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All Journal The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
Yudi Wahyudi
Department of Internal Medicine, Faculty of Medicine, Universitas Padjajaran/Hasan Sadikin General Hospital, Bandung
Medicine & Pharmacology

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Relationship between Gastroesophageal Reflux Disease Questionnaire (GERD-Q) Score and Reflux Oesophagitis in Gastroesophageal Reflux Disease (GERD) Suspected Patients in Bandung Dosmer Oloan Simarmata; Yudi Wahyudi; Muhammad Begawan Bestari; Rudi Supriadi
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 20, No 3 (2019): VOLUME 20, NUMBER 3, December 2019
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (180.274 KB) | DOI: 10.24871/2032019154-160

Abstract

Background: Gastroesophageal reflux disease is a disease with heterogen symptoms, with no gold standard available to diagnose this condition. Questionnaire is a diagnostic tool that may enable an objective symptom assessment. GERD-Q questionnaire consist of 6 components of questions, formed from 4 various components of reflux symptoms (positive predictors of GERD) and 2 as negative predictors of GERD. This study aimed to observe the relationship between GERD-Q score and reflux oesophagitis in GERD suspected patients.Method: This study was an analytic cross-sectional study, conducted in March to July 2019. Study participants were patients visiting the Endoscopy Unit in Hasan Sadikin Hospital, Cibabat District General Hospital, and Al Islam General Hospital, who were then evaluated using GERD-Q and later underwent endoscopy examination. The severity of reflux oesophagitis observed through endoscopy was evaluated using the Los Angeles classification. Endoscopy readings was performed by one experienced doctor.Results: Thirty-six patients were examined; 17 (47.2%) patients suffered from reflux oesophagitis, including 13 cases with grade A (76.5%) and 4 cases with grade B (23.5%). There were no cases with grade C or grade D was found. Patients who suffered from reflux oesophagitis with GERD-Q score ≥ 8 were 15 patients (65.2%) and GERD-Q score 8 were 2 patients (15.4%). Chi Square test analysis with confidence interval of 95% revealed p = 0.004 (p 0.05). Biserial point correlation coefficient was 0.643 with p 0.001.Conclusion: There was a strong relationship between GERD-Q score and reflux oesophagitis. The higher the GERD-Q score, the higher the possibility to suffer from reflux oesophagitis.
Primary Biliary Cirrhosis Irvan Nugraha; Guntur Darmawan; Emmy Hermiyanti Pranggono; Yudi Wahyudi; Nenny Agustanti; Dolvy Girawan; Begawan Bestari
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 19, No 3 (2018): VOLUME 19, NUMBER 3, December 2018
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (308.295 KB) | DOI: 10.24871/1932018195-200

Abstract

Primary biliary cirrhosis (PBC) is an inflammatory disease or chronic liver inflammation, with slow progressive characteristic and is an unknown cholestatic liver disease and commonly happen in middle-aged women. The incidence of PBC is 0.03 – 5.8 per 100,000 people per year, prevalence of 1.91-40.2 per 100,000 people and continues to increase. Based on the American Association for Study of Liver Disease criteria, the diagnosis of PBC is made in the presence of two out of three criteria, which are increase of alkaline phosphatase, positive antimitochondrial antibodies (AMA), and histopathology examination.We reported a case which is very rarely found; a 47-year-old women with the chief complaints of decrease consciousness and jaundice. In physical examination, there were anaemic conjunctiva, icteric sclera, hepatosplenomegaly, palmar erythema, and liver nails. In the patient, there was no evidence of obstruction in imaging with two-fold increase of alkaline phosphatase and positive AMA test. Patient was hospitalised to slow down the progression of the disease and to overcome the signs (e.g. pruritus, osteoporosis and sicca syndrome).
Co-Authors Begawan Bestari Dolvy Girawan Dosmer Oloan Simarmata Emmy Hermiyanti Pranggono Guntur Darmawan Irvan Nugraha Muhammad Begawan Bestari Nenny Agustanti Rudi Supriadi