Shofa Nur Fauzah
Faculty of Medicine, Universitas Swadaya Gunung Jati, Cirebon, Indonesia

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IMPACT OF OBESITY AND DIABETES MELLITUS TYPE II WITH INCIDENCE OF HYPERTENSION IN AGE 45-65 YEARS OLD Tiara Syamsa Noor Wildania; Shofa Nur Fauzah; Dini Sapardini Warsodoedi
Proceedings of the International Conference on Applied Science and Health No. 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

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Background: Hypertension is one of the main causes of mortality and morbidity in Indonesia. Hypertension is also the third biggest risk factor for early deaths. Several previous researches have shown that obesity and diabetes mellitus type II (DM type II) are the factors in the occurrence of hypertension. Previous research did not include the stage of obesity and DM type II, by this reason the research was aimed to analyze the correlation between the stage of obesity and stage of DM type II withhypertension. Methodology: This research used observational analytic with cross-sectional design. This study involved 161 patients who were selected by consecutive sampling method. The inclusion criteria of the sample were aged 45-60 years old, obese, and have been diagnosed of DM type II and hypertension in Waled Regional General Hospital. Results: The result revealed that stage of obesity and stage of DM type II were significantly associated with hypertension (p<001, p<01, respectively). Other variables that also significantly associated with hypertension were age and gender. Conclusion: There was the strong correlation between stage of obesity and hypertension. Public health policy maker may promote to prevent the obesity in order to decrease the incidence of hypertension. Keywords: Obesity, DM type II, Hypertension
COMPARISON OF EFFECTIVENESS BETWEEN CELERY JUICE (Apium graveolens L.) AND 2% MICONAZOLE TOWARDS THE GROWTH OF Malassezia furfur Ronaa Hammada; Witri Pratiwi; Shofa Nur Fauzah; Donny Nauphar; Amanah Amanah
Proceedings of the International Conference on Applied Science and Health No. 3 (2018)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

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Introduction: Pityriasis versicolor is caused by the fungi Malassezia furfur with a worldwide prevalence of 50%, including tropical countries, second only to dermatitis in Indonesia. Pityriasis versicolor is difficult to treat and requires long-term treatment. The disease has high recurrence risk and may cause drug resistance. 2% Miconazole is known to have long-term side effects; therefore, alternative treatment is needed. Several studies suggested that celery (Apium graveolens L.) contains active substances with anti-fungal properties. This paper aims to investigate the comparison of effectiveness between celery juice and 2% Miconazole towards the growth of Malassezia furfur. Methods: This is an in-vitro experimental study with post-test only control group design. The subjects were split into 5 groups which were given celery juice in 10% DMSO with the concentration of 10%, 20%, 30%, 40%, and 50%. A negative control group was given only 10% DMSO and the positive control group was given 2% Miconazole. The data were then analyzed using Kruskall-Wallis followed by Mann-Whitney test. Results: The Kruskall-Wallis test showed all concentration of celery juice had antifungal effect with p=0.000 (p<0.05) and were effective in inhibiting the growth of Malassezia furfur. The Mann-Whitney test showed that the 50% celery concentration was as effective as 2% Miconazole in inhibiting the growth of Malassezia furfur (p=0.495). Conclusion: Celery juice (Apium graveolens L.) was effective in inhibiting the growth of Malassezia furfur with 50% concentration as the most effective concentration.