Article Per Year (5 Year)
p-Index From 2020 - 2025
0.947
P-Index
This Author published in this journals
All Journal International Journal of Public Health Science (IJPHS) Medical and Health Science Journal Hubungan Tingkat Pengetahuan Petugas Pengelola Obat dengan Tingkat Ketersediaan Obat Di Puskesmas Kota Malang Jurnal Sains dan Kesehatan
I Gusti Agung Ari Kusuma Yana
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Social Sciences

Published : 4 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 4 Documents
Search

 1 
A Systematic Review: Comparison of triple drug therapy versus double drug therapy for Lymphatic Filariasis I Gusti Agung Ari Kusuma Yana
Jurnal Ilmu Kesehatan dan Kesehatan Vol 5 No 1 (2021): FEBRUARY
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v5i1.1878

Abstract

Background: Lymphatic filariasis is a parasitic infection caused by nematodes such as filaria Wuchereria bancrofti, Brugia malayi, and Brugia timori. These parasites can be transmitted through mosquito bites such as several species of mosquitoes, particularly Anopheles, Aedes, Culex, and Mansonia with geographical variations in the dominant vector identity. The main strategy used consists of community-wide mass drug administration (MDA) for the entire population at risk to stop disease transmission and prevent infectious morbidity. WHO recommends the use of annual medication in combination with the triple drug ivermectin therapy. Objective: To compare DEC and albendazole (IDA) versus the two drugs albendazole and diethycarbamazine or albendazole and ivermectin therapy. Methods: The literature search was carried out independently by the researcher using the Sciencedirect, Pubmed, and Cochrane online databases without limiting the type of study or the year of publication. The keywords used in this study were combined with the Boolean operator, namely "AND" namely ((((Lymphatic filariasis) AND (albendazole)) AND (diethylcarbamazine)) AND (ivermectin)) AND (compare). Results: Where triple drug therapy was significantly better in reducing and clearing microfilariae and worm nests in patients with lymphatic filariasis compared to two drug therapy alone. However, side effects occur more frequently in the combination of three therapies. The average side effects were low, such as headaches, joint pain, fatigue, and nausea. Conclusion: although it has relatively low side effects that occur in three drug combinations rather than two drug combination therapy, triple therapy combination therapy is more effective than two drug therapy in treating lymphatic filariasis disease.
Efektivitas Dan Keamanan Terapi dengan Rejimen Bedaquiline dalam Terapi Multidrug-Resistant Tuberculosis (TB-MDR): Kajian Sistematis Yana, I Gusti Agung Ari Kusuma
Pharmaceutical Journal of Indonesia Vol. 7 No. 2 (2022)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.pji.2022.007.02.8

Abstract

MDR-TB is a tuberculosis disease caused by Mycobacterium tuberculosis which is resistant to isoniazid and rifampin with or without resistance to other first-line drugs. The development of drug-resistant tuberculosis is causing worldwide concern. Globally in 2019, almost half a million TB sufferers of which 78% had MDR-TB. In recent years, MDR-TB patients increased by 10% from 186,883 patients in 2018 to 206,030 in 2019. Bedaquiline has been recommended by WHO guidelines. Studies related to the effectiveness and safety of Bedaquiline are still few so that there is a need for qualified information to prepare a country, especially Indonesia, for the use of Bedaquiline therapy, especially since Indonesia is ranked second out of two-thirds of the total global TB. Objective: to describe the effectiveness and safety of Bedaquiline in combination therapy for the treatment of MDR-TB. Methods: The literature search was carried out independently by researchers using the online databases of Science Direct, Pubmed, and Cochrane without restrictions on the type of research and year of publication. The keywords used in this study were combined with Boolean operators, namely “bedaquiline” AND “tuberculosis” AND “multi-drug resistant”. Results: Seven studies met the inclusion criteria, the intervention of giving Bedaquiline for 24 weeks can reduce the average time of culture conversion by about 60-85 days. The percentage of culture conversion rate was higher with Bedaquiline (range 70-85%) than placebo (58%). The most common side effects are nausea and hyperuricemia. The majority of studies report a prolongation of the QT interval in patients treated with Bedaquiline. Conclusion: This systematic review showed that Bedaquiline is effective and safe to use in the treatment of MDR-TB. However, serious side effects of QT prolongation occurred in some respondents treated with Bedaquiline. Further studies need to be conducted to monitor the side effects of QT prolongation associated with the administration of Bedaquiline in the treatment of MDR-TB.
Self-medication practices among customers at non-pharmacy outlets during COVID-19 pandemic in Indonesia Wibowo, Yosi Irawati; Kusuma Yana, I Gusti Agung Ari; Puspa Sari, Gusti Ayu Putu Laksmi; Sunderland, Bruce; Setiadi, Adji Prayitno
International Journal of Public Health Science (IJPHS) Vol 13, No 4: December 2024
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v13i4.24136

Abstract

A cross-sectional study was performed to describe self-medication practices of customers at kiosks and minimarkets in District X, Indonesia, during COVID-19 pandemic in 2021. A sample of 98 customers from 67 kiosks, and 100 customers from 52 minimarkets were interviewed using a validated questionnaire. Descriptive statistics were used to summarise the findings. Most drugs purchased at kiosks and minimarkets were general sales drugs, i.e., analgesic-antipyretic (64.3% versus 46.0%); however, prescription drug sales were reported (3.1% vs 3.0%, respectively). Kiosk and minimarket customers purchased medications mainly based on the recommendations of non-health workers (69.4% vs. 34.0%, respectively), or electronic media (36.7% vs. 43.0%, respectively). The reasons to choose kiosks or minimarkets included accessibility, personal preferences, and service quality. Most kiosk/minimarket customers had knowledge on the drug brand names and indications, but only some knew the composition (8.16% vs. 29.0%, respectively) or side effects (9.18% vs. 35.0%, respectively). These findings indicated limited quality assurance on self-medication practices at non-pharmacy outlets.
Cystic Fibrosis: Review I Gusti Agung Ari Kusuma Yana
Jurnal Sains dan Kesehatan Vol. 3 No. 1 (2021): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v3i1.231

Abstract

Cystic fibrosis (CF) is a reversed autosomal genetic disease that originates from some white or caucasian races. This condition is caused by mutations in the CFTR gene, especially the CFTR Phe508del. If CFTR damage or error occurs then normal function will be disrupted and have a clinical impact on other organs or multiorgan. Complications such as the pancreas, liver, digestive tract, bone, genital, and respiratory tract that can cause most deaths in patients with cystic fibrosis. Malabsorption, inflammation, infection and lung obstruction are signs of cystic fibrosis. Therapy for cystic fibrosis is limited to the improvement of the airway mokus, recovery of infections maintained with antibiotics, improve physical health and nutrition of patients
Co-Authors Gusti Ayu Putu Laksmi Puspa Sari Setiadi, Adji Prayitno Sunderland, Bruce Wibowo, Yosi Irawati