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Comparative Study of FT-IR Profiles Preparation of Nano-Hydrogel Combination of Soursop Extract and Zinc Urmatul Waznah; Achmad Vandian; Eko Mugiyanto; Nuniek Nizmah Fajriyah
Prosiding University Research Colloquium Proceeding of The 15th University Research Colloquium 2022: Bidang MIPA dan Kesehatan
Publisher : Konsorsium Lembaga Penelitian dan Pengabdian kepada Masyarakat Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

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Abstract

Nanoparticles delivery system of of herbal preparations and their combinations has received more attention from scientists recently. This combination might lead to chemical reactions among the added constituents. This study aims to compare the FT-IR profile of Carbopol-940 base before and after the addition of soursop extract and zinc oxide nanoparticle. The preparation is made by mixing the base with Annona muricata nano-extracts and nano-zinc. Extraction was carried out by cold maceration of A. muricata leaves in ethanol and then convert into nanoparticles with the assisting of Chitosan biopolymer by ionic gelation method. Nano-zinc is formulated by precipitating zinc acetate by sodium hydroxide. The two nano-formulas were then mixed up into the Carbopol-940 gel matrix. The results show a shift in the profile of Carbopol-940 at a wavelength of 1500 nm to 1700 nm. From the results, it can be seen that there is no difference in the physical characteristics of the base with the addition of the two nano active ingredients. Further research needs to be done to confirm this finding.
Paket Edukasi dan Deteksi Dini Meningkatkan Perilaku Perawatan Kaki Diabetisi di Puskesmas Kabupaten Pekalongan Nuniek Nizmah Fajriyah; Nurul Aktifah; Eko Mugiyanto
Gaster Vol 18 No 1 (2020): FEBRUARI
Publisher : P3M Universitas 'Aisyiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (317.184 KB) | DOI: 10.30787/gaster.v18i1.402

Abstract

Ulserasi pada tungkai bawah merupakan salah satu manifestasi penyakit diabetes melitus yaang disebabkan kerusakan pada jaringan di bawahnya, yang disebut kaki diabetik (KD). Deteksi dini KD sangat penting untuk perawatan kaki diabetes untuk meningkatkan kualitas hidup diabetisi. Tujuan dari penelitian ini menguji keefektifan Paket Edukasi Perawatan Kaki Diabetes (PEPKD) dan Deteksi Dini (DD) terhadap perilaku perawatan kaki diabetik Tipe 2. Desain penelitian ini adalah eksperimental semu dengan pre-test dan post-test. . Teknik pengambilan sampel menggunakan accidental sampling. Penelitian ini dilakukan di Puskesmas kabupaten Pekalongan. Analisis data menggunakan Wilcoxon Signed Rank Test. Hasil penelitian menunjukkan ada efek PEPKD terhadap perilaku perawatan kaki pasien dengan p = 0,001 (p <0,005). Perawat dapat melakukan deteksi dini keadaan pembuluh darah kaki diabetik, melalui observasi dan pemeriksaan langsung menggunakan teknik palpasi di arteri dorsal pedis, dan denyut tibialis posterior, pemeriksaan neuropatik dengan teknik Ipswich Touch Test.