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All Journal The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
Rudi Wisaksana
Division of Infectious and Tropical Disease, Department of Internal Medicine, Faculty of Medicine, Universitas Padjadjaran/Hasan Sadikin General Hospital, Bandung
Medicine & Pharmacology

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Gut Microbiota in Human Immunodeficiency Virus Infection Rudi Wisaksana; Guntur Darmawan; Nenny Agustanti; Dolvy Girawan
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 20, No 1 (2019): VOLUME 20, NUMBER 1, April 2019
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (534.325 KB) | DOI: 10.24871/201201938-43

Abstract

Human microbiota, majority presents in human gastrointestinal tract, plays crucial role in body physiological functions, such as immune system. Human immunodeficiency virus (HIV) infection impairs gut barrier and alter the microbiota ecosystem, called dysbiosis. Different phase of HIV infection demonstrates different composition of gut microbiota. Antiretroviral treatment might improve the CD4 level, however, it inconsistently restore the gut ecosystem. Some studies in prebiotic and probiotic revealed the potential effect in reducing inflammation and restoring gut microbiota.
Co-Authors Dolvy Girawan Guntur Darmawan Nenny Agustanti