtained in the linear regression show significant impact (P>0,05) with the required PC50 0,81% to make the paralysis 50% of the total number of worms and it takes concentration Single Garlic extract LC50 2,09% to make the death of 50% of the total number of worms.Conclusion: Extract ethanol of Single Garlic is having an effect on anti-helmintik Ascaris suum, Goeze roundworms.Key Word: Single Garlic Extract, PC50 Paralysis, LC50 Death, Ascaris suum Goeze Adult Worm
Co-Authors Damayanti, Dini Sri Reza Hakim