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La Jumu, La
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Effectiveness of wamena pugima honey on incision wound healing: an experimental study Kismiyati; Jumu, La; Felle, Zeth Robert
MEDISAINS: Jurnal Ilmiah Ilmu-Ilmu Kesehatan Vol. 24 No. 1 (2026)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v24i1.30299

Abstract

Background: Honey contains bioactive compounds that may accelerate wound healing; however, its therapeutic effectiveness varies depending on botanical origin. Wamena Pugima honey, a local Papuan honey, is presumed to possess unique bioactive properties due to endemic flora, yet its efficacy in wound healing has not been scientifically evaluated. Objective: This study aimed to evaluate the effectiveness of Pugima honey on incision wound healing using a Swiss Webster mouse model. Methods: his experimental study employed a randomized controlled design involving 36 male Swiss Webster mice, randomly allocated into three groups (n = 12 per group): positive control 1 (C1, 3% oxytetracycline ointment), combination control (C2, oxytetracycline ointment plus Pugima honey), and treatment group (P1, Pugima honey). Phytochemical screening was conducted to identify bioactive compounds. Wound length was measured on Days 3, 7, 9, 13, and 14, and wound contraction percentage was calculated accordingly. Statistical analysis was performed using the Kruskal–Wallis test followed by Dunn’s post hoc test. Results: Phytochemical screening revealed the presence of flavonoids, phenols, tannins, and saponins, indicating potential anti-inflammatory and antibacterial properties. The Pugima honey group (P1) demonstrated significantly accelerated wound healing compared to both control groups, with shorter wound length observed as early as Day 3 (10.50 ± 1.83 mm vs. 14.00 ± 1.12 mm in C1; p = 0.001). Conclusions: Pugima honey significantly enhances incision wound healing, particularly during the early to intermediate phases, and shows potential as a natural therapeutic agent for wound management.
BEDA TINGKAT PENGETAHUAN SISWA KELAS XI SMA YAPIS BIAK SEBELUM DAN SETELAH EDUKASI KOMPLIKASI PENYAKIT SOSIAL TERHADAP KEJADIAN HIV/AIDS DI BIAK NUMFOR La Jumu
JURNAL KEPERAWATAN TROPIS PAPUA Vol 3, No 2 (2020)
Publisher : Poltekkes Kemenkes Jayapura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47539/jktp.v3i2.106

Abstract

Edukasi komplikasi penyakit sosial terhadap kejadian HIV ADIS melalui siswa SMTA adalah merupakan upaya pencegahan dan pemberantasan penyakit sosial dan juga komplikasinya terhadap kejadaian HIV AIDS, agar generasi muda siswa SMTA mengetahui secara dini, cara pencegahan kedua penyakit tersebut karena kondisinya, telah meresahkan masyarakat dengan bentuk kejadian berupa kesakitan dan kematian, makin hari, makin tahun semakin bertambah dan menimpah seluruh lapisan masyarakat dari bayi balita sampai kakek nenek. Penelitian ini bertujuan untuk menganalisis perbedaan sebelum dan setelah edukasi penyakit sosial terhadap kejadian HIV AIDS dengan, 36 responden., dianalisis berdasarkan tingkat pengetahuan dengan cara mengisi soal pretest dan post test. Penelitian menggunakan metode analitik kuantitatif dengan pendekatan cross sectional, pengambilan sampel secara Propotive sampling pada populasi 50 siswa dan teknik penetapan responden secara acak , didapat 36 responden, dengan jenis uji statistik Wilcoxon. Nilai Wilcoxon Signed Ranks Test di Asymp Sig. (2-tailed) adalah (Z hitung P = 0,000) kurang dari (Z tabel P value < 0,05). Hasil penelitian menunjukkan terdapat perbedaan yang signifikan (Z hitung P = 0,000) sebelum dan setelah edukasi komplikasi penyakit sosial terhadap kejadian HIV AIDS pada siswa SMTA, jadi saran edukasi komplikasi penyakit sosial dengan komplikasi HIV AIDS dapat dikembangkan terus dengan harapan remaja dapat mengetahui secara dini cara mencegah diri dari penyakit sosial dan komplikasinya terhadap HIV AIDS.
Co-Authors Afzal, Ridha Arief, Dharmawan Aswar, Sophian Dharmawan Arief Edison Kabak Febry Istyanto Felle, Zeth Robert Halitopo, Yoel Hardy, Syaifoel Isak Jurun Hans Tukayo Kismiyati Miranti Miranti Nouvy Helda Warouw Paula Krisanty Ridha Afzal Sophian Aswar Sugeng Riyadi Sugeng Riyadi Sukatemin Sukatemin Sukatemin Sukatemin, Sukatemin Syaifoel Hardy Syaifoel Hardy Syaifoel Hardy