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All Journal Nexus Biomedika Journal of Global Research in Public Health
Risky Pratiwi, Risky
Sebelas Maret University
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

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Pengaruh Pemberian Jus Stroberi (Fragaria x ananassa) Terhadap Kerusakan Histologis Sel Hepar Mencit yang Diinduksi Rhodamin B Pratiwi, Risky; Muthmainah, .; Sari, Yulia
Nexus Biomedika Vol 3, No 3 (2014): Nexus Biomedika
Publisher : Nexus Biomedika

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (13.862 KB)

Abstract

Background: Strawberry contains flavonoid, anthocyanin, ellagic acid and vitamin C that can protect the liver from free radicals. The aims of this research are to know the effect of strawberry juice and the increasing of its dose on the liver histological damage of mice caused by rhodamine B. Methods: This study was laboratory experimental research with the post-test only control group design. The laboratory animal used in this experiment was male Swiss webster mice with 2-3 months old and ± 20 grams of each weight. Twenty eight samples were divided into 4 groups (KKn, KP, KP1 and KP2), each group consisted of 7 mice. The sampling technique in this research was consecutive sampling. The normal control group (KKn) was given distilled water, while the exposure group (KP), the 1st treatment group (KP1), and 2nd treatment group (KP2) were given rhodamine B. The mice of KP1 and KP2 were given strawberry juice in dose 0.4 ml/20 gWt and 0.8 ml/20 gWt. These treatments were done for 16 days, then on the 17th day mice were killed with neck dislocation and their livers were made for preparation with paraffin block method and stained with HE. Liver cell histological damages were assessed based on quantifying necrotic cells of each 100 cells in the first zone and third zone. The data were analyzed using One-Way ANOVA test and Post Hoc LSD test (α = 0.05). Results: The data showed mean of necrotic cells in KKn, KP, KP1 and KP2 were 38.64 ± 2.56; 157.64 ± 2.87; 90.07 ± 2.70; and 68.93 ± 2.56, repeatedly. The results of One-Way ANOVA test showed p = 0.000. The results of LSD test showed significant difference between KKn-KP, KKn-KP1, KKn-KP2, KP-KP1, KP-KP2, and KP1-KP2 with p = 0.000 for each groups. Conclusion: Strawberry juice reduces mice’s liver cell histological damage caused by rhodamine B and the increasing dose of strawberry juice can reduce liver cell histological damage. Keywords: Strawberry juice, rhodamine B, liver cell histological damage  
RELATIONSHIP OF EATING PATTERN AND STRESS LEVELS WITH PRE ECLAMPSIA AMONG PREGNANT WOMEN AT CIKAMPEK HEALTH CENTRE IN 2021 Pratiwi, Risky; Anni Suciawati; Rukmaini
Journal of Global Research in Public Health Vol. 7 No. 1 (2022): June
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/jgrph.v7i1.527

Abstract

Preeclampsia is one of the complications in pregnancy that has criteria where gestational age is > 20 weeks, which is marked by swelling of the legs, and positive urine protein values ​​caused by various factors. Preliminary study results show that on average pregnant women with preeclampsia have unhealthy eating patterns and abnormal stress levels. This study aimed to determine the relationship between diet and stress levels with preeclampsia in pregnant women at the Cikampek Health Center in 2021. This study is a quantitative analytic study with a case control design. The sample in this study consisted of 96 people consisting of 48 samples of the preeclampsia group and 48 samples not experiencing preeclampsia with accidental sampling technique. Bivariate data analysis used Chi Square statistical test to determine the relationship between variables. Pregnant women with a healthy diet 53.1%, and stress levels with a mild category was 58.3%. Bivariate analysis revealed that there was a relationship between diet (p = 0.000) and stress levels (p = 0.004) with preeclampsia in pregnant women at the Cikampek Health Center in 2021. There was a significant relationship between diet and stress levels with preeclampsia in pregnant women at the Cikampek Health Centre in 2021 with a p-value <0.05. It is hoped that in carrying out the antenatal care service program, they can immediately carry out the making of a counseling schedule on how to calculate the nutrients consumed by the mother and the right amount of nutritional needs when pregnant women and stress management for pregnant women as an effort to prevent the occurrence of preeclampsia.
Co-Authors . Muthmainah Anni Suciawati Rukmaini Tamaulina Br Sembiring