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Artha Yuliana Sianipar
Universitas Sari Mutiara Indonesia
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology

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UJI ANTIBAKTERI EKSTRAK ETANOL DAUN BIDARA ARAB (Ziziphus jujuba Mill) TERHADAP BAKTERI S. aureus DAN S. epidermidis: UJI ANTIBAKTERI EKSTRAK ETANOL DAUN BIDARA ARAB (Ziziphus jujuba Mill) TERHADAP BAKTERI S. aureus DAN S. epidermidis Eva Diansari Marbun; Alfi Sapitri; Artha Yuliana Sianipar
FORTE JOURNAL Vol 2 No 1 (2022): Vol. 2 No. 1 (2022) : Edisi Januari
Publisher : Universitas Haji Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51771/fj.v2i1.200

Abstract

Bidara arab (Ziziphus jujuba Mill) merupakan tumbuhan semak atau pohon  berduri yang digunakan sebagai obat tradisional. Tujuan penelitian ini adalah untuk mengetahui aktivitas antibakteri EEDBA (Ziziphus jujuba Mill) terhadap bakteri S. aureus dan S.epidermidis. Pembuatan EEDBA dilakukan dengan cara perkolasi menggunakan etanol 96%. Pengujian aktivitas antibakteri dilakukan dengan cara difusi menggunakan kertas cakram (Uji Kirby-Bauer). Hasil penelitian EEDBA sebagai antibakteri berdasarkan parameter luas zona hambat terhadap bakteri S. aureus dengan konsentrasi 2% rata-rata yaitu 11,2 mm, 3% yaitu 12,2 mm, 4% yaitu 13,4 mm, 5% yaitu 16,0 mm. Sedangkan bakteri S.epidermidis pada konsentrasi 2 % rata-rata yaitu 12,0 mm, 3% yaitu 14,6 mm, 4% yaitu 15,8 mm, 5% yaitu 16,6 mm serta diameter kontrol positif keduanya rata-rata yaitu 27,2 mm. Berdasarkan analisis statistik pada anova menunjukkan EEDBA (Ziziphus jujuba Mill) bisa menghambat pertumbuhan bakteri S. aureus dan S.epidermidis dengan sangat nyata (Fh>Ft;α=0,05).
EVALUASI RASIONALITAS PENGGUNAAN ANTIBIOTIK ISPA PADA PASIEN RAWAT JALAN DI PUSKESMAS KECAMATAN GUNUNG SITOLI Artha Yuliana Sianipar; Grace Anastasia Ginting; Yosefin Hellen
FORTE JOURNAL Vol 2 No 2 (2022): Edisi Juli 2022
Publisher : Universitas Haji Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51771/fj.v2i2.352

Abstract

URTI (Upper Respiratory Tract Infection) is a major disease in children in outpatient installation. Antibiotics are the most widely used class of drugs to treat infections. Antibiotics must be used rationally. Because the bad impact that occurs is the emergence of bacterial resistance. This study aims to obtain an overview of the rationality of the use of antibiotics in URTI patients, especially in children aged 5 to 11 years. The method used is a retrospective descriptive method, using medical record cards and prescription sheets for patients diagnosed with URTI and receiving antibiotics at the Gunungsitoli District Health Center during the period January to December 2020. Sampling used the purposive sampling method. Data that met the inclusion criteria were children aged 5-11 years and receiving antibiotic therapy. Then a table is made which includes the patient's identity, diagnosis, antibiotics, and the dose used. Then presented in the form of percentages, average values ​​and tables. The results showed that of the 64 patients who suffered the most URTI by age were patients aged 5 years (26.56%), the antibiotic group that was most often prescribed was the penicillin group, namely amoxicillin. (54.69%). Evaluation of rational use of antibiotics based on the 2011 Ministry of Health guidelines includes the right patient criteria (100%), right indication (100%), right frequency (100%), right drug (100%), right duration (98.44%), and right dose (93.75%).
Co-Authors Alfi Sapitri Grace Anastasia Ginting Marbun, Eva Diansari Yosefin Hellen