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All Journal International Journal of Integrated Health Sciences Althea Medical Journal Folia Medica Indonesiana The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
Emmy Hermiyanti Pranggono
Department Of Internal Medicine, Faculty Of Medicine, Universitas Padjajaran/Hasan Sadikin General Hospital, Bandung
Health Professions Medicine & Pharmacology Other

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Characteristics of Asthma Patients Seeking Care at West Java’s Top Referral Hospital, Indonesia Yudistira, Juan Achmad; Pranggono, Emmy Hermiyanti; Tjandrawati, Anna; Sudjana, Primal
Althea Medical Journal Vol 4, No 1 (2017)
Publisher : Althea Medical Journal

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Abstract

Background: The increasing incidence of asthma in many countries in recent decades makes asthma a global health problem. The aim of the study was to determine the characteristics of asthma patients at the Respirology Outpatient Clinic of Dr. Hasan Sadikin General Hospital as West Java’s Top referral hospital. Methods: The study used a cross-sectional design. The study population was the medical record data of asthma patients at the Respirology Outpatient Clinic during June 2012–June 2013. There were 1,591 patient’s medical records at the Respirology Outpatient Clinic of Dr. Hasan Sadikin General Hospital Bandung in that period and 140 medical records were diagnosed with asthma. Seventy medical records were excluded because of inadequate data and 70 medical records were the sample of this study. The collected data were presented using percentage. Results: Seventy percent of the cases were female. From these cases 34% of patients   were aged 51–60 years. The partially controlled type was the most frequent type of asthma (62%). The most common sign and symptom was shortness of breath (86%). The most common drug used was Beta 2 agonist drugs (90%).Conclusions: The characteristic of asthma is that the patients are mostly female. Mostly the patients were in the age range of 51–60 years. The partially controlled type is the most frequent type of asthma. Shortness of breath is the most common clinical manifestation in asthma. Beta 2 agonist is the most used drug for asthma. [AMJ.2017;4(1):78–82]DOI: 10.15850/amj.v4n1.1025
Clinical Characteristics and Side Effects of Multidrug Resistant Tuberculosis Therapy at Top Referral Hospital West Java Indonesia Rahmawati, Rika Nurlaily; Pranggono, Emmy Hermiyanti; Ruslami, Rovina
Althea Medical Journal Vol 3, No 4 (2016)
Publisher : Althea Medical Journal

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Background: The efficacy of multidrug resistant tuberculosis (MDR TB) therapy is still being questioned. It has lesser quality, longer duration therapy and high toxicity level. This study was conducted to identify clinical characteristics and side effect of MDR TB therapy at Dr. Hasan Sadikin General Hospital, Bandung, Indonesia as the top referral hospital in West Java. Methods: A retrospective descriptive study was performed to 142 medical records of MDR TB inpatient and outpatient at Dr. Hasan Sadikin General Hospital from January 2012–July 2013. Data was collected on October–November 2013. Data about clinical characteristics and side effects of MDR TB therapy were collected and was analyzed in the form of percentage.Results: From 142 patients, 96% had history of tuberculosis therapy. Eighty (56%) of them had positive acid fast bacilli (AFB) sputum that still remained after 5th month or more with category 2. Seventy (49%) patients used combination of pyrazinamide, capreomycin, levofloxacin, ethionamide and cycloserine (Pz-Cm-Lfx-Eto-Cs). All patients experienced side effects during therapy and the majority of them (91%) had gastroenteropathy and rheumatism. Tentamen suicide was detected in one patient. Conclusions: The MDR TB patients had history of tuberculosis therapy. The majority of patients used combination of Pz-Cm-Lfx-Eto-Cs. All patients experienced side effects during MDR TB therapy. [AMJ.2016;3(4):526–32]
Clinical Characteristics and Side Effects of Multidrug Resistant Tuberculosis Therapy at Top Referral Hospital West Java Indonesia Rika Nurlaily Rahmawati; Emmy Hermiyanti Pranggono; Rovina Ruslami
Althea Medical Journal Vol 3, No 4 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (246.776 KB)

Abstract

Background: The efficacy of multidrug resistant tuberculosis (MDR TB) therapy is still being questioned. It has lesser quality, longer duration therapy and high toxicity level. This study was conducted to identify clinical characteristics and side effect of MDR TB therapy at Dr. Hasan Sadikin General Hospital, Bandung, Indonesia as the top referral hospital in West Java. Methods: A retrospective descriptive study was performed to 142 medical records of MDR TB inpatient and outpatient at Dr. Hasan Sadikin General Hospital from January 2012–July 2013. Data was collected on October–November 2013. Data about clinical characteristics and side effects of MDR TB therapy were collected and was analyzed in the form of percentage.Results: From 142 patients, 96% had history of tuberculosis therapy. Eighty (56%) of them had positive acid fast bacilli (AFB) sputum that still remained after 5th month or more with category 2. Seventy (49%) patients used combination of pyrazinamide, capreomycin, levofloxacin, ethionamide and cycloserine (Pz-Cm-Lfx-Eto-Cs). All patients experienced side effects during therapy and the majority of them (91%) had gastroenteropathy and rheumatism. Tentamen suicide was detected in one patient. Conclusions: The MDR TB patients had history of tuberculosis therapy. The majority of patients used combination of Pz-Cm-Lfx-Eto-Cs. All patients experienced side effects during MDR TB therapy. [AMJ.2016;3(4):526–32]
Characteristics of Asthma Patients Seeking Care at West Java’s Top Referral Hospital, Indonesia Juan Achmad Yudistira; Emmy Hermiyanti Pranggono; Anna Tjandrawati; Primal Sudjana
Althea Medical Journal Vol 4, No 1 (2017)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (541.508 KB)

Abstract

Background: The increasing incidence of asthma in many countries in recent decades makes asthma a global health problem. The aim of the study was to determine the characteristics of asthma patients at the Respirology Outpatient Clinic of Dr. Hasan Sadikin General Hospital as West Java’s Top referral hospital. Methods: The study used a cross-sectional design. The study population was the medical record data of asthma patients at the Respirology Outpatient Clinic during June 2012–June 2013. There were 1,591 patient’s medical records at the Respirology Outpatient Clinic of Dr. Hasan Sadikin General Hospital Bandung in that period and 140 medical records were diagnosed with asthma. Seventy medical records were excluded because of inadequate data and 70 medical records were the sample of this study. The collected data were presented using percentage. Results: Seventy percent of the cases were female. From these cases 34% of patients   were aged 51–60 years. The partially controlled type was the most frequent type of asthma (62%). The most common sign and symptom was shortness of breath (86%). The most common drug used was Beta 2 agonist drugs (90%).Conclusions: The characteristic of asthma is that the patients are mostly female. Mostly the patients were in the age range of 51–60 years. The partially controlled type is the most frequent type of asthma. Shortness of breath is the most common clinical manifestation in asthma. Beta 2 agonist is the most used drug for asthma. [AMJ.2017;4(1):78–82]DOI: 10.15850/amj.v4n1.1025
Hook effect and serum KL-6 in Patients with Systemic Sclerosis-Associated Interstitial Lung Disease (SSc-ILD) Emmy Hermiyanti Pranggono; Valentine Natasya Moenardi; Alvy Syukrie; Sumartini Dewi
International Journal of Integrated Health Sciences Vol 9, No 2 (2021)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v9n2.2488

Abstract

Objective To determine whether serum KL-6 can be used as an alternative diagnostic tool for Systemic Sclerosis-associated ILD (SSc-ILD).Method This was a cross-sectional study with compatibility analysis of SSc patients visiting the rheumatology clinic of Dr. Hasan Sadikin General Hospital, Bandung, Indonesia in 2019-2020. Inclusion criteria were aged 18-60 years, diagnosed with SSc, restrictive spirometry results followed by HRCT thorax, having stored biological materials (<2 years) for serum KL-6 examination, and body mass index of <23 kg/m2. Patients with pneumonia, tuberculosis, history of tuberculosis, malignancy, and cardiac decompensation were excluded. Serum KL-6 level of >397.5 unit/mL was declared as ILD. The compatibility analysis was performed using the Cohen’s Kappa test.Results: Thirty-eight subjects, mostly women (94.7%), with mean age of 39 years participated in this study. Most of the subjects suffered from diffuse systemic sclerosis subtypes (57.9%). Subjects had received cyclophosphamide (10.5%), MMF (2.6%), and other medications. Almost all subjects (97.4%) demonstrated ILD features on HRCT thorax. The median serum KL-6 level was 53.22 Units/mL, which was much lower than the findings in other studies, but the hook effect could not be proven. The Kappa coefficient was found to be 0.003 with a p-value of 0.811.Conclusion There is no compatibility between serum KL-6 level and ILD features based on HRCT thorax in SSc-ILD. The presence of hook effect needs more attention.
The Combination of NLCR and Enhances the Sepsis-3 Strategy Emmy Hermiyanti Pranggono; Endah Nurul Aini; Uun Sumardi; Yovita Hartranti; Adhi Kristianto Sugianli
Folia Medica Indonesiana Vol. 58 No. 2 (2022): June
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (751.686 KB) | DOI: 10.20473/fmi.v58i2.31051

Abstract

Highlights: The combination of NLCR and PLR will improve the ability to distinguish infection rather than noninfection in the emergency setting for early antibiotic prescribing as well as the sepsis-3 strategy. The diagnostic value of PLR in adult bacterial sepsis patients has never been studied.   Abstract: According to Sepsis-3, antibiotics should be administered in the first hour of diagnosis of sepsis. Still, there is difficulty in differentiating between bacterial and nonbacterial infections and a lack of a rapid diagnostic tool to distinguish them. This study evaluated the diagnostic value of NLCR and PLR in suspected bacterial sepsis. The diagnostic value of PLR in adult bacterial sepsis patients has never been studied. This study was a retrospective study from the medical record of Dr. Hasan Sadikin Hospital Bandung. All patients at age ≥ 18 years diagnosed with sepsis based on ICD-10 code and qSOFA ≥ 2 were included. We calculated sensitivity, specificity, NPV, PPV, positive LR, and AUC of NLCR and PLR. There were 177 patients included in this study. The sensitivity of NLCR was 69.5%, specificity was 34.7%, NPV was 56.9%, PPV was 47.9%, and LR+ was 1.06, while the sensitivity of PLR was 62.2%, specificity was 38.9%, NPV was 54.4%, PPV was 46.8%, and LR+ was 1.02. We obtained cut-off values for NLCR 11.06, AUC 0.500, PLR 222.41, and AUC 0.497. The low value of AUC NLCR and PLR was due to prior antibiotic use. The combination of NLCR and PLR had higher positive LR (1.16) and specificity (54.7%), and also, according to NLCR, we had the highest sensitivity (69.5%). The combination of NLCR and PLR enhances the sepsis-3 strategy because it can be used as screening tools for bacterial sepsis, and antibiotics can also be administered in the first hour of managing sepsis, particularly in the emergency ward.
Primary Biliary Cirrhosis Irvan Nugraha; Guntur Darmawan; Emmy Hermiyanti Pranggono; Yudi Wahyudi; Nenny Agustanti; Dolvy Girawan; Begawan Bestari
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 19, No 3 (2018): VOLUME 19, NUMBER 3, December 2018
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (308.295 KB) | DOI: 10.24871/1932018195-200

Abstract

Primary biliary cirrhosis (PBC) is an inflammatory disease or chronic liver inflammation, with slow progressive characteristic and is an unknown cholestatic liver disease and commonly happen in middle-aged women. The incidence of PBC is 0.03 – 5.8 per 100,000 people per year, prevalence of 1.91-40.2 per 100,000 people and continues to increase. Based on the American Association for Study of Liver Disease criteria, the diagnosis of PBC is made in the presence of two out of three criteria, which are increase of alkaline phosphatase, positive antimitochondrial antibodies (AMA), and histopathology examination.We reported a case which is very rarely found; a 47-year-old women with the chief complaints of decrease consciousness and jaundice. In physical examination, there were anaemic conjunctiva, icteric sclera, hepatosplenomegaly, palmar erythema, and liver nails. In the patient, there was no evidence of obstruction in imaging with two-fold increase of alkaline phosphatase and positive AMA test. Patient was hospitalised to slow down the progression of the disease and to overcome the signs (e.g. pruritus, osteoporosis and sicca syndrome).
Co-Authors Adhi Kristianto Sugianli Alvy Syukrie Anna Tjandrawati Begawan Bestari Dewi, Sumartini Dolvy Girawan Endah Nurul Aini Guntur Darmawan Guntur Darmawan Irvan Nugraha Juan Achmad Yudistira Muhammad Begawan Bestari Nenny Agustanti Nugraha, Irvan Primal Sudjana Rahmawati, Rika Nurlaily Rika Nurlaily Rahmawati Rovina Ruslami, Rovina Uun Sumardi, Uun Valentine Natasya Moenardi Yovita Hartranti Yudi Wahyudi Yudi Wahyudi Yudistira, Juan Achmad